staurosporine has been researched along with Necrosis in 72 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (12.50) | 18.2507 |
| 2000's | 49 (68.06) | 29.6817 |
| 2010's | 13 (18.06) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Daver, NG; Glass, WF; Kala, J; Pankow, JD; Richard-Carpentier, G | 1 |
| Dye, JR; Piantadosi, CA; Pisetsky, DS; Spencer, DM | 1 |
| Baines, CP; Davis, JW; Edwards, MA; Krenz, M; Marshall, KD | 1 |
| Casanelles, E; Garcia-Belinchón, M; Granados-Colomina, C; Iglesias-Guimarais, V; Martínez-Escardó, L; Pascual-Guiral, S; Ribas, J; Sánchez-Osuna, M; Yuste, VJ | 1 |
| Donath, P; Engelmann, K; Knels, L; Valtink, M | 1 |
| Cortes-Hernandez, DG; Gamette, MJ; Jensen, JB; Porter, H | 1 |
| Auger, R; Daniel, H; Delarasse, C; Galante, M; Gonnord, P; Kanellopoulos, JM; Motta, I | 1 |
| Adams, SP; Barber, L; Connors, D; Hanumegowda, UM; Jayachandra, S; Wu, Y | 1 |
| Jantas, D; Jaworska-Feil, L; Lason, W; Lipkowski, AW | 1 |
| Hayes, RL; Larner, SF; Liu, MC; Wang, KK; Zhang, Z; Zheng, W | 1 |
| Hisakura, K; Ikeda, N; Ikeda, O; Kawasaki, T; Kohno, K; Matsuo, R; Murata, S; Myronovych, A; Nakano, Y; Ohkohchi, N; Pak, S; Takahashi, K; Watanabe, M | 1 |
| Dupont-Versteegden, EE; Ferry, AL; Vanderklish, PW | 1 |
| Almeida, S; de Brito, OM; Ferreira, IL; Lombardi, V; Louros, S; Oliveira, CR; Rego, AC; Ribeiro, M; Rosenstock, TR | 1 |
| Lipnik-Štangelj, M; Šimenc, J | 1 |
| Barna, G; Bauer, PI; Dunai, ZA; Imre, G; Korcsmaros, T; Mihalik, R; Petak, I | 1 |
| Hoffmeyer, P; Kindler, V; Laumonier, T; Menetrey, J; Pradier, A | 1 |
| Motadi, LR; Sayed, Y; Thafeni, MA | 1 |
| Chain, WJ; Fash, DM; Li, Z; Nakashige, ML; Ramos, JW; Sulzmaier, FJ | 1 |
| Anagli, J; Cagmat, EB; Guingab-Cagmat, JD; Kobeissy, FH; Newsom, K; Vakulenko, A; Wang, KK; Zoltewicz, S | 1 |
| Filgueira, L; Forte, P; Groscurth, P; Matter-Reissmann, UB; Schneider, MK; Seebach, JD | 1 |
| McKeague, AL; Nelson, J; Wilson, DJ | 1 |
| Gada, H; Guttmann, RP; Neumar, RW; Siman, R; Xu, YA | 1 |
| Almaas, R; Lindstad, JK; Pleasure, D; Pytte, M; Rootwelt, T; Saugstad, OD; Wright, M | 1 |
| Hosoya, T; Kawamura, T; Kikuchi, T; Ohno, T; Tsuboi, N; Utsunomiya, Y; Yamada, H | 1 |
| Chang, I; Cho, N; Koh, JY; Lee, MS | 1 |
| Bermudez, LE; Danelishvili, L; Li, YJ; McGarvey, J | 1 |
| Hirt, UA; Leist, M | 1 |
| Capodici, J; Karikó, K; Lamphier, M; Ni, H; Weissman, D | 1 |
| Bianchi, L; Bini, L; Citti, L; Evangelista, M; Liberatori, S; Mariani, L; Pallini, V; Poliseno, L; Rainaldi, G; Salvetti, A | 1 |
| Assefa, Z; Bultynck, G; Callewaert, G; De Smedt, H; Goris, J; Missiaen, L; Nadif Kasri, N; Parys, JB; Szlufcik, K; Vermassen, E | 1 |
| Imre, G; Kopper, L; Mihalik, R; Petak, I; Szende, B | 1 |
| Chen, GG; Leung, BC; Ng, HK; Poon, WS; Sin, FL | 1 |
| Bouleau, S; Costina-Parvu, I; Godefroy, N; Lemaire, C; Mignotte, B; Renaud, F; Rincheval, V; Trotot, P; Vayssière, JL | 1 |
| Jebe, E; Petrunkina, AM; Töpfer-Petersen, E | 1 |
| Choi, JJ; Pisetsky, DS; Reich, CF | 1 |
| Koike, T; Suzuki, M | 1 |
| Esposito, M; Gretzer, C; Suska, F; Tengvall, P; Thomsen, P | 1 |
| Chen, D; Gosslee, J; Langford, MP; Misra, RP; Redens, TB; Texada, DE | 1 |
| Chander, R; Deorukhkar, AA; Pandey, R; Sainis, KB | 1 |
| Dunai, Z; Imre, G; Mihalik, R; Petak, I | 1 |
| Numata, T; Okada, Y; Sato, K; Wehner, F | 1 |
| Beyaert, R; Declercq, W; Fiers, W; Vandenabeele, P; Vercammen, D | 1 |
| Beckman, M; Hallberg, E; Imreh, G; Iverfeldt, K | 1 |
| Dewson, G; Levi-Schaffer, F; Moqbel, R; Walsh, GM; Wardlaw, AJ | 1 |
| Kruman, II; Mattson, MP | 1 |
| Edwards, AD; Greenwood, K; Joashi, UC; Kozma, M; Mazarakis, ND; Mehmet, H; Taylor, DL | 1 |
| Bennett, MR; Champagne, MJ; Dumas, P; Hamet, P; Orlov, SN; Tremblay, J | 1 |
| Gwag, BJ; Jou, I; Ko, HW; Noh, JS; Ryu, BR | 1 |
| Dietz, R; Haller, H; Li, PF; Maasch, C; von Harsdorf, R | 1 |
| Comas, T; Fournier, M; Monette, R; Morley, P; Small, DL | 1 |
| Denner, L; Haidacher, SJ; Li, X; Mannucci, R; Marani, M; Marcelli, M; Nicoletti, I; Sturgis, L; Trial, JA | 1 |
| Beart, PM; Bernard, O; Cheung, NS; John, CA; Pascoe, CJ | 1 |
| Andrews, D; Daugas, E; Ferri, KF; Irinopoulou, T; Kroemer, G; Larochette, N; Leber, B; Penninger, J; Prévost, MC; Susin, SA; Zamzami, N | 1 |
| Allen, JW; Faden, AI; Knoblach, SM | 1 |
| Gantner, F; Hirt, UA; Leist, M | 1 |
| Bergk, A; Dirnagl, U; Freyer, D; Harms, C; Hörtnagl, H; Lautenschlager, M; Weber, JR; Weih, M | 1 |
| Kong, JY; Rabkin, SW | 1 |
| Leist, M; Nicotera, P; Single, B | 1 |
| Asrari, M; Lobner, D | 1 |
| Bergk, A; Dirnagl, U; Freyer, D; Harms, C; Herwig, U; Hörtnagl, H; Kapinya, K; Katchanov, J; Lautenschlager, M; Megow, D; Weber, JR | 1 |
| Hara, H; Kimura, G; Mak, TW; Miyazaki, K; Nomoto, K; Sasaki, M; Yoshida, H | 1 |
| Choi, WS; Chung, CW; Jin, BK; Jung, YK; Kim, SU; Lee, EH; Oh, TH; Oh, YJ; Saido, TC | 1 |
| Corbach, S; Prescott, AR; Savill, J; Spruce, BA; Wiegand, UK | 1 |
| Calabrese, EJ | 1 |
| Belka, C; Berdel, WE; Kreuter, M; Los, M; Renz, A; Schulze-Osthoff, K | 1 |
| Morisco, C; Sadoshima, J; Seta, K; Vatner, SF; Yamamoto, S | 1 |
| Casiano, CA; Johnson, N; Molinaro, C; Wu, X | 1 |
| Benjamins, JA; Studzinski, DM | 1 |
| Golob, N; Grygar, E; Windisch, M; Wronski, R | 1 |
| Feng, G; Kaplowitz, N | 1 |
| Ghelli, A; Porcelli, AM; Rugolo, M; Zanna, C | 1 |
| Casiano, CA; Chan, EK; Fritzler, MJ; Hamel, JC; Molinaro, C; Nozawa, K | 1 |
2 review(s) available for staurosporine and Necrosis
| Article | Year |
|---|---|
Intracameral toxicity of bacterial components muramyl dipeptide and staurosporine: ciliary cyst formation, epithelial cell apoptosis and necrosis.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Apoptosis; Bacteria; Caspase 3; Caspases; Ciliary Body; Cysts; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Necrosis; Placebos; Rabbits; Staurosporine; Uveitis | 2006 |
Apoptosis: biphasic dose responses.
Topics: Animals; Antioxidants; Apoptosis; Cycloheximide; Dementia; Dimethylformamide; Dose-Response Relationship, Drug; Enzyme Inhibitors; Homeostasis; Humans; Melatonin; Necrosis; Nootropic Agents; Protein Synthesis Inhibitors; Radiation Injuries; Staurosporine; Tacrine; Tumor Necrosis Factor-alpha | 2001 |
70 other study(ies) available for staurosporine and Necrosis
| Article | Year |
|---|---|
Unique case of ANCA-negative pauci-immune necrotizing glomerulonephritis with diffuse alveolar hemorrhage, potentially associated with midostaurin.
Topics: Acute Kidney Injury; Administration, Intravenous; Antibodies, Antineutrophil Cytoplasmic; Biopsy; Combined Modality Therapy; Cyclophosphamide; Glomerulonephritis; Glucocorticoids; Hemorrhage; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Lung Diseases; Methylprednisolone; Middle Aged; Necrosis; Plasma Exchange; Protein Kinase Inhibitors; Renal Dialysis; Staurosporine; Treatment Outcome | 2020 |
The release of microparticles and mitochondria from RAW 264.7 murine macrophage cells undergoing necroptotic cell death in vitro.
Topics: Animals; Apoptosis; Caspase Inhibitors; Cell Death; Cell-Derived Microparticles; Macrophages; Mice; Mitochondria; Necrosis; RAW 264.7 Cells; Staurosporine | 2018 |
Proteomic mapping of proteins released during necrosis and apoptosis from cultured neonatal cardiac myocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Biomarkers; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Proteins; Proteomics; Rats; Staurosporine; Time Factors | 2014 |
An Early and Robust Activation of Caspases Heads Cells for a Regulated Form of Necrotic-like Cell Death.
Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Carrier Proteins; Caspases; Cell Line, Tumor; Chromatin; Colchicine; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Microfilament Proteins; Necrosis; Neurons; Nocodazole; Peptidomimetics; Quinolines; Rotenone; Signal Transduction; Staurosporine; Thapsigargin | 2015 |
Effect of different culture media and deswelling agents on survival of human corneal endothelial and epithelial cells in vitro.
Topics: Apoptosis; Cell Line; Cell Survival; Culture Media; Culture Media, Serum-Free; Dextrans; Endothelium, Corneal; Enzyme Inhibitors; Epithelium, Corneal; Flow Cytometry; Humans; Hydrogen Peroxide; Hydroxyethyl Starch Derivatives; Microscopy, Phase-Contrast; Necrosis; Organ Culture Techniques; Oxidants; Plasma Substitutes; Reactive Oxygen Species; Staurosporine | 2016 |
Asexual blood stages of Plasmodium falciparum exhibit signs of secondary necrosis, but not classical apoptosis after exposure to febrile temperature (40 C).
Topics: Animals; Antimalarials; Apoptosis; Caspases; Chloroquine; DNA Fragmentation; DNA, Protozoan; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Glucose; Humans; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Necrosis; Plasmodium falciparum; Protozoan Proteins; Staurosporine; Temperature | 2008 |
Neural progenitor cell death is induced by extracellular ATP via ligation of P2X7 receptor.
Topics: Adenosine Triphosphate; Animals; Calcium; Caspases; Cell Death; Cell Differentiation; Cells, Cultured; Chelating Agents; Corpus Striatum; Egtazic Acid; Embryo, Mammalian; Embryonic Stem Cells; Enzyme Inhibitors; Extracellular Fluid; L-Lactate Dehydrogenase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neurons; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2009 |
Multiplexed assay panel of cytotoxicity in HK-2 cells for detection of renal proximal tubule injury potential of compounds.
Topics: Apoptosis; Cells, Cultured; Cost-Benefit Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Kidney Tubules, Proximal; Necrosis; Perhexiline; Staurosporine; Time Factors; Toxicity Tests | 2009 |
Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Female; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kainic Acid; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Pregnancy; Proto-Oncogene Proteins c-akt; Quisqualic Acid; Staurosporine; Thyrotropin-Releasing Hormone | 2009 |
Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways.
Topics: Amino Acid Sequence; Animals; Apoptosis; Calpain; Caspases; Cell Death; Edetic Acid; Marine Toxins; Necrosis; Oxocins; PC12 Cells; Rats; Spectrin; Staurosporine | 2009 |
Platelets prevent acute hepatitis induced by anti-fas antibody.
Topics: Acute Disease; Alanine Transaminase; Animals; Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Cell Line; Disease Models, Animal; Endothelial Cells; fas Receptor; Hepatitis; Hepatocytes; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Necrosis; Platelet Count; Polyethylene Glycols; Recombinant Proteins; Staurosporine; Thrombocytopenia; Thrombocytosis; Thrombopoiesis; Thrombopoietin; Time Factors | 2011 |
Enhanced survival of skeletal muscle myoblasts in response to overexpression of cold shock protein RBM3.
Topics: Animals; Apoptosis; Caspases; Cell Line; Cell Survival; Cold Shock Proteins and Peptides; Cold Temperature; Cytoprotection; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mice; Mitochondria; Myoblasts, Skeletal; Necrosis; RNA-Binding Proteins; Staurosporine; Time Factors; Transfection; Up-Regulation | 2011 |
FK506 ameliorates cell death features in Huntington's disease striatal cell models.
Topics: Animals; Apoptosis; Blotting, Western; Caspase 3; Cell Death; Cell Line; Corpus Striatum; Cytosol; DNA Fragmentation; Humans; Huntingtin Protein; Huntington Disease; Immunosuppressive Agents; Mice; Mice, Transgenic; Mitochondria; Necrosis; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Nitro Compounds; Nuclear Proteins; Propionates; Staurosporine; Subcellular Fractions; Tacrolimus | 2011 |
Staurosporine induces apoptosis and necroptosis in cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Apoptosis; Astrocytes; Caspases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Imidazoles; Indoles; Necrosis; Rats; Rats, Wistar; Receptor-Interacting Protein Serine-Threonine Kinases; Staurosporine | 2012 |
Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells.
Topics: Apoptosis; Caspase Inhibitors; Caspases; Flow Cytometry; Humans; Necrosis; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; U937 Cells | 2012 |
Low molecular weight dextran sulfate binds to human myoblasts and improves their survival after transplantation in mice.
Topics: Animals; Apoptosis; Cell Differentiation; Cell Proliferation; Child, Preschool; Dextran Sulfate; Female; Graft Survival; Humans; Infant; Killer Cells, Natural; Luminescent Measurements; Mice; Mice, Inbred NOD; Molecular Weight; Myoblasts; Necrosis; Staurosporine; Transplantation, Heterologous | 2013 |
Euphorbia mauritanica and Kedrostis hirtella extracts can induce anti-proliferative activities in lung cancer cells.
Topics: Apoptosis; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, Thin Layer; Chrysobalanaceae; Cyclin D1; DNA Fragmentation; DNA-Binding Proteins; Drug Screening Assays, Antitumor; Euphorbia; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Necrosis; Neoplasms, Squamous Cell; Plant Extracts; Staurosporine; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases | 2012 |
Englerin a selectively induces necrosis in human renal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Calcium; Cell Line, Tumor; Cell Survival; Chloroquine; Cytoplasm; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Kidney Neoplasms; Molecular Structure; Necrosis; Reactive Oxygen Species; Sesquiterpenes, Guaiane; Staurosporine | 2012 |
In vitro MS-based proteomic analysis and absolute quantification of neuronal-glial injury biomarkers in cell culture system.
Topics: Animals; Apoptosis; Biomarkers; Brain Injuries; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Glial Fibrillary Acidic Protein; Marine Toxins; Mass Spectrometry; N-Methylaspartate; Necrosis; Neuroglia; Neurons; Oxocins; Protein Interaction Maps; Proteomics; Rats; Rats, Sprague-Dawley; Signal Transduction; Staurosporine; Ubiquitin Thiolesterase | 2012 |
Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression.
Topics: Amino Acid Chloromethyl Ketones; Ammonium Chloride; Animals; Anti-Bacterial Agents; Antigens, Heterophile; Apoptosis; Calcium; Cells, Cultured; Coculture Techniques; Cysteine Endopeptidases; Cytotoxicity, Immunologic; Dactinomycin; Endothelium, Vascular; Enzyme Inhibitors; Exocytosis; Fas Ligand Protein; Genes, bcl-2; Graft Rejection; Granzymes; Humans; Killer Cells, Natural; Macrolides; Membrane Glycoproteins; Microscopy, Electron; Necrosis; Perforin; Pore Forming Cytotoxic Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Serine Endopeptidases; Staurosporine; Swine; Tumor Necrosis Factor-alpha; Ubiquitin | 2002 |
Staurosporine-induced apoptosis and hydrogen peroxide-induced necrosis in two human breast cell lines.
Topics: Apoptosis; Breast Neoplasms; Cell Line; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Necrosis; Staurosporine; Tumor Cells, Cultured | 2003 |
Cross-talk between calpain and caspase proteolytic systems during neuronal apoptosis.
Topics: Apoptosis; Blotting, Western; Calcium-Binding Proteins; Calpain; Caspase 3; Caspases; Cell Line; Cell Membrane; Cell Nucleus; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Microscopy, Fluorescence; Necrosis; Neurons; Staurosporine; Time Factors; Transfection; Tumor Cells, Cultured; Up-Regulation | 2003 |
Acidosis has opposite effects on neuronal survival during hypoxia and reoxygenation.
Topics: Acidosis; Apoptosis; Caspase Inhibitors; Cell Death; Cell Hypoxia; Cell Line; Cell Nucleus; Cell Survival; Culture Media; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Free Radicals; Glucose; Humans; Hydrogen-Ion Concentration; N-Methylaspartate; Necrosis; Neurons; Oxygen; Poly(ADP-ribose) Polymerases; Staurosporine | 2003 |
Shedding of growth-suppressive gangliosides from glomerular mesangial cells undergoing apoptosis.
Topics: Animals; Apoptosis; bcl-X Protein; Cell Division; Cells, Cultured; Culture Media, Conditioned; Enzyme Inhibitors; Gangliosides; Glomerular Mesangium; Growth Inhibitors; Hydrogen Peroxide; Male; Necrosis; Oxidants; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Staurosporine; Ultraviolet Rays | 2003 |
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes.
Topics: Adenosine Triphosphate; Animals; Antigens, Polyomavirus Transforming; Antioxidants; Cell Death; Cell Line, Tumor; Cell Transformation, Neoplastic; Diabetes Mellitus, Experimental; Etoposide; Insulinoma; Interferon-gamma; Islets of Langerhans; NAD; Necrosis; Pancreatic Neoplasms; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Necrosis Factor-alpha; Zinc | 2003 |
Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells.
Topics: Antibiotics, Antitubercular; Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cell Line; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Macrophages; Mycobacterium tuberculosis; Necrosis; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-bcl-2; Pulmonary Alveoli; Rifampin; Staurosporine | 2003 |
Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells.
Topics: Animals; Annexin A5; Antibodies, Monoclonal; Apoptosis; Calcium; CD36 Antigens; Cell Line; Cell Membrane; Cells, Cultured; Escherichia coli; Formaldehyde; Humans; Inflammation; Ionomycin; Jumonji Domain-Containing Histone Demethylases; Jurkat Cells; Lipopolysaccharide Receptors; Liposomes; Macrophages; Membrane Lipids; Mice; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Necrosis; Oligomycins; Oligopeptides; Phagocytosis; Phosphatidylserines; Polymers; Receptors, Cell Surface; Staurosporine; Tumor Necrosis Factor-alpha | 2003 |
mRNA is an endogenous ligand for Toll-like receptor 3.
Topics: Blotting, Northern; Cell Line; Dendritic Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genistein; Humans; Interleukin-1 Receptor-Associated Kinases; Interleukin-8; Ligands; Luciferases; Membrane Glycoproteins; Necrosis; NF-kappa B; Nucleic Acid Conformation; Plasmids; Protein Kinases; Receptors, Cell Surface; RNA; RNA, Double-Stranded; RNA, Messenger; Signal Transduction; Staurosporine; Toll-Like Receptor 3; Toll-Like Receptors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2004 |
Bcl2-low-expressing MCF7 cells undergo necrosis rather than apoptosis upon staurosporine treatment.
Topics: Amino Acid Sequence; Apoptosis; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Chromatin; Clone Cells; Flow Cytometry; HMGB1 Protein; Humans; Molecular Sequence Data; Necrosis; Peptide Mapping; Proteome; Proto-Oncogene Proteins c-bcl-2; RNA, Catalytic; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staurosporine; Transfection | 2004 |
Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis.
Topics: Animals; Apoptosis; B-Lymphocytes; Calcium; Calcium Channels; Caspase 3; Caspases; Cell Death; Cell Membrane; Cerebellum; Chickens; Culture Media, Serum-Free; Cytosol; DNA; Enzyme Inhibitors; Flow Cytometry; Gene Deletion; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Mice; Microsomes; Mutation; Necrosis; Protein Structure, Tertiary; Receptors, Antigen, B-Cell; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Staurosporine; Time Factors; Transfection | 2004 |
Cathepsin B-independent abrogation of cell death by CA-074-OMe upstream of lysosomal breakdown.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Caspases; Cathepsin B; Cell Survival; Dipeptidases; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; HL-60 Cells; Humans; Intracellular Membranes; Lysosomes; Necrosis; Signal Transduction; Staurosporine | 2004 |
Differential role of hydrogen peroxide and staurosporine in induction of cell death in glioblastoma cells lacking DNA-dependent protein kinase.
Topics: Apoptosis; Brain Neoplasms; Cell Death; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Glioblastoma; Humans; Hydrogen Peroxide; Necrosis; Nuclear Proteins; Oxidants; Protein Serine-Threonine Kinases; Staurosporine | 2005 |
Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Caspase 9; Caspases; Cell Line; Cell Survival; Cloning, Molecular; Enzyme Inhibitors; Etoposide; Fibroblasts; Humans; Kinetics; Models, Genetic; Necrosis; Plasmids; Protein Structure, Tertiary; Rats; Retinoblastoma Protein; Staurosporine; Temperature; Tumor Suppressor Protein p53 | 2005 |
Regulatory and necrotic volume increase in boar spermatozoa.
Topics: Animals; Annexin A5; Cell Size; Chloride Channels; Enzyme Inhibitors; Hypertonic Solutions; Male; Necrosis; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Quinidine; Semen Preservation; Spermatozoa; Staining and Labeling; Staurosporine; Swine; Tamoxifen; Tyrosine; Vanadates | 2005 |
The role of macrophages in the in vitro generation of extracellular DNA from apoptotic and necrotic cells.
Topics: Animals; Apoptosis; Cell Death; Cell Line; Coculture Techniques; Culture Media; DNA; Etoposide; Humans; Jurkat Cells; Macrophages; Mice; Molecular Weight; Necrosis; Phagocytosis; Staurosporine | 2005 |
Early apoptotic and late necrotic components associated with altered Ca2+ homeostasis in a peptide-delivery model of polyglutamine-induced neuronal death.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Caspase 3; Caspase 7; Caspases; Cell Count; Cells, Cultured; Colforsin; Cyclin D1; Cycloheximide; Dihydrotachysterol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Homeostasis; Immunohistochemistry; In Situ Nick-End Labeling; Ionophores; Lactic Acid; Mitochondria; Models, Biological; Necrosis; Nerve Growth Factor; Neurons; Neuroprotective Agents; Peptides; Permeability; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Superior Cervical Ganglion; Time Factors | 2005 |
Monocyte viability on titanium and copper coated titanium.
Topics: Annexin A5; Apoptosis; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Death; Cell Survival; Centrifugation; Coated Materials, Biocompatible; Copper; Cytokines; Humans; Inflammation; Interleukin-10; Kinetics; L-Lactate Dehydrogenase; Monocytes; Necrosis; Propidium; Staurosporine; Surface Properties; Time Factors; Titanium; Tumor Necrosis Factor-alpha | 2005 |
A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type.
Topics: Alkenes; Alkylation; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Dactinomycin; Diploidy; DNA Fragmentation; DNA, Neoplasm; Enzyme Inhibitors; Lymphoma, T-Cell; Mice; Necrosis; Prodigiosin; Pyrroles; Rats; Sarcoma 180; Staurosporine; Tetrazolium Salts; Thiazoles | 2008 |
Cystein cathepsin and Hsp90 activities determine the balance between apoptotic and necrotic cell death pathways in caspase-compromised U937 cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Benzoquinones; Caspase Inhibitors; Caspases; Cathepsins; HSP90 Heat-Shock Proteins; Humans; Hydrogen Peroxide; Lactams, Macrocyclic; Lysosomes; Membrane Potential, Mitochondrial; Necrosis; Signal Transduction; Staurosporine; U937 Cells | 2007 |
Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis.
Topics: Apoptosis; Cell Size; HeLa Cells; Humans; Hypertonic Solutions; Ion Channels; Necrosis; Osmotic Pressure; Patch-Clamp Techniques; Staurosporine | 2008 |
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells.
Topics: Adjuvants, Immunologic; Animals; Antibodies, Monoclonal; Apoptosis; Dactinomycin; Enzyme Inhibitors; fas Receptor; Humans; Lithium Chloride; Mice; Necrosis; Nucleic Acid Synthesis Inhibitors; Serine Proteinase Inhibitors; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Noninvasive monitoring of apoptosis versus necrosis in a neuroblastoma cell line expressing a nuclear pore protein tagged with the green fluorescent protein.
Topics: Apoptosis; Benzoquinones; Biomarkers; Chromatin; DNA Fragmentation; Green Fluorescent Proteins; Humans; Luminescent Proteins; Membrane Proteins; Necrosis; Neuroblastoma; Nuclear Envelope; Nuclear Proteins; Recombinant Fusion Proteins; Staurosporine; Transfection; Tumor Cells, Cultured | 1998 |
A comparative study of different methods for the assessment of apoptosis and necrosis in human eosinophils.
Topics: Annexin A5; Apoptosis; Cell Death; Cell Membrane; Cells, Cultured; Cellular Senescence; DNA Fragmentation; Enzyme Inhibitors; Eosinophils; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-5; Membrane Lipids; Necrosis; Phosphatidylserines; Protein Kinase C; Staining and Labeling; Staurosporine | 1998 |
Pivotal role of mitochondrial calcium uptake in neural cell apoptosis and necrosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Calcium; Caspase 3; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Membrane Potentials; Mitochondria; Necrosis; Neurons; Oligopeptides; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species; Staurosporine | 1999 |
Poly(ADP ribose) polymerase cleavage precedes neuronal death in the hippocampus and cerebellum following injury to the developing rat forebrain.
Topics: 3T3 Cells; Age Factors; Animals; Apoptosis; Blotting, Western; Brain Ischemia; Caspases; Cerebellum; DNA Fragmentation; Enzyme Inhibitors; Hippocampus; Mice; Necrosis; Needles; Neuroblastoma; Neurons; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerases; Prosencephalon; Rats; Rats, Wistar; Sodium Azide; Staurosporine; Trypan Blue; Tumor Cells, Cultured; Wounds, Stab | 1999 |
Protection against necrosis but not apoptosis by heat-stress proteins in vascular smooth muscle cells: evidence for distinct modes of cell death.
Topics: Animals; Apoptosis; Cell Division; Cells, Cultured; Culture Media, Serum-Free; DNA Fragmentation; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Hypertension; Male; Muscle, Smooth, Vascular; Necrosis; Rats; Rats, Inbred BN; Rats, Inbred SHR; Staurosporine | 1999 |
Phosphatidylinositol 3-kinase-mediated regulation of neuronal apoptosis and necrosis by insulin and IGF-I.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Apoptosis; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Hypoglycemic Agents; Insulin; Insulin Antagonists; Insulin-Like Growth Factor I; Iron; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; N-Methylaspartate; Necrosis; Neocortex; Neurons; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorus Radioisotopes; Phosphorylation; Staurosporine; Wortmannin | 1999 |
Requirement for protein kinase C in reactive oxygen species-induced apoptosis of vascular smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Apoptosis; Cells, Cultured; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hydrogen Peroxide; Immunohistochemistry; In Situ Nick-End Labeling; Muscle, Smooth, Vascular; Naphthalenes; Necrosis; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Reactive Oxygen Species; Staurosporine; Tetradecanoylphorbol Acetate | 1999 |
Loss of cyclin D1 in necrotic and apoptotic models of cortical neuronal degeneration.
Topics: Animals; Apoptosis; Cell Cycle; Cells, Cultured; Cerebral Cortex; Cyclin D1; Fetus; G1 Phase; Glutamic Acid; Kinetics; Models, Neurological; Necrosis; Nerve Degeneration; Neurons; Rats; Resting Phase, Cell Cycle; S Phase; Staurosporine | 1999 |
Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Biological Transport; Caspase 3; Caspase 7; Caspases; Catalysis; Cell Survival; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Intracellular Membranes; Male; Mitochondria; Necrosis; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2000 |
Human Bcl-2 protects against AMPA receptor-mediated apoptosis.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Cells, Cultured; DNA; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Genotype; Glutamic Acid; Humans; Hydrogen Peroxide; Mice; Mice, Transgenic; Microscopy, Fluorescence; Necrosis; Neocortex; Neurons; Neurotoxins; Oxidants; Proto-Oncogene Proteins c-bcl-2; Receptors, AMPA; Staurosporine | 2000 |
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Inducing Factor; Biological Transport, Active; Caspases; Cell Line; Cell Nucleus; Chromatin; Cytochrome c Group; DNA Damage; Flavoproteins; Humans; Membrane Proteins; Microscopy, Confocal; Microscopy, Electron; Mitochondria; Models, Biological; Necrosis; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Rats; Staurosporine | 2000 |
Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro.
Topics: Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Etoposide; Models, Neurological; Necrosis; Neurons; Rats; Receptors, Metabotropic Glutamate; Staurosporine | 2000 |
Phagocytosis of nonapoptotic cells dying by caspase-independent mechanisms.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Biomarkers; Calcium; Caspases; Cell Death; Culture Media; Dose-Response Relationship, Drug; Humans; Jurkat Cells; Microglia; Necrosis; Phagocytosis; Phosphatidylserines; Rats; Rats, Wistar; Staurosporine | 2000 |
Melatonin is protective in necrotic but not in caspase-dependent, free radical-independent apoptotic neuronal cell death in primary neuronal cultures.
Topics: Animals; Antioxidants; Apoptosis; Aziridines; Caspase Inhibitors; Caspases; Cell Survival; Cells, Cultured; Choline; Cyclic N-Oxides; Drug Interactions; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Glucose; Hypoxia; Melatonin; Necrosis; Neurons; Nitrogen Oxides; Rats; Rats, Wistar; Staurosporine; Thiourea | 2000 |
Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes.
Topics: Angiotensin II; Animals; Animals, Newborn; Apoptosis; Camptothecin; Cell Nucleus; Cell Separation; Cells, Cultured; Chick Embryo; Culture Media, Serum-Free; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Heart; In Situ Nick-End Labeling; Mice; Myocardium; Necrosis; Propidium; Staurosporine; Tetrazolium Salts; Thiazoles; Time Factors | 2000 |
Differential effects of bcl-2 on cell death triggered under ATP-depleting conditions.
Topics: Adenosine Triphosphate; Apoptosis; Cytochrome c Group; Glutathione; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Necrosis; Nitric Oxide; Nitroso Compounds; Proto-Oncogene Proteins c-bcl-2; Rotenone; S-Nitrosoglutathione; Staurosporine; Time Factors | 2001 |
Calcitonin potentiates oxygen-glucose deprivation-induced neuronal death.
Topics: Animals; Apoptosis; Calcitonin; Cell Death; Cells, Cultured; Culture Media, Serum-Free; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glucose; Hypoxia-Ischemia, Brain; Kainic Acid; Mice; N-Methylaspartate; Necrosis; Neurons; Oxygen; Receptors, AMPA; Salmon; Staurosporine | 2001 |
Differential mechanisms of neuroprotection by 17 beta-estradiol in apoptotic versus necrotic neurodegeneration.
Topics: Animals; Apoptosis; Aziridines; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Choline; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Glucose; Glutamic Acid; Hippocampus; L-Lactate Dehydrogenase; Necrosis; Neurons; Neuroprotective Agents; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptors, Estrogen; Septum of Brain; Staurosporine; Time Factors | 2001 |
Caspase-independent cell death and mitochondrial disruptions observed in the Apaf1-deficient cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Apoptotic Protease-Activating Factor 1; Caspase Inhibitors; Caspases; Cell Death; Cell Membrane; Cell Nucleus; Cells, Cultured; Fibroblasts; Gene Deletion; Intracellular Membranes; Membrane Potentials; Mice; Microscopy, Electron; Microscopy, Fluorescence; Mitochondria; Necrosis; Proteins; Staurosporine; Time Factors | 2001 |
Cleavage of Bax is mediated by caspase-dependent or -independent calpain activation in dopaminergic neuronal cells: protective role of Bcl-2.
Topics: 1-Methyl-4-phenylpyridinium; Animals; bcl-2-Associated X Protein; Calpain; Caspases; Cell Death; Cell Line; Dopamine; Enzyme Inhibitors; Herbicides; Humans; Microscopy, Electron; Necrosis; Neurons; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 2001 |
The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours.
Topics: Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Line; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; Humans; Microscopy, Fluorescence; Mutation; Necrosis; Organ Specificity; Phagocytes; Phagocytosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2001 |
Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo.
Topics: Adult; Aged; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Biomarkers; Biomarkers, Tumor; Chick Embryo; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; Dactinomycin; Enzyme Inhibitors; Extracellular Space; Female; Hematologic Neoplasms; Humans; Hydrogen Peroxide; Jurkat Cells; L Cells; L-Lactate Dehydrogenase; Male; Mice; Middle Aged; Mitochondria; Necrosis; Neoplasm Proteins; Nucleic Acid Synthesis Inhibitors; Protein Transport; Staurosporine; Tumor Necrosis Factor-alpha | 2001 |
Chelerythrine rapidly induces apoptosis through generation of reactive oxygen species in cardiac myocytes.
Topics: Acetylcysteine; Adenoviridae; Alkaloids; Animals; Animals, Newborn; Annexin A5; Antioxidants; Apoptosis; Benzophenanthridines; Caspases; Cytosol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genetic Vectors; Glutathione; Hydrogen Peroxide; Immunoblotting; In Situ Nick-End Labeling; Injections, Intravenous; Microscopy, Fluorescence; Myocardium; Necrosis; Phenanthridines; Protein Isoforms; Protein Kinase C; Rats; Rats, Wistar; Reactive Oxygen Species; Staurosporine; Subcellular Fractions; Tetradecanoylphorbol Acetate; Time Factors | 2001 |
Secondary necrosis is a source of proteolytically modified forms of specific intracellular autoantigens: implications for systemic autoimmunity.
Topics: Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Apoptosis; Autoantigens; Caspases; DNA Topoisomerases, Type I; Drug Combinations; Etoposide; HeLa Cells; Humans; Jurkat Cells; Necrosis; Poly(ADP-ribose) Polymerases; Ribonucleoprotein, U1 Small Nuclear; Staurosporine | 2001 |
Cyclic AMP differentiation of the oligodendroglial cell line N20.1 switches staurosporine-induced cell death from necrosis to apoptosis.
Topics: Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Differentiation; Cell Line, Transformed; Cell Nucleus; Central Nervous System; Coloring Agents; Cyclic AMP; DNA Fragmentation; DNA, Single-Stranded; Enzyme Inhibitors; Humans; Multiple Sclerosis; Necrosis; Oligodendroglia; Propidium; Staurosporine; Temperature; Trypan Blue | 2001 |
Two-color, fluorescence-based microplate assay for apoptosis detection.
Topics: Animals; Apoptosis; Benzoxazoles; Blood Proteins; Cells, Cultured; Chickens; Color; Coloring Agents; Cytological Techniques; Enzyme Inhibitors; Fluorescent Dyes; Microscopy, Fluorescence; Necrosis; Neurons; Propidium; Quinolinium Compounds; Staurosporine | 2002 |
Mechanism of staurosporine-induced apoptosis in murine hepatocytes.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Caspases; Cell Survival; Cysteine Proteinase Inhibitors; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; Hepatocytes; Humans; Jurkat Cells; Male; Mice; Mice, Inbred C57BL; Mitochondria; Necrosis; NF-kappa B; Staurosporine; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2002 |
7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells.
Topics: Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Count; Cell Line; Cell Survival; Cytochrome c Group; Cytoskeleton; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Ketocholesterols; Necrosis; Staurosporine; Subcellular Fractions | 2002 |
Fragmentation of Golgi complex and Golgi autoantigens during apoptosis and necrosis.
Topics: Apoptosis; Autoantigens; Autoimmunity; Dose-Response Relationship, Drug; Fluorescent Antibody Technique, Indirect; Golgi Apparatus; Hepatocytes; Humans; Immunoblotting; Jurkat Cells; Membrane Proteins; Necrosis; Staurosporine | 2002 |