Compounds > staurosporine
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staurosporine and Genome Instability

staurosporine has been researched along with Genome Instability in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cotter, TG; Russell, EG; Stanicka, J; Woolley, JF1
Ahmed, SU; Athineos, D; Blyth, K; Bouchier-Hayes, L; Chalmers, AJ; Delgado, ME; Giampazolias, E; Haller, M; Ichim, G; Lopez, J; Mason, SM; Murphy, DJ; Muthalagu, N; Oberst, A; Parsons, MJ; Rehm, M; Riley, JS; Rooswinkel, RW; Tait, SWG; van de Kooij, B1
Lam, MH; Papineni, R; Peddibhotla, S; Rosen, JM; Wei, Z; Zhang, P1
Blain, SW; Ye, W1
Chen, Y; Chow, JP; Poon, RY1

Other Studies

5 other study(ies) available for staurosporine and Genome Instability

ArticleYear
NADPH oxidase-generated hydrogen peroxide induces DNA damage in mutant FLT3-expressing leukemia cells.
    The Journal of biological chemistry, 2015, Apr-10, Volume: 290, Issue:15

    Topics: Acute Disease; Animals; Blotting, Western; Cell Line; DNA Damage; fms-Like Tyrosine Kinase 3; Genomic Instability; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia, Myeloid; Mice; Microscopy, Confocal; Mutation; NADPH Oxidase 4; NADPH Oxidases; Protein Kinase Inhibitors; RNA Interference; Signal Transduction; Staurosporine; Tandem Repeat Sequences

2015
Limited mitochondrial permeabilization causes DNA damage and genomic instability in the absence of cell death.
    Molecular cell, 2015, Mar-05, Volume: 57, Issue:5

    Topics: Animals; Apoptosis; Biphenyl Compounds; Blotting, Western; Caspases; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p19; DNA Damage; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Genomic Instability; HCT116 Cells; HeLa Cells; Histones; Humans; MCF-7 Cells; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Mitochondrial Membranes; Nitrophenols; Permeability; Piperazines; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Sulfonamides; Time Factors

2015
The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression.
    Cell cycle (Georgetown, Tex.), 2011, Feb-15, Volume: 10, Issue:4

    Topics: Blotting, Western; Cell Cycle; Cell Line; Cell Nucleolus; Checkpoint Kinase 1; Chromosomal Proteins, Non-Histone; Chromosomes, Human; DNA Damage; Dual-Specificity Phosphatases; Genomic Instability; HeLa Cells; Humans; Immunoblotting; Immunoprecipitation; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA Interference; RNA, Small Interfering; Staurosporine

2011
Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:5

    Topics: Animals; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Caffeine; Camptothecin; Cell Cycle Proteins; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebral Cortex; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA Damage; DNA-Binding Proteins; Female; Genes, p53; Genomic Instability; Neurons; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Tumor Suppressor Proteins

2011
Inhibition of Eg5 acts synergistically with checkpoint abrogation in promoting mitotic catastrophe.
    Molecular cancer research : MCR, 2012, Volume: 10, Issue:5

    Topics: Apoptosis; Cell Cycle Checkpoints; Checkpoint Kinase 1; DNA Damage; Gene Expression Regulation; Genomic Instability; HCT116 Cells; HeLa Cells; Humans; Kinesins; M Phase Cell Cycle Checkpoints; Mitosis; Protein Kinases; Pyrimidines; Radiation, Ionizing; RNA, Small Interfering; Staurosporine; Thiones

2012