staurosporine has been researched along with Nerve Degeneration in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 16 (64.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerget, M; Landwehrmeyer, GB; Lewerenz, J; Linkus, B; von Einem, B; Voss, TD | 1 |
| Choi, SY; Kanakura, Y; Kim, H; Kim, WK; Oh, YJ; Park, KA; Shibayama, H; Shin, DI; Yun, N | 1 |
| Daudt, DR; Yorio, T | 1 |
| Dave, JR; Ling, G; Lu, XM; Tortella, FC; Williams, AJ | 1 |
| Lovell, MA; Markesbery, WR; Xie, C; Xiong, S | 1 |
| Halaris, A; Piletz, JE; Regunathan, S; Zhu, MY | 1 |
| Cardozo-Pelaez, F; Chan, SL; Chrest, FJ; Emokpae, R; Gorospe, M; Kruman, II; Mattson, MP; Smilenov, L; Wersto, RP | 1 |
| Bantubungi, K; Blum, D; Brotchi, J; Brouillet, E; Chtarto, A; Déglon, N; Galas, MC; Greco, A; Jacquard, C; Levivier, M; Minghetti, L; Pintor, A; Popoli, P; Schiffmann, SN; Tai, K; Tenenbaum, L | 1 |
| Bertram, L; Bissada, N; Deng, Y; Doty, CN; Graham, RK; Haigh, B; Hayden, MR; Leavitt, BR; Lu, G; Murphy, Z; Nicholson, DW; Pearson, J; Raymond, LA; Roy, S; Shehadeh, J; Slow, EJ; Warby, SC; Wellington, CL | 1 |
| Choi, BH; Choi, JK; Ha, Y; Huang, X; Park, H; Park, HC; Park, JO; Park, SR; Yoon, SH | 1 |
| Bronich, TK; Caplan, S; Gendelman, HE; Johnson, TV; Kipnis, J; Lin, J; Liu, J; Persidsky, Y; Ramirez, SH | 1 |
| Basta-Kaim, A; Budziszewska, B; Jagla, G; Jantas, D; Jaworska-Feil, L; Kubera, M; Lason, W; Leskiewicz, M; Nowak, W; Regulska, M | 1 |
| Gottardi-Littell, NR; Perez, RG; Sodhi, CP | 1 |
| Canzoniero, LM; Choi, DW; Csernansky, C; Demaro, J; Gwag, BJ; Koh, JY; Sensi, SL; Wie, MB | 1 |
| Henrich-Noack, P; Krieglstein, J; Prehn, JH | 1 |
| Haug, FM; Laake, JH; Ottersen, OP; Rundén, E; Seglen, PO; Shamloo, M; Wieloch, T | 1 |
| Duan, W; Mattson, MP; Rangnekar, VM | 1 |
| Comas, T; Fournier, M; Monette, R; Morley, P; Small, DL | 1 |
| Hill, IE; MacManus, JP; Murray, C; Rasquinha, I; Richard, J | 1 |
| Ahlemeyer, B; Becker, A; Krieglstein, J; Ravati, A | 1 |
| Ahlemeyer, B; Hühne, R; Junker, V; Krieglstein, J | 1 |
| Akaike, A; Honda, K; Kihara, T; Nakamizo, T; Sawada, H; Shibasaki, H; Shimohama, S | 1 |
| Cho, S; Dawson, G; Dawson, PE | 1 |
| Ensor, EA; Kinloch, RA; Latchman, DS; Smith, MD | 1 |
| Campenot, RB; Draker, DD; Walji, AH | 1 |
25 other study(ies) available for staurosporine and Nerve Degeneration
| Article | Year |
|---|---|
Ubiquitination and the proteasome rather than caspase-3-mediated C-terminal cleavage are involved in the EAAT2 degradation by staurosporine-induced cellular stress.
Topics: Animals; Caspase 3; Cells, Cultured; Enzyme Inhibitors; Excitatory Amino Acid Transporter 2; Humans; Mice; Nerve Degeneration; Proteasome Endopeptidase Complex; Staurosporine; Stress, Physiological; Ubiquitination | 2021 |
Nuclear translocation of anamorsin during drug-induced dopaminergic neurodegeneration in culture and in rat brain.
Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; Cell Fractionation; Cells, Cultured; Dopamine; Immunohistochemistry; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Male; Mesencephalon; Nerve Degeneration; Neurons; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staurosporine | 2011 |
FKBP51 protects 661w cell culture from staurosporine-induced apoptosis.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Gene Expression; Mice; Nerve Degeneration; Neurons; Neuroprotective Agents; NF-kappa B; Plasmids; Retina; Staurosporine; Tacrolimus; Tacrolimus Binding Proteins; Transfection | 2011 |
Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Conotoxins; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Nerve Degeneration; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staurosporine | 2002 |
Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibody Specificity; Antisense Elements (Genetics); Apoptosis; Blotting, Western; Cell Survival; Codon, Nonsense; Female; Genes, Wilms Tumor; Hippocampus; Humans; Immunohistochemistry; Male; Nerve Degeneration; Neurofibrillary Tangles; Neurons; Rats; Staurosporine | 2003 |
Effect of agmatine against cell death induced by NMDA and glutamate in neurons and PC12 cells.
Topics: Agmatine; Animals; Calcimycin; Cell Death; Cerebral Cortex; Enzyme Inhibitors; Fetus; Glutamic Acid; Ionophores; L-Lactate Dehydrogenase; N-Methylaspartate; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; PC12 Cells; Protein Kinase Inhibitors; Protein Kinases; Rats; Staurosporine | 2003 |
Cell cycle activation linked to neuronal cell death initiated by DNA damage.
Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Cells, Cultured; Colchicine; DNA Damage; DNA-Binding Proteins; Etoposide; Female; Homocysteine; Male; Methotrexate; Mice; Nerve Degeneration; Neurons; Protein Serine-Threonine Kinases; Rats; Staurosporine; Tumor Suppressor Proteins | 2004 |
Minocycline in phenotypic models of Huntington's disease.
Topics: Animals; Calpain; Caspases; Cell Death; Cells, Cultured; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalitis; Glutamic Acid; Huntingtin Protein; Huntington Disease; Male; Minocycline; Nerve Degeneration; Nerve Tissue Proteins; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Phenotype; Propionates; Quinolinic Acid; Rats; Rats, Inbred Lew; Rats, Wistar; Staurosporine | 2005 |
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.
Topics: Active Transport, Cell Nucleus; Animals; Brain; Caspase 6; Caspases; Cell Nucleus; Humans; Huntingtin Protein; Huntington Disease; Hydrolysis; Mice; Mice, Transgenic; Mutation; N-Methylaspartate; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Quinolinic Acid; Staurosporine | 2006 |
GM-CSF inhibits apoptosis of neural cells via regulating the expression of apoptosis-related proteins.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Brain Mapping; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Granulocyte-Macrophage Colony-Stimulating Factor; Male; Mice; Nerve Degeneration; Neurons; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; Staurosporine; Tumor Suppressor Protein p53; Up-Regulation | 2007 |
T cell independent mechanism for copolymer-1-induced neuroprotection.
Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cell Movement; Dendritic Cells; Enzyme Inhibitors; Female; Fluorescent Antibody Technique; Glatiramer Acetate; Humans; In Situ Nick-End Labeling; Nerve Crush; Nerve Degeneration; Neurons; Neuroprotective Agents; Optic Nerve; Peptides; Protein Kinase C-alpha; Rats; Rats, Inbred Lew; Rats, Nude; Staurosporine; T-Lymphocytes | 2007 |
Effects of neurosteroids on hydrogen peroxide- and staurosporine-induced damage of human neuroblastoma SH-SY5Y cells.
Topics: Apoptosis; Brain; Cell Line, Tumor; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Enzyme Inhibitors; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neuroblastoma; Neurons; Oxidants; Oxidative Stress; Phosphatidylinositol 3-Kinases; Pregnanolone; Pregnenolone; Staurosporine; Steroids | 2008 |
Phosphorylation of beta-amyloid precursor protein (APP) cytoplasmic tail facilitates amyloidogenic processing during apoptosis.
Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acids; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Apoptosis; Binding Sites; Brain; Down-Regulation; Endocytosis; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 3; Nerve Degeneration; PC12 Cells; Peptide Fragments; Phosphorylation; Protein Structure, Tertiary; Rats; Staurosporine | 2008 |
Staurosporine-induced neuronal apoptosis.
Topics: Alkaloids; Animals; Apoptosis; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Kainic Acid; Mice; Mice, Inbred Strains; N-Methylaspartate; Nerve Degeneration; Neurons; Staurosporine; Time Factors | 1995 |
TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms.
Topics: Animals; Apoptosis; Cell Death; Dose-Response Relationship, Drug; Hippocampus; Injections; Injections, Intraventricular; Ischemic Attack, Transient; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Nitric Oxide; Oxidation-Reduction; Pyramidal Cells; Rats; Rats, Wistar; Staurosporine; Time Factors; Transforming Growth Factor beta | 1996 |
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Enzyme Inhibitors; Flavanones; Flavonoids; Genistein; Hippocampus; Indole Alkaloids; Male; Microscopy, Electron; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Degeneration; Neurons; Okadaic Acid; Organ Culture Techniques; Phosphoric Monoester Hydrolases; Propidium; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Staurosporine; Sulfonamides | 1998 |
Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Carrier Proteins; Caspases; Cell Survival; Cells, Cultured; Dendrites; Female; Gene Expression Regulation; Glutamic Acid; Hippocampus; Intracellular Signaling Peptides and Proteins; Kainic Acid; Male; Mitochondria; Nerve Degeneration; Neurites; Neurons; Oligodeoxyribonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Synapses; Synaptosomes | 1999 |
Loss of cyclin D1 in necrotic and apoptotic models of cortical neuronal degeneration.
Topics: Animals; Apoptosis; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Fetus; G1 Phase; Glutamic Acid; Kinetics; Models, Neurological; Necrosis; Nerve Degeneration; Neurons; Rats; Resting Phase, Cell Cycle; S Phase; Staurosporine | 1999 |
Despite the internucleosomal cleavage of DNA, reactive oxygen species do not produce other markers of apoptosis in cultured neurons.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Caspases; Cell Nucleus; Cholinesterase Inhibitors; Comet Assay; Cycloheximide; DNA Fragmentation; Enzyme Inhibitors; Female; Free Radical Scavengers; Glutamic Acid; Metalloporphyrins; Molsidomine; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nucleosomes; Oxidation-Reduction; Phenanthrolines; Pregnancy; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Staurosporine; Uric Acid | 2000 |
Preconditioning-induced neuroprotection is mediated by reactive oxygen species.
Topics: Animals; Cells, Cultured; Chick Embryo; Ferrous Compounds; Free Radical Scavengers; Glutamic Acid; Ischemic Preconditioning; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Reactive Oxygen Species; Staurosporine; Xanthine; Xanthine Oxidase | 2000 |
Neuroprotective effects of NV-31, a bilobalide-derived compound: evidence for an antioxidative mechanism.
Topics: Animals; Antioxidants; Apoptosis; Astrocytes; Brain Injuries; Brain Ischemia; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Flavonoids; Ginkgo biloba; Mice; Nerve Degeneration; Neurons; Neuroprotective Agents; Phytotherapy; Plant Extracts; Plants, Medicinal; Pyrans; Rats; Rats, Inbred F344; Reactive Oxygen Species; Staurosporine; Telencephalon | 2001 |
Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons.
Topics: Alzheimer Disease; Animals; Apoptosis; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Fetus; Glutamic Acid; Menopause; Nerve Degeneration; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Staurosporine | 2001 |
Role of palmitoyl-protein thioesterase in cell death: implications for infantile neuronal ceroid lipofuscinosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Chromones; Daunorubicin; Enzyme Inhibitors; Etoposide; Humans; Infant; Morpholines; Nerve Degeneration; Neuroblastoma; Neuronal Ceroid-Lipofuscinoses; Neurons; Nucleic Acid Synthesis Inhibitors; Sphingosine; Staurosporine; Thiolester Hydrolases; Transfection; Tumor Cells, Cultured | 2001 |
The POU domain transcription factor Brn-3a protects cortical neurons from apoptosis.
Topics: Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Survival; Cerebral Cortex; DNA-Binding Proteins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Genetic Therapy; Genetic Vectors; Glutamic Acid; Green Fluorescent Proteins; Immunohistochemistry; Indicators and Reagents; Luminescent Proteins; Nerve Degeneration; Neurons; Neurotoxins; Protein Structure, Tertiary; Rats; Rats, Sprague-Dawley; Simplexvirus; Staurosporine; Transcription Factor Brn-3; Transcription Factors | 2001 |
Effects of sphingosine, staurosporine, and phorbol ester on neurites of rat sympathetic neurons growing in compartmented cultures.
Topics: Alkaloids; Animals; Axons; Cells, Cultured; Immunoglobulin G; Microscopy, Phase-Contrast; Nerve Degeneration; Nerve Growth Factors; Neurons; Protein Kinase C; Rats; Sphingosine; Staurosporine; Sympathetic Nervous System; Tetradecanoylphorbol Acetate | 1991 |