Page last updated: 2024-08-23

staurosporine and Neurodegenerative Diseases

staurosporine has been researched along with Neurodegenerative Diseases in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, KH; Dhorma, LP; Hah, JM; Kim, MH; Kim, SY; Kumar, DN; Park, HG; Venkanna, A1
Blunt, M; Craggs, P; Hardwick, P; Hobbs, CI; Rowland, P; Shillings, A; Singh, O; Skarzynski, T; Smith, KJ; Tanner, R; Wall, I; Witty, DR1
Bandyopadhyay, U; Cuervo, AM; Figliola, M; Gauthier, S; Grubb, A; Kumar, AR; Levy, E; Mohan, P; Nixon, RA; Pawlik, M; Sahoo, S; Tizon, B; Uchiyama, Y; Yu, H1
Heinrich, M; Kaltschmidt, B; Kaltschmidt, C1
Cheng, T; Fernández, JA; Gelbard, H; Griffin, JH; Guo, H; Insalaco, R; Liu, D; Zlokovic, BV1
Alonso, M; Cortes-Canteli, M; Luna-Medina, R; Martínez, A; Perez-Castillo, A; Santos, A1
Boustany, RM; Guo, WX; Nikbakht, K; Puranam, KL; Qian, WH1
Cheetham, M; Fridlanskaya, I; Guzhova, I; Kislyakova, K; Margulis, B; Moskaliova, O; Tytell, M1
Ahlemeyer, B; Klumpp, S; Krieglstein, J1
Fiander, H; O'Reilly, N; Small, DL; Tauskela, J; Xia, Z1

Other Studies

10 other study(ies) available for staurosporine and Neurodegenerative Diseases

ArticleYear
Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Drug Discovery; Inflammation; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Nitric Oxide; Protein Kinase Inhibitors; Quinones; Spiro Compounds; Structure-Activity Relationship

2019
Crystal structures of ASK1-inhibtor complexes provide a platform for structure-based drug design.
    Protein science : a publication of the Protein Society, 2013, Volume: 22, Issue:8

    Topics: Binding Sites; Cardiovascular Diseases; Crystallography, X-Ray; Drug Design; Humans; Ligands; MAP Kinase Kinase Kinase 5; Neoplasms; Neurodegenerative Diseases; Sf9 Cells; Signal Transduction; Staurosporine

2013
Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.
    PloS one, 2010, Mar-23, Volume: 5, Issue:3

    Topics: Adenine; Animals; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line; Colchicine; Cystatin C; Enzyme Inhibitors; Lysosomes; Mice; Neurodegenerative Diseases; Neurons; Oxidative Stress; Rats; Rats, Sprague-Dawley; Staurosporine; TOR Serine-Threonine Kinases; Tubulin Modulators

2010
Stimulus-dependent activation of NF-kappaB specifies apoptosis or neuroprotection in cerebellar granule cells.
    Neuromolecular medicine, 2002, Volume: 2, Issue:3

    Topics: Amyloid beta-Peptides; Animals; Anthracenes; Apoptosis; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hydroxyl Radical; Iron; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; NF-kappa B; Oxidative Stress; Perylene; Protein Kinase C; Rats; Rats, Wistar; Staurosporine

2002
Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3.
    Neuron, 2004, Feb-19, Volume: 41, Issue:4

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Caspases; Cells, Cultured; Cerebral Cortex; Fetus; Flavoproteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neurodegenerative Diseases; Neurons; Protein C; Receptor, PAR-1; Receptors, Thrombin; Staurosporine; Tumor Suppressor Protein p53

2004
Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Alitretinoin; Anilides; Animals; Anti-Inflammatory Agents; Apoptosis; Astrocytes; Brain; Cell Death; Cell Line; Cell-Free System; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; In Vitro Techniques; Inflammation; Interleukin-6; Lipopolysaccharides; Lithium Chloride; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neurodegenerative Diseases; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Rats; Staurosporine; Thiazolidinediones; Time Factors; Transfection; Tretinoin; Tumor Necrosis Factor-alpha

2005
CLN3 defines a novel antiapoptotic pathway operative in neurodegeneration and mediated by ceramide.
    Molecular genetics and metabolism, 1999, Volume: 66, Issue:4

    Topics: Apoptosis; Blotting, Western; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Ceramides; Cyclins; Dose-Response Relationship, Drug; Etoposide; Humans; Membrane Glycoproteins; Models, Biological; Molecular Chaperones; Neurodegenerative Diseases; Poly(ADP-ribose) Polymerases; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae Proteins; Sphingosine; Staurosporine; Time Factors; Transfection; Vincristine

1999
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance.
    Brain research, 2001, Sep-28, Volume: 914, Issue:1-2

    Topics: Adenosine Triphosphate; Apoptosis; Carcinogens; Cell Differentiation; Cell Survival; Central Nervous System; Enzyme Inhibitors; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Immunohistochemistry; Models, Biological; Neurodegenerative Diseases; Neurofilament Proteins; Neuroglia; Neurons; Phorbol Esters; Staurosporine; Stress, Physiological; Tumor Cells, Cultured

2001
Release of cytochrome c into the extracellular space contributes to neuronal apoptosis induced by staurosporine.
    Brain research, 2002, May-03, Volume: 934, Issue:2

    Topics: Animals; Animals, Newborn; Antibodies; Apoptosis; Cell Differentiation; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Central Nervous System; Chick Embryo; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Space; Hippocampus; L-Lactate Dehydrogenase; Mitochondria; Neurodegenerative Diseases; Neurons; Rats; Rats, Inbred F344; Staurosporine

2002
Disparity between ionic mediators of volume regulation and apoptosis in N1E 115 mouse neuroblastoma cells.
    Brain research, 2002, Jul-12, Volume: 943, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Apoptosis; Bumetanide; Cell Membrane; Cell Size; Central Nervous System; Chloride Channels; Enzyme Inhibitors; Furosemide; Ion Channels; Mice; Neuroblastoma; Neurodegenerative Diseases; Neurons; Niflumic Acid; Potassium Channel Blockers; Potassium Channels; Potassium Chloride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Staurosporine; Tumor Cells, Cultured

2002