staurosporine and Innate Inflammatory Response

Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors

Topics: Aging; Animals; Congresses as Topic; DNA Mutational Analysis; Humans; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mastocytosis; Medical Oncology; Mice; Mutation; Myeloproliferative Disorders; Prognosis; Societies, Medical; Staurosporine; Translational Research, Biomedical; United States

Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Survival; Dose-Response Relationship, Drug; Inflammation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; RAW 264.7 Cells; Receptors, Colony-Stimulating Factor; Structure-Activity Relationship

Topics: Drug Discovery; Inflammation; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Nitric Oxide; Protein Kinase Inhibitors; Quinones; Spiro Compounds; Structure-Activity Relationship

Topics: Animals; Apoptosis; Cells, Cultured; Fibroblast Growth Factors; Hydrogen Peroxide; Inflammation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Oxidative Stress; Staurosporine; Tumor Necrosis Factor-alpha

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Line; Cytokines; Gene Expression Profiling; Gene Knockdown Techniques; Inflammation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Peptide Fragments; Proto-Oncogene Proteins; Rotenone; Staurosporine; Trans-Activators; Uncoupling Agents

Topics: Animals; Cervical Cord; Female; Inflammation; Neuroprotective Agents; Protein Kinase Inhibitors; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Staurosporine

Topics: Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; E-Selectin; Gene Knockdown Techniques; Genes, fos; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Mechanistic Target of Rapamycin Complex 2; Protein Kinase C; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; RNA, Small Interfering; Signal Transduction; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate

Topics: Animals; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Mice; NF-E2-Related Factor 2; Peroxiredoxins; Protein Kinase C; RAW 264.7 Cells; Reactive Oxygen Species; Staurosporine; Thioredoxin Reductase 1; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptor 7

Topics: Aminopropionitrile; Animals; Aortic Dissection; Apoptosis; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Jurkat Cells; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Scavenger Receptors, Class A; Staurosporine

Topics: Apoptosis; Case-Control Studies; Caspases; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neutrophils; Prospective Studies; Proteasome Endopeptidase Complex; Proteolysis; Signal Transduction; Staurosporine

Topics: Animals; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Interleukin-4; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Knockout; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; STAT6 Transcription Factor; Staurosporine; Tumor Suppressor Proteins; TYK2 Kinase

Topics: Amino Acid Substitution; Anticoagulants; Apoptosis; Cells, Cultured; Cytoprotection; Endothelial Cells; Enzyme Inhibitors; Glycosylation; Humans; Inflammation; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Protein C; Receptor, PAR-1; Signal Transduction; Staurosporine; Thrombin; Thrombosis

Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspases; Cell Death; Cells, Cultured; Cytokines; Enzyme Inhibitors; Inflammation; Insulin; Insulin-Secreting Cells; Insulinoma; Interferon-gamma; Interleukin-1beta; Metabolomics; NF-kappa B; Pancreatic Neoplasms; Rats; Signal Transduction; Staurosporine; Tandem Mass Spectrometry

Topics: Alternative Splicing; Apoptosis; Down-Regulation; Humans; Inflammation; Interleukin-1; Interleukin-1 Receptor Accessory Protein; Molecular Sequence Data; Phorbol Esters; Protein Isoforms; Protein Structure, Tertiary; Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Staurosporine; Stress, Physiological; Tumor Cells, Cultured

Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Apoptosis; Carrier Proteins; Dose-Response Relationship, Immunologic; Enzyme Activation; Female; Genetic Predisposition to Disease; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Listeria; Lymphocyte Subsets; Male; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 25; Receptors, Tumor Necrosis Factor, Type I; Reference Values; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha

Topics: Animals; Annexin A5; Antibodies, Monoclonal; Apoptosis; Calcium; CD36 Antigens; Cell Line; Cell Membrane; Cells, Cultured; Escherichia coli; Formaldehyde; Humans; Inflammation; Ionomycin; Jumonji Domain-Containing Histone Demethylases; Jurkat Cells; Lipopolysaccharide Receptors; Liposomes; Macrophages; Membrane Lipids; Mice; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Necrosis; Oligomycins; Oligopeptides; Phagocytosis; Phosphatidylserines; Polymers; Receptors, Cell Surface; Staurosporine; Tumor Necrosis Factor-alpha

Topics: Alitretinoin; Anilides; Animals; Anti-Inflammatory Agents; Apoptosis; Astrocytes; Brain; Cell Death; Cell Line; Cell-Free System; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; In Vitro Techniques; Inflammation; Interleukin-6; Lipopolysaccharides; Lithium Chloride; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neurodegenerative Diseases; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Rats; Staurosporine; Thiazolidinediones; Time Factors; Transfection; Tretinoin; Tumor Necrosis Factor-alpha

Topics: Annexin A5; Apoptosis; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Death; Cell Survival; Centrifugation; Coated Materials, Biocompatible; Copper; Cytokines; Humans; Inflammation; Interleukin-10; Kinetics; L-Lactate Dehydrogenase; Monocytes; Necrosis; Propidium; Staurosporine; Surface Properties; Time Factors; Titanium; Tumor Necrosis Factor-alpha

Topics: Animals; Blotting, Northern; Blotting, Western; Brain; Cell Death; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; High Mobility Group Proteins; HMGB1 Protein; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Microglia; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Time Factors; Transfection

Topics: Animals; Aprotinin; Ascitic Fluid; Disease Models, Animal; Inflammation; Interleukin-10; Lung; Male; Neutrophils; Pancreas; Pancreatitis; Peptide Hydrolases; Peroxidase; Phospholipases A; Polymyxin B; Protease Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Staurosporine; Sulfones; Taurodeoxycholic Acid; Time Factors; Trypsin Inhibitors

Topics: Animals; Carcinogens; Cells, Cultured; Dimerization; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1-beta; Humans; Inflammation; MafG Transcription Factor; Male; Mutation; Naphthalenes; Nitric Oxide Synthase Type II; Protein Kinase C; Rats; Rats, Sprague-Dawley; Repressor Proteins; Response Elements; RNA, Small Interfering; Signal Transduction; Smad6 Protein; Smad7 Protein; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Inflammation; Inhibins; Interleukin-2; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; Tyrphostins

Topics: Antibodies; Antibody Specificity; Cell-Free System; Cells, Cultured; Cytokines; Eukaryotic Initiation Factor-4E; Fibroblasts; Fluorescent Antibody Technique; HeLa Cells; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mitogens; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Skin; Staurosporine; Time Factors

Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate