staurosporine has been researched along with Colorectal Cancer in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 14 (53.85) | 24.3611 |
| 2020's | 4 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Foulks, JM; Hamblin, S; Hendrickson, TF; Ho, KK; Kanner, SB; Kultgen, SG; Luo, B; McCullar, MV; Parnell, KM; Xu, Y; Yuan, Y | 1 |
| Amin, S; Jaiswal, AS; Law, BK; Narayan, S; Ramisetti, S; Sharma, AK; Singh, P; Singh-Pillay, A | 1 |
| Han, X; Li, HY; Li, J; Liao, J; Peng, B; Shi, R; Wang, FC; Wang, H; Wang, WZ; Xiao, BB; Xu, X; Yang, CR; Yuan, XL | 1 |
| Fan, QZ; He, LJ; Liu, XP; Miao, DD; Zhang, C; Zhang, SP; Zhu, YB | 1 |
| Cheng, M; Li, R; Wang, H; Wang, J | 1 |
| Chen, H; Lai, S; Pang, Q; Wang, Y; Xiao, H | 1 |
| Choung, S; Fong, EJ; Foo, J; Gasho, J; Hashemi, N; Kim, S; Lau, R; Mumenthaler, SM; Spiller, E; Sun, RX; Ung, N | 1 |
| Büküm, N; Danielisová, P; Milan, J; Morell, A; Novotná, E; Wsól, V | 1 |
| Chen, Y; Gu, W; He, S; Qian, Q; Shen, C; Wan, D; Wang, L; Zhao, H; Zhou, H | 1 |
| Gu, W; Gu, Y; He, S; He, Z; Qian, Q; Wan, D; Wang, L; Yi, B | 1 |
| Ashley, N; Bodmer, WF; Jones, M; Ouaret, D; Wilding, J | 1 |
| Jain, A; Jain, R; Jain, S; Kohli, DV | 1 |
| Chen, X; Diao, J; Jing, L; Lin, CC; Liu, Y; Sun, X; Wang, Q; Xu, W | 1 |
| Biffoni, M; Buccarelli, M; Cappellari, M; De Luca, G; Fanciulli, M; Goeman, F; Melucci, E; Pilozzi, E; Ricci-Vitiani, L; Signore, M | 1 |
| Chen, SR; He, XP; Huang, ZJ; Li, JP; Lu, XS; Qin, LS; Shao, Y; Sun, WH; Wang, DD; Zhou, YC | 1 |
| Albasri, A; Benhasouna, A; Chapman, R; Crook, S; Ilyas, M; Jackson, D; Nateri, AS; Seth, R | 1 |
| Kwak, S; Theurkauf, WE; Varmark, H | 1 |
| Crook, S; Elsaba, TM; Ilyas, M; Jackson, D; Martinez-Pomares, L; McCart, A; Robins, AR; Seth, R; Silver, AR; Tomlinson, IP | 1 |
| Ahmed, MA; Ilyas, M; Jackson, D; Jackson, T; Seth, R | 1 |
| Hicks, DJ; Paraskeva, C; Playle, LC; Qualtrough, D | 1 |
| Lai, ZS; Ma, Q; Wang, QY; Zhang, YL; Zhang, ZS | 1 |
| Crittenden, MR; Gough, MJ; Melcher, AA; Sanchez-Perez, L; Vile, RG; Voellmy, R | 1 |
| Desai, AB; Jacobberger, JW; Kinsella, TJ; Loh, T; Sramkoski, RM; Yan, T | 1 |
| Furukawa, K; Kawado, T; Sato, T; Takahashi, M; Takayama, E | 1 |
| Gajkowska, B; Orzechowski, A; Pajak, B | 1 |
| Alvarez, E; Bergman, AM; Eriksson, S; Kroep, JR; Loves, WJ; Peters, GJ; Pinedo, HM; Talianidis, I; van der Wilt, CL; van Groeningen, CJ | 1 |
26 other study(ies) available for staurosporine and Colorectal Cancer
| Article | Year |
|---|---|
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Topics: Aminopyridines; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Discovery; Enzyme Activation; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Protein Serine-Threonine Kinases; Signal Transduction | 2013 |
ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells.
Topics: Adamantane; Antineoplastic Agents; Aza Compounds; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; HCT116 Cells; HT29 Cells; Humans; Molecular Structure; Oxaliplatin; Stem Cells; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
Synthesis and evaluation of chalcone analogues containing a 4-oxoquinazolin-2-yl group as potential anti-tumor agents.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcones; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Mitochondria; Quinazolines; Structure-Activity Relationship | 2019 |
Shape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes.
Topics: Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase 8; Drug Discovery; Drug Screening Assays, Antitumor; G1 Phase; HCT116 Cells; Humans; Molecular Docking Simulation; Phosphorylation; Protein Kinase Inhibitors; S Phase; STAT1 Transcription Factor | 2019 |
PB-10, a thiazolo[4,5-d] pyrimidine derivative, targets p21-activated kinase 4 in human colorectal cancer cells.
Topics: Binding Sites; Cell Adhesion; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Drug Design; G1 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; Molecular Docking Simulation; p21-Activated Kinases; Protein Kinase Inhibitors; Pyrimidines; RNA Interference; RNA, Small Interfering; Thiazoles | 2020 |
The Prediction of Necroptosis-Related lncRNAs in Prognosis and Anticancer Therapy of Colorectal Cancer.
Topics: Cisplatin; Colorectal Neoplasms; CTLA-4 Antigen; Gene Expression Regulation, Neoplastic; Humans; Kaplan-Meier Estimate; Necroptosis; RNA, Long Noncoding; Staurosporine; Tumor Microenvironment | 2022 |
Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response.
Topics: Anthracyclines; Cell Proliferation; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Imaging, Three-Dimensional; Irinotecan; Microscopy, Confocal; Organoids; Staurosporine | 2020 |
Selective inhibition of aldo-keto reductase 1C3: a novel mechanism involved in midostaurin and daunorubicin synergism.
Topics: Aldo-Keto Reductase Family 1 Member C3; Antineoplastic Combined Chemotherapy Protocols; Biotransformation; Colorectal Neoplasms; Daunorubicin; Drug Synergism; Enzyme Inhibitors; fms-Like Tyrosine Kinase 3; HCT116 Cells; Humans; Leukemia, Myeloid, Acute; Staurosporine | 2021 |
VMP1 related autophagy and apoptosis in colorectal cancer cells: VMP1 regulates cell death.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Colorectal Neoplasms; Culture Media, Serum-Free; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Membrane Proteins; Protein Binding; Staurosporine; Up-Regulation | 2014 |
Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: pro-survival role of Ambra1.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Etoposide; Humans; Membrane Proteins; Staurosporine; Up-Regulation | 2014 |
Rapidly derived colorectal cancer cultures recapitulate parental cancer characteristics and enable personalized therapeutic assays.
Topics: Adenocarcinoma; Cell Differentiation; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Enzyme Inhibitors; Goblet Cells; Humans; Keratin-20; Spheroids, Cellular; Staurosporine; Time Factors; Tumor Cells, Cultured | 2014 |
Coated chitosan nanoparticles encapsulating caspase 3 activator for effective treatment of colorectral cancer.
Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Caspase 3; Chitosan; Colorectal Neoplasms; Drug Carriers; Drug Delivery Systems; Enzyme Activation; Formazans; Humans; Nanoparticles; Particle Size; Polymethacrylic Acids; Rabbits; Staurosporine; Tetrazolium Salts | 2015 |
Bax-PGAM5L-Drp1 complex is required for intrinsic apoptosis execution.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Bufanolides; Carrier Proteins; Cell Line, Tumor; Cisplatin; Colorectal Neoplasms; Dynamins; GTP Phosphohydrolases; HCT116 Cells; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Microtubule-Associated Proteins; Mitochondrial Proteins; Multiprotein Complexes; Phosphoprotein Phosphatases; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Staurosporine; Xenograft Model Antitumor Assays | 2015 |
UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; DNA Damage; Drug Synergism; HCT116 Cells; Humans; Irinotecan; Mice; Neoplastic Stem Cells; Protein Kinase Inhibitors; Signal Transduction; Staurosporine; Xenograft Model Antitumor Assays | 2016 |
Pre-clinical characterization of PKC412, a multi-kinase inhibitor, against colorectal cancer cells.
Topics: Animals; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Mice; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Staurosporine; Xenograft Model Antitumor Assays | 2016 |
C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer.
Topics: Cadherins; Cell Line; Cell Movement; Cell Proliferation; Colon; Colorectal Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Microfilament Proteins; Microscopy, Confocal; Oncogenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Tensins; Transfection | 2009 |
A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.
Topics: Animals; Caffeine; Checkpoint Kinase 1; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Breaks, Double-Stranded; DNA Damage; Drosophila; G2 Phase; Gene Knockout Techniques; HCT116 Cells; Humans; Mitosis; Protein Kinases; Protein Serine-Threonine Kinases; Signal Transduction; Staurosporine | 2010 |
The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer.
Topics: AC133 Antigen; Alternative Splicing; Antigens, CD; Apoptosis; Base Sequence; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glycoproteins; Humans; Intestinal Mucosa; Molecular Sequence Data; Neoplastic Stem Cells; Peptides; RNA, Messenger; Staurosporine; Tumor Stem Cell Assay | 2010 |
MLH1 function is context dependent in colorectal cancers.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Proliferation; Colorectal Neoplasms; DNA Mismatch Repair; Gene Knockdown Techniques; Genes, Tumor Suppressor; Humans; MutL Protein Homolog 1; Neoplasm Proteins; Nuclear Proteins; Oncogenes; Staurosporine; Stress, Physiological; Tumor Cells, Cultured | 2011 |
Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines.
Topics: Alkaloids; Antineoplastic Agents; Colorectal Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; G2 Phase; Humans; Radiation-Sensitizing Agents; Staurosporine; Tumor Cells, Cultured; Tumor Stem Cell Assay | 2002 |
Effect of protein kinase C on multidrug resistance of multidrug-resistant colorectal cancer LoVo/Adr cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Colorectal Neoplasms; Doxorubicin; Drug Interactions; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity.
Topics: Animals; Antiviral Agents; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; DNA-Binding Proteins; Flow Cytometry; Ganciclovir; Gene Expression; Gene Expression Regulation; Genetic Therapy; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Phagocytosis; Protein Kinase C; Simplexvirus; Staurosporine; Thymidine Kinase; Transcription Factors | 2004 |
CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
Topics: Antimetabolites, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Base Pair Mismatch; Caffeine; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Checkpoint Kinase 1; Checkpoint Kinase 2; Colorectal Neoplasms; DNA Repair; DNA-Binding Proteins; Humans; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; RNA, Small Interfering; Staurosporine; Thioguanine; Tumor Suppressor Proteins | 2004 |
Effect of staurosporine on N-glycosylation and cell adhesion to fibronectin of SW480 human colorectal adenocarcinoma cells.
Topics: Adenocarcinoma; Cell Adhesion; Cell Line, Tumor; Colorectal Neoplasms; Fibronectins; Gene Expression; Glycosylation; Humans; N-Acetylglucosaminyltransferases; Neoplasm Metastasis; Phosphorylation; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine | 2005 |
Cycloheximide-mediated sensitization to TNF-alpha-induced apoptosis in human colorectal cancer cell line COLO 205; role of FLIP and metabolic inhibitors.
Topics: Apoptosis; Calcimycin; Calcium; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Chelating Agents; Colorectal Neoplasms; Cycloheximide; Dactinomycin; Drug Synergism; Edetic Acid; Egtazic Acid; Enzyme Activation; Enzyme Activators; Humans; Ionophores; Protein Kinase C; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Escape; Tumor Necrosis Factor-alpha | 2005 |
The role of deoxycytidine kinase in gemcitabine cytotoxicity.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Hormonal; Colorectal Neoplasms; Deoxycytidine; Deoxycytidine Kinase; Dexamethasone; Enzyme Inhibitors; Female; Gemcitabine; Gene Expression; Glucocorticoids; HL-60 Cells; Humans; Protein Kinase C; Ribonucleotide Reductases; RNA, Messenger; Staurosporine; Tumor Cells, Cultured; U937 Cells | 2000 |