staurosporine has been researched along with Leukemia, Promyelocytic, Acute in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.35) | 18.7374 |
| 1990's | 18 (78.26) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, X; Ding, M; Liang, C; Sheng, Y; Weng, XQ; Wu, J | 1 |
| Cai, X; Ge, DZ; Sheng, Y | 1 |
| Drexler, HG; Meyer, C; Proksch, P; Schupp, P; Steube, KG | 1 |
| Kiyoi, H | 1 |
| Grant, S; Jarvis, WD; Povirk, LF; Traylor, RS; Turner, AJ | 1 |
| Bertrand, R; Jenkins, J; Pommier, Y; Solary, E | 1 |
| Arai, T; Irino, S; Kawanishi, K; Kiuchi, H; Takahara, J; Tanaka, T; Taoka, T; Yamaoka, G | 1 |
| Chan, KF; Loh, TT; Lok, CN | 1 |
| Björnberg, F; Gullberg, U; Lantz, M; Olsson, I | 1 |
| Bartimole, TM; Grant, S; Jarvis, WD; Joe, VC; Nelms, PA; Turner, AJ | 1 |
| Ali, A; Ford-Hutchinson, AW; Nicholson, DW | 1 |
| Biskobing, DM; Nanes, MS; Rubin, J | 1 |
| Kolb, H; Petrides, PE; Ries, C | 1 |
| Danishefsky, I; Whyzmuzis, CA; Wu, JM | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Chorváth, B; Duraj, J; Hunáková, L; Jayaram, HN; Kelley, MR; Novotný, L; Romanová, D; Sedlák, J; Szekeres, T | 1 |
| Mattera, R; Xing, M | 1 |
| Ishihara, H; Shikita, M; Takeuchi, K; Tsuneoka, K | 1 |
| Kato, Y; Ogawa, K; Okuda, T; Okuma, M; Sawada, H; Tashima, M; Yumoto, Y | 1 |
| Aigner, L; Brockhaus, M; Hohmann, HP; Remy, R; van Loon, AP | 1 |
| Tai, HH; Tian, ZG; Xun, CQ | 1 |
| Handschumacher, RE; Lee, CW; Sartorelli, AC; Sokoloski, JA | 1 |
| Komada, F; Nishikawa, M; Shirakawa, S; Uemura, Y | 1 |
23 other study(ies) available for staurosporine and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
The combination of UCN-01 and ATRA triggers differentiation in ATRA resistant acute promyelocytic leukemia cell lines via RAF-1 independent activation of MEK/ERK.
Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Leukemia, Promyelocytic, Acute; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-raf; Staurosporine; Tretinoin | 2019 |
Combined staurosporine and retinoic acid induces differentiation in retinoic acid resistant acute promyelocytic leukemia cell lines.
Topics: CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Granulocytes; Humans; Leukemia, Promyelocytic, Acute; Mitogen-Activated Protein Kinases; Oncogene Proteins, Fusion; Phosphorylation; Staurosporine; Tretinoin | 2014 |
Differential effects of staurosporine and its analogues on chemokine release by promyelocytic leukemia cell line NB-4.
Topics: Cell Division; Cell Survival; Chemokine CCL2; Chemokines; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Humans; Interleukin-8; Leukemia, Promyelocytic, Acute; Protein Kinase C; Staurosporine; Tumor Necrosis Factor-alpha | 2003 |
[The present status of, and problems with the development of FLT3 kinase inhibitors].
Topics: Adult; Cell Cycle Proteins; Chaperonins; Child; fms-Like Tyrosine Kinase 3; Humans; Leukemia; Leukemia, Promyelocytic, Acute; Mutation; Piperazines; Protein Kinase C; Protein-Tyrosine Kinases; Quinazolines; Staurosporine | 2006 |
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Anthracenes; Antineoplastic Agents; Apoptosis; Benzophenanthridines; Cell Differentiation; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Gossypol; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Naphthalenes; Perylene; Phenanthridines; Piperazines; Polycyclic Compounds; Protein Kinase C; Staurosporine; Time Factors; Tumor Cells, Cultured | 1994 |
Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Aminoquinolines; Aphidicolin; Apoptosis; Benzamides; Calcium; Calmodulin; Camptothecin; Cell Cycle; Chromatin; Cyclosporine; DNA; Egtazic Acid; Ethers, Cyclic; Humans; Isoquinolines; Leukemia, Experimental; Leukemia, Promyelocytic, Acute; Microscopy, Electron; Naphthalenes; Okadaic Acid; Phosphoprotein Phosphatases; Piperazines; Poly Adenosine Diphosphate Ribose; Poly(ADP-ribose) Polymerase Inhibitors; Polycyclic Compounds; Protein Kinase C; Spermine; Staurosporine; Teniposide; Tetradecanoylphorbol Acetate; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1993 |
Alkaline phosphatase activity in the human promyelocytic leukemia cell line, HL-60, induced by retinoic acid and recombinant human granulocyte colony-stimulating factor.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaline Phosphatase; Alkaloids; Calcitriol; Cell Line; Enzyme Induction; Granulocyte Colony-Stimulating Factor; Humans; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; Piperazines; Protein Kinase C; Recombinant Proteins; Staurosporine; Tretinoin; Tumor Cells, Cultured | 1993 |
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplasm; Enzyme Activation; Gene Expression; Humans; Indoles; Isoquinolines; Leukemia, Promyelocytic, Acute; Maleimides; Protein Kinase C; Protein Kinases; Receptors, Transferrin; RNA, Messenger; Staurosporine; Sulfonamides; Tetradecanoylphorbol Acetate; Thymidine; Tumor Cells, Cultured | 1995 |
Mechanisms involved in the processing of the p55 and the p75 tumor necrosis factor (TNF) receptors to soluble receptor forms.
Topics: Alkaloids; Ammonium Chloride; Bucladesine; Carrier Proteins; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endopeptidases; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Leukemia, Monocytic, Acute; Leukemia, Promyelocytic, Acute; Monensin; Neoplasm Proteins; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Solubility; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor Decoy Receptors | 1994 |
Modulation of 1-[beta-D-arabinofuranosyl] cytosine-induced apoptosis in human myeloid leukemia cells by staurosporine and other pharmacological inhibitors of protein kinase C.
Topics: Alkaloids; Apoptosis; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA Damage; Drug Synergism; Gene Expression; Genes, jun; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1994 |
Activation of protein kinase C down-regulates leukotriene C4 synthase activity and attenuates cysteinyl leukotriene production in an eosinophilic substrain of HL-60 cells.
Topics: Alkaloids; Calcimycin; Cysteine; Down-Regulation; Eosinophils; Glutathione Transferase; Humans; Leukemia, Promyelocytic, Acute; Leukotrienes; Nitriles; Phenols; Prostaglandins; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrphostins | 1994 |
1,25-Dihydroxyvitamin D3 and phorbol myristate acetate synergistically increase carbonic anhydrase-II expression in a human myelomonocytic cell line.
Topics: Alkaloids; Calcitriol; Carbonic Anhydrases; Drug Synergism; Gene Expression Regulation, Enzymologic; Humans; Leukemia, Promyelocytic, Acute; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Regulation of 92-kD gelatinase release in HL-60 leukemia cells: tumor necrosis factor-alpha as an autocrine stimulus for basal- and phorbol ester-induced secretion.
Topics: Alkaloids; Dexamethasone; Ditiocarb; Gelatinases; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Pentoxifylline; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Changes in proteoglycan core protein (PCP) mRNA levels during HL-60 cell differentiation.
Topics: Aggrecans; Alkaloids; Blotting, Northern; Cell Differentiation; Dimethyl Sulfoxide; Extracellular Matrix Proteins; Gene Expression; Genes, myc; Glycoproteins; Granulocytes; Humans; Kinetics; Lectins, C-Type; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Protein Kinase C; Proteoglycans; RNA, Messenger; RNA, Ribosomal, 18S; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Staurosporine enhanced benzamide riboside-induced apoptosis in human multidrug-resistant promyelocytic leukemia cells (HL-60/VCR) in vitro.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; DNA Fragmentation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; HL-60 Cells; Humans; IMP Dehydrogenase; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Nucleosides; Staurosporine | 1998 |
Phosphorylation-dependent regulation of phospholipase A2 by G-proteins and Ca2+ in HL60 granulocytes.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Alkaloids; Arachidonic Acid; Calcium; Egtazic Acid; Enzyme Activation; Granulocytes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Homeostasis; Humans; Isoflurophate; Kinetics; Leukemia, Promyelocytic, Acute; Models, Biological; Pertussis Toxin; Phosphorylation; Protein Kinase C; Ribonucleotides; Staurosporine; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1992 |
Barbiturates enhance retinoic acid or 1,25-dihydroxyvitamin D3-induced differentiation of leukemia HL-60 cells.
Topics: Alkaloids; Barbiturates; Bucladesine; Calcitriol; Cell Differentiation; Cell Line; Dactinomycin; Dimethyl Sulfoxide; Granulocytes; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Macrophages; Monocytes; Pentobarbital; Protein Kinase C; Staurosporine; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tretinoin | 1991 |
Effects of protein kinase A and calcium/phospholipid-dependent kinase modulators in the process of HL-60 cell differentiation: their opposite effects between HL-60 cell and K-562 cell differentiation.
Topics: Alkaloids; Calcium; Cell Differentiation; Cell Line; Cholecalciferol; Diglycerides; Enzyme Activation; Gene Expression Regulation; Isoquinolines; Leukemia, Promyelocytic, Acute; Magnesium; Muramidase; Phenotype; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1991 |
Protein kinases negatively affect nuclear factor-kappa B activation by tumor necrosis factor-alpha at two different stages in promyelocytic HL60 cells.
Topics: Alkaloids; Blotting, Northern; Cell Line; Cell Nucleus; Cytosol; Humans; Interleukin-1; Kinetics; Leukemia, Promyelocytic, Acute; Macromolecular Substances; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Recombinant Proteins; RNA, Messenger; RNA, Neoplasm; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1992 |
Stimulation of synthesis de novo of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase in human promyelocytic leukaemia (HL-60) cells by phorbol ester.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Blotting, Western; Dimethyl Sulfoxide; Dinoprostone; Enzyme Activation; Enzyme Induction; Humans; Hydroxyprostaglandin Dehydrogenases; Isoquinolines; Kinetics; Leukemia, Promyelocytic, Acute; NAD; Piperazines; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |
Induction of the differentiation of HL-60 cells by phorbol 12-myristate 13-acetate activates a Na(+)-dependent uridine-transport system. Involvement of protein kinase C.
Topics: Alkaloids; Biological Transport; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Promyelocytic, Acute; Protein Kinase C; Ribonucleosides; Sodium; Staurosporine; Tetradecanoylphorbol Acetate; Uridine | 1991 |
Alteration of intracellular actin levels induced by phorboldiester in human HL-60 leukemia cells susceptible or resistant to differentiation, and the effects of protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Alkaloids; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cell Differentiation; Cell Line; Cytoplasm; Drug Resistance; Humans; Isoquinolines; Leukemia, Promyelocytic, Acute; Macrophages; Neoplasm Proteins; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1989 |