Page last updated: 2024-08-23

staurosporine and Inflammation

staurosporine has been researched along with Inflammation in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's1 (4.00)18.2507
2000's10 (40.00)29.6817
2010's10 (40.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Hoda, N; Maqbool, M; Mobashir, M1
Elkamhawy, A; Farag, AK; Lee, KT; Londhe, AM; Pae, AN; Roh, EJ1
Cho, KH; Dhorma, LP; Hah, JM; Kim, MH; Kim, SY; Kumar, DN; Park, HG; Venkanna, A1
Chuang, DM; Leng, Y; Linares, GR; Maric, D1
Bowles, KR; Goate, AM; Gupta, I; Herbinet, M; Machlovi, SI; Marcora, E; Pimenova, AA1
Badner, A; Chio, JCT; Fehlings, MG; Hong, J; Khazaei, M; Wang, J; Zavvarian, MM1
Cao, YJ; Du, WX; Huang, YB; Liu, CF; Liu, HH; Shi, LY; Sun, JJ; Wang, F; Yin, XW; Zhang, YL1
Ghezzi, P; Ingram, S; Mengozzi, M; Mullen, L; Sacre, S1
Barbui, T; Bose, P; Chen, CC; Deininger, MW; Gotlib, J; Kiladjian, JJ; Koschmieder, S; Kucine, N; Mughal, TI; Pemmaraju, N; Radich, JP; Rampal, R; Saglio, G; Valent, P; Van Etten, RA; Verstovsek, S1
Bai, H; Ben, J; Chen, Q; Chen, S; Huang, J; Jiang, Y; Li, X; Yang, Q; Zhang, H; Zhang, Z; Zhou, W; Zhou, Z; Zhu, X1
Detmer, S; Flohé, S; Hoffmann, M; Hornstein, T; Lehmann, S; Paunel-Görgülü, A; Peter, C; Philipp, D; Unfried, K; Wesselborg, S; Windolf, J1
Jiang, X; Lossos, IS; Lu, X; Malumbres, R; Natkunam, Y; Sarosiek, KA; Shields, B; Tiganis, T1
Brown, L; Gleeson, EM; Johnson, JA; Ní Ainle, F; O'Donnell, JS; Preston, RJ; Smith, OP1
Burke, SJ; Campagna, SR; Collier, JJ; Eisenhauer, ME; Frydman, CJ; Lu, D; Sapp, RC1
Jensen, LE; Whitehead, AS1
Brosch, I; Endres, R; Häcker, G; Pfeffer, K1
Hirt, UA; Leist, M1
Alonso, M; Cortes-Canteli, M; Luna-Medina, R; Martínez, A; Perez-Castillo, A; Santos, A1
Esposito, M; Gretzer, C; Suska, F; Tengvall, P; Thomsen, P1
Han, PL; Kim, JB; Kim, SW; Lee, JK; Lee, MH; Nam, K; Park, JS; Piao, CS; Sig Choi, J; Yu, YM1
Andersson, R; Shi, C; Wang, X; Zhao, L; Zhao, X1
Berg, DT; Calnek, D; Grinnell, BW; Gupta, A; O'Brien, LA; Richardson, MA1
Barsig, J; Nüsing, RM1
Brauchle, M; Glueck, D; Gram, H; Han, J; Knauf, U; New, L; Ramage, P; Tschopp, C; Zurini, M1
Aizu, E; Hosoda, Y; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S1

Reviews

2 review(s) available for staurosporine and Inflammation

ArticleYear
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
    European journal of medicinal chemistry, 2016, Jan-01, Volume: 107

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors

2016
Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms.
    Hematological oncology, 2019, Volume: 37, Issue:3

    Topics: Aging; Animals; Congresses as Topic; DNA Mutational Analysis; Humans; Inflammation; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mastocytosis; Medical Oncology; Mice; Mutation; Myeloproliferative Disorders; Prognosis; Societies, Medical; Staurosporine; Translational Research, Biomedical; United States

2019

Other Studies

23 other study(ies) available for staurosporine and Inflammation

ArticleYear
Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders.
    European journal of medicinal chemistry, 2017, Dec-01, Volume: 141

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Survival; Dose-Response Relationship, Drug; Inflammation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Molecular Docking Simulation; Molecular Structure; Protein Kinase Inhibitors; Pyrimidines; RAW 264.7 Cells; Receptors, Colony-Stimulating Factor; Structure-Activity Relationship

2017
Chemistry-oriented synthesis (ChOS) and target deconvolution on neuroprotective effect of a novel scaffold, oxaza spiroquinone.
    European journal of medicinal chemistry, 2019, Feb-01, Volume: 163

    Topics: Drug Discovery; Inflammation; Microglia; Neurodegenerative Diseases; Neuroprotective Agents; Nitric Oxide; Protein Kinase Inhibitors; Quinones; Spiro Compounds; Structure-Activity Relationship

2019
Overexpression of fibroblast growth factor-21 (FGF-21) protects mesenchymal stem cells against caspase-dependent apoptosis induced by oxidative stress and inflammation.
    Cell biology international, 2020, Volume: 44, Issue:10

    Topics: Animals; Apoptosis; Cells, Cultured; Fibroblast Growth Factors; Hydrogen Peroxide; Inflammation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Oxidative Stress; Staurosporine; Tumor Necrosis Factor-alpha

2020
Alzheimer's-associated PU.1 expression levels regulate microglial inflammatory response.
    Neurobiology of disease, 2021, Volume: 148

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Line; Cytokines; Gene Expression Profiling; Gene Knockdown Techniques; Inflammation; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Peptide Fragments; Proto-Oncogene Proteins; Rotenone; Staurosporine; Trans-Activators; Uncoupling Agents

2021
The Protein Kinase Inhibitor Midostaurin Improves Functional Neurological Recovery and Attenuates Inflammatory Changes Following Traumatic Cervical Spinal Cord Injury.
    Biomolecules, 2021, 07-01, Volume: 11, Issue:7

    Topics: Animals; Cervical Cord; Female; Inflammation; Neuroprotective Agents; Protein Kinase Inhibitors; Rats; Rats, Wistar; Recovery of Function; Spinal Cord Injuries; Staurosporine

2021
Rapamycin inhibits ox-LDL-induced inflammation in human endothelial cells in vitro by inhibiting the mTORC2/PKC/c-Fos pathway.
    Acta pharmacologica Sinica, 2018, Volume: 39, Issue:3

    Topics: Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; E-Selectin; Gene Knockdown Techniques; Genes, fos; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Intercellular Adhesion Molecule-1; Lipoproteins, LDL; Mechanistic Target of Rapamycin Complex 2; Protein Kinase C; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; RNA, Small Interfering; Signal Transduction; Sirolimus; Staurosporine; Tetradecanoylphorbol Acetate

2018
Differential induction of nuclear factor-like 2 signature genes with toll-like receptor stimulation.
    Free radical biology & medicine, 2019, 05-01, Volume: 135

    Topics: Animals; Gene Expression Regulation; Heme Oxygenase-1; Inflammation; Lipopolysaccharides; Membrane Glycoproteins; Membrane Proteins; Mice; NF-E2-Related Factor 2; Peroxiredoxins; Protein Kinase C; RAW 264.7 Cells; Reactive Oxygen Species; Staurosporine; Thioredoxin Reductase 1; Toll-Like Receptor 2; Toll-Like Receptor 3; Toll-Like Receptor 4; Toll-Like Receptor 7

2019
Scavenger receptor A1 attenuates aortic dissection via promoting efferocytosis in macrophages.
    Biochemical pharmacology, 2019, Volume: 168

    Topics: Aminopropionitrile; Animals; Aortic Dissection; Apoptosis; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Inflammation; Jurkat Cells; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Scavenger Receptors, Class A; Staurosporine

2019
Staurosporine resistance in inflammatory neutrophils is associated with the inhibition of caspase- and proteasome-mediated Mcl-1 degradation.
    Journal of leukocyte biology, 2016, Volume: 99, Issue:1

    Topics: Apoptosis; Case-Control Studies; Caspases; Drug Resistance; Enzyme Activation; Enzyme Inhibitors; Humans; Inflammation; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Neutrophils; Prospective Studies; Proteasome Endopeptidase Complex; Proteolysis; Signal Transduction; Staurosporine

2016
PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling.
    Blood, 2008, Nov-15, Volume: 112, Issue:10

    Topics: Animals; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; HeLa Cells; Humans; Inflammation; Interleukin-4; Lymphoma, Large B-Cell, Diffuse; Mice; Mice, Knockout; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; RNA, Messenger; Signal Transduction; STAT5 Transcription Factor; STAT6 Transcription Factor; Staurosporine; Tumor Suppressor Proteins; TYK2 Kinase

2008
Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells.
    The Journal of biological chemistry, 2011, Jan-14, Volume: 286, Issue:2

    Topics: Amino Acid Substitution; Anticoagulants; Apoptosis; Cells, Cultured; Cytoprotection; Endothelial Cells; Enzyme Inhibitors; Glycosylation; Humans; Inflammation; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Polysaccharides; Protein C; Receptor, PAR-1; Signal Transduction; Staurosporine; Thrombin; Thrombosis

2011
Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Caspases; Cell Death; Cells, Cultured; Cytokines; Enzyme Inhibitors; Inflammation; Insulin; Insulin-Secreting Cells; Insulinoma; Interferon-gamma; Interleukin-1beta; Metabolomics; NF-kappa B; Pancreatic Neoplasms; Rats; Signal Transduction; Staurosporine; Tandem Mass Spectrometry

2011
Expression of alternatively spliced interleukin-1 receptor accessory protein mRNAs is differentially regulated during inflammation and apoptosis.
    Cellular signalling, 2003, Volume: 15, Issue:8

    Topics: Alternative Splicing; Apoptosis; Down-Regulation; Humans; Inflammation; Interleukin-1; Interleukin-1 Receptor Accessory Protein; Molecular Sequence Data; Phorbol Esters; Protein Isoforms; Protein Structure, Tertiary; Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Staurosporine; Stress, Physiological; Tumor Cells, Cultured

2003
Apparently normal tumor necrosis factor receptor 1 signaling in the absence of the silencer of death domains.
    Molecular and cellular biology, 2003, Volume: 23, Issue:18

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Apoptosis; Carrier Proteins; Dose-Response Relationship, Immunologic; Enzyme Activation; Female; Genetic Predisposition to Disease; Heat-Shock Response; HSP70 Heat-Shock Proteins; Humans; Inflammation; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Listeria; Lymphocyte Subsets; Male; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Member 25; Receptors, Tumor Necrosis Factor, Type I; Reference Values; Signal Transduction; Staurosporine; Tumor Necrosis Factor-alpha

2003
Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells.
    Cell death and differentiation, 2003, Volume: 10, Issue:10

    Topics: Animals; Annexin A5; Antibodies, Monoclonal; Apoptosis; Calcium; CD36 Antigens; Cell Line; Cell Membrane; Cells, Cultured; Escherichia coli; Formaldehyde; Humans; Inflammation; Ionomycin; Jumonji Domain-Containing Histone Demethylases; Jurkat Cells; Lipopolysaccharide Receptors; Liposomes; Macrophages; Membrane Lipids; Mice; Microglia; Microscopy, Confocal; Microscopy, Fluorescence; Necrosis; Oligomycins; Oligopeptides; Phagocytosis; Phosphatidylserines; Polymers; Receptors, Cell Surface; Staurosporine; Tumor Necrosis Factor-alpha

2003
Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Alitretinoin; Anilides; Animals; Anti-Inflammatory Agents; Apoptosis; Astrocytes; Brain; Cell Death; Cell Line; Cell-Free System; Cells, Cultured; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutamic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Immunohistochemistry; In Vitro Techniques; Inflammation; Interleukin-6; Lipopolysaccharides; Lithium Chloride; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neurodegenerative Diseases; Neuroglia; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; PPAR gamma; Prostaglandin-Endoperoxide Synthases; Rats; Staurosporine; Thiazolidinediones; Time Factors; Transfection; Tretinoin; Tumor Necrosis Factor-alpha

2005
Monocyte viability on titanium and copper coated titanium.
    Biomaterials, 2005, Volume: 26, Issue:30

    Topics: Annexin A5; Apoptosis; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Death; Cell Survival; Centrifugation; Coated Materials, Biocompatible; Copper; Cytokines; Humans; Inflammation; Interleukin-10; Kinetics; L-Lactate Dehydrogenase; Monocytes; Necrosis; Propidium; Staurosporine; Surface Properties; Time Factors; Titanium; Tumor Necrosis Factor-alpha

2005
HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jun-14, Volume: 26, Issue:24

    Topics: Animals; Blotting, Northern; Blotting, Western; Brain; Cell Death; Cells, Cultured; Culture Media, Conditioned; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; High Mobility Group Proteins; HMGB1 Protein; Infarction, Middle Cerebral Artery; Inflammation; Male; Mice; Microglia; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Time Factors; Transfection

2006
Potential effects of PKC or protease inhibitors on acute pancreatitis-induced tissue injury in rats.
    Vascular pharmacology, 2007, Volume: 46, Issue:6

    Topics: Animals; Aprotinin; Ascitic Fluid; Disease Models, Animal; Inflammation; Interleukin-10; Lung; Male; Neutrophils; Pancreas; Pancreatitis; Peptide Hydrolases; Peroxidase; Phospholipases A; Polymyxin B; Protease Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Staurosporine; Sulfones; Taurodeoxycholic Acid; Time Factors; Trypsin Inhibitors

2007
Negative regulation of inducible nitric-oxide synthase expression mediated through transforming growth factor-beta-dependent modulation of transcription factor TCF11.
    The Journal of biological chemistry, 2007, Dec-21, Volume: 282, Issue:51

    Topics: Animals; Carcinogens; Cells, Cultured; Dimerization; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hepatocyte Nuclear Factor 1-beta; Humans; Inflammation; MafG Transcription Factor; Male; Mutation; Naphthalenes; Nitric Oxide Synthase Type II; Protein Kinase C; Rats; Rats, Sprague-Dawley; Repressor Proteins; Response Elements; RNA, Small Interfering; Signal Transduction; Smad6 Protein; Smad7 Protein; Staurosporine; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta1

2007
Inflammatory potency of activin A. Effect on prostanoid and nitric oxide formation.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Activins; Animals; Bone Marrow Cells; Cell Differentiation; Cinnamates; Cyclooxygenase 2; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Genistein; Inflammation; Inhibins; Interleukin-2; Isoenzymes; Lipopolysaccharides; Macrophages; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Necrosis Factor-alpha; Tyrphostins

1997
Phosphorylation of eIF-4E on Ser 209 in response to mitogenic and inflammatory stimuli is faithfully detected by specific antibodies.
    Molecular cell biology research communications : MCBRC, 2000, Volume: 3, Issue:4

    Topics: Antibodies; Antibody Specificity; Cell-Free System; Cells, Cultured; Cytokines; Eukaryotic Initiation Factor-4E; Fibroblasts; Fluorescent Antibody Technique; HeLa Cells; Humans; Inflammation; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mitogens; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphorylation; Phosphoserine; Protein Serine-Threonine Kinases; Skin; Staurosporine; Time Factors

2000
Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
    Carcinogenesis, 1989, Volume: 10, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate

1989