staurosporine has been researched along with Disease Exacerbation in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (61.54) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, H; Guo, X; Han, B; Hong, X; Jiang, W; Liu, K; Lu, S; Qiu, F; Qiu, X; Qu, L; Shi, T; Tian, L; Wu, Z; Yao, K; Zhao, J; Zhao, W; Zhong, L; Zhong, M; Zhou, B | 1 |
| Akin, C; Awan, FT; George, TI; Gotlib, J; Hartmann, K; Hermine, O; Hexner, E; Horny, HP; Kluin-Nelemans, HC; Knoll, S; Mauro, MJ; Menssen, HD; Redhu, S; Reiter, A; Sotlar, K; Valent, P | 1 |
| Agarwala, SS; Christensen, SD; Frankel, PH; Gandara, DR; Lara, PN; Li, T; Luu, T; Mack, PC; Margolin, KA | 1 |
| Alemu, L; Anderson, S; Brinster, L; Gilliland, DG; Hoogstraten-Miller, S; Kamikubo, Y; Kench, M; Kirby, M; Liu, PP; Melenhorst, JJ; Zhao, L | 1 |
| Pardanani, A | 1 |
| Angelini, A; Calvani, M; Dalla Libera, L; Della Barbera, M; Dona, M; Gobbo, V; Mosconi, L; Peluso, G; Ravara, B; Sandri, M; Vescovo, G | 1 |
| Ho, YS; Lee, WS; Liang, YC; Lin, SY; Pan, S; Tsai, SH | 1 |
| Gallick, GE; Kraker, AJ; McConkey, DJ; Parikh, NU; Siwak, DR; Summy, JM; Windham, TC | 1 |
| Amornphimoltham, P; Benavides, F; Conti, CJ; Gutkind, JS; Molinolo, AA; Patel, V; Sauk, J; Sausville, EA; Sriuranpong, V | 1 |
| Bok, R; Park, JW; Rini, BI; Scott, J; Shaw, V; Small, EJ; Weinberg, V | 1 |
| Shi, HY; Zhang, M; Zhang, W | 1 |
| Beaulieu, B; Beelen, AP; Eastman, A; Ernstoff, MS; Johnston, N; Lewis, LD; Olszanski, AJ; Perez, RP; Rhodes, CH | 1 |
| Bui, B; Italiano, A | 1 |
2 review(s) available for staurosporine and Disease Exacerbation
| Article | Year |
|---|---|
Systemic mastocytosis in adults: 2012 Update on diagnosis, risk stratification, and management.
Topics: Adrenal Cortex Hormones; Adult; Bone Marrow Examination; Cell Lineage; Cladribine; Clinical Trials as Topic; Clone Cells; Disease Management; Disease Progression; Humans; Hydroxyurea; Immunophenotyping; Interferon-alpha; Leukemia, Mast-Cell; Mast Cells; Mastocytosis, Systemic; Mutation, Missense; Organ Specificity; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Risk Assessment; Staurosporine; Tryptases | 2012 |
[Gastrointestinal stromal tumors: molecular aspects and therapeutic implications].
Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Proteins; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sorafenib; Staurosporine; Sunitinib; Thiazoles | 2008 |
4 trial(s) available for staurosporine and Disease Exacerbation
| Article | Year |
|---|---|
Midostaurin improves quality of life and mediator-related symptoms in advanced systemic mastocytosis.
Topics: Adult; Aged; Aged, 80 and over; Disease Progression; Female; Humans; Male; Mast Cells; Mastocytosis, Systemic; Middle Aged; Protein Kinase Inhibitors; Quality of Life; Staurosporine; Treatment Outcome | 2020 |
A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; California; Cell Cycle; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Melanoma; Middle Aged; Protein Kinase C; Protein Kinase Inhibitors; Skin Neoplasms; Staurosporine; Time Factors; Treatment Outcome | 2012 |
Time to disease progression to evaluate a novel protein kinase C inhibitor, UCN-01, in renal cell carcinoma.
Topics: Adult; Aged; Antigens, Neoplasm; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Adhesion Molecules; Disease Progression; Epithelial Cell Adhesion Molecule; Female; Flow Cytometry; Humans; Immunohistochemistry; Kidney Neoplasms; Male; Middle Aged; Neoplastic Cells, Circulating; Staurosporine; Time Factors; Treatment Outcome | 2004 |
Modulation of cell cycle progression in human tumors: a pharmacokinetic and tumor molecular pharmacodynamic study of cisplatin plus the Chk1 inhibitor UCN-01 (NSC 638850).
Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy, Fine-Needle; Cell Cycle; Cisplatin; Disease Progression; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Humans; Injections, Intravenous; Maximum Tolerated Dose; Neoplasms; Predictive Value of Tests; Staurosporine; Tissue Distribution; Treatment Outcome | 2006 |
7 other study(ies) available for staurosporine and Disease Exacerbation
| Article | Year |
|---|---|
PLK1/NF-κB feedforward circuit antagonizes the mono-ADP-ribosyltransferase activity of PARP10 and facilitates HCC progression.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Cell Cycle Proteins; Disease Progression; Feedback, Physiological; Female; HEK293 Cells; Hepatectomy; Humans; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Male; Mice; Middle Aged; Mutagenesis, Site-Directed; Neoplasm Staging; Nitriles; Phosphorylation; Polo-Like Kinase 1; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Signal Transduction; Staurosporine; Sulfones; Transcription Factor RelA; Xenograft Model Antitumor Assays | 2020 |
KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice.
Topics: Animals; Blotting, Western; Bone Marrow Transplantation; Cell Survival; Cells, Cultured; Disease Progression; Female; Flow Cytometry; Green Fluorescent Proteins; Humans; Leukemia; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins, Fusion; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Staurosporine | 2012 |
L-Carnitine: a potential treatment for blocking apoptosis and preventing skeletal muscle myopathy in heart failure.
Topics: Angiotensin II; Animals; Apoptosis; Carnitine; Caspase 3; Caspase 9; Caspases; Cell Nucleus; Cells, Cultured; Cytoprotection; Disease Models, Animal; Disease Progression; Drug Evaluation, Preclinical; Glucose Transporter Type 4; Heart Failure; In Situ Nick-End Labeling; Liver Function Tests; Male; Monocrotaline; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Muscular Disorders, Atrophic; Myosin Heavy Chains; Protein Isoforms; Rats; Rats, Sprague-Dawley; Sphingolipids; Staurosporine; Tumor Necrosis Factor-alpha | 2002 |
Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
Topics: Adenocarcinoma; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Chromosome Mapping; Colonic Neoplasms; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; Disease Progression; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein Transport; Pyridines; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Up-Regulation | 2002 |
Src activation regulates anoikis in human colon tumor cell lines.
Topics: Adenocarcinoma; Amino Acid Substitution; Anoikis; Apoptosis; bcl-X Protein; Caspase 3; Caspases; Cell Adhesion; Cell Cycle; Chromones; Colonic Neoplasms; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, src; Humans; Morpholines; Mutation, Missense; Neoplasm Metastasis; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins pp60(c-src); Pyridones; Pyrimidines; Recombinant Fusion Proteins; Signal Transduction; Staurosporine; Transfection; Tumor Cells, Cultured | 2002 |
Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enzyme Activation; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mouth Mucosa; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin; Staurosporine; Time Factors | 2004 |
Maspin overexpression modulates tumor cell apoptosis through the regulation of Bcl-2 family proteins.
Topics: Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Line; Cell Line, Tumor; Culture Media, Serum-Free; Cytochromes c; Cytosol; Disease Progression; DNA, Complementary; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Microscopy, Fluorescence; Models, Statistical; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Ribonucleases; Serpins; Staurosporine; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2005 |