staurosporine has been researched along with Carcinoma in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (46.15) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Decrion-Barthod, AZ; Launay, S; Mougin, C; Nicolier, M; Prétet, JL | 1 |
| Baba, T; Berchuck, A; Cory Barnett, J; Fujii, S; Kondoh, E; Konishi, I; Matsumura, N; Mori, S; Murphy, SK; Whitaker, RS; Yamaguchi, K | 1 |
| Goncalves, AP; Maximo, V; Soares, P; Videira, A | 1 |
| Bozko, P; Larsen, AK; Raymond, E; Skladanowski, A | 1 |
| Chen, TC; Couldwell, WT; Gopalakrishna, R; Hinton, DR; Law, RE; Simard, M; Su, YZ; Weiss, MH; Zhang, W | 1 |
| Andreeff, M; Chen, JS; Konopleva, M; Mehta, K; Multani, AS; Pathak, S | 1 |
| Bhonde, MR; Daniel, PT; Hanski, C; Hanski, ML; Kohno, K; Magrini, R; Moorthy, D; Müller, A; Sausville, EA; Wiegand, P; Zeitz, M | 1 |
| Daoud, SS; Mixter, P; Redkar, A | 1 |
| Li, X; Lockett, J; Meng, Y; Sheng, S; Yin, S | 1 |
| Comstock, L; Ding, X; Donelli, G; Fasano, A; Fiorentini, C; Goldblum, SE; Guandalini, S; Kaper, JB; Margaretten, K; Uzzau, S | 1 |
| Kaur, G; Sausville, EA; Sebers, S; Seynaeve, CM; Stetler-Stevenson, M; Worland, PJ | 1 |
| Day, ML; Humphrey, PA; Swanson, PE; Wu, S; Zhao, X | 1 |
| Kraiem, Z; Lahat, N; Sobel, E | 1 |
| Blok, LJ; Grossmann, ME; Perry, JE; Tindall, DJ | 1 |
| Djakiew, D; Zolfaghari, A | 1 |
| Hoang, T; Ng, SC; Saeed, B; Zhang, H | 1 |
| Grégoire, M; Harb, J; Meflah, K; Menanteau, J; Segain, JP | 1 |
| Igarashi, Y; Nishiyama, K; Ohi, Y; Ozawa, M; Sakakura, C; Shirahama, T; Sweeney, EA; Takemoto, M | 1 |
| Gschwendt, M; Kittstein, W; Krammer, PH; Möller, P; Sträter, J; von Reyher, U | 1 |
| Heikkilä, P; Kahri, AI; Liu, J; Voutilainen, R | 1 |
| Antinore, MJ; Carrier, F; Fornace, AJ; Harris, CC; Smith, ML; Wang, XW; Zhan, Q | 1 |
| Chang, C; Hu, C; Leu, CM | 1 |
| Abe, S; Furukawa, T; Kitajima, M; Kubota, T; Kumai, K; Otani, Y; Watanabe, M | 1 |
| Beauchemin, N; Fournès, B; Létourneau, S; Sadekova, S; Turbide, C | 1 |
| Shinohara, A; Takahashi, Y; Tamaya, T; Wan, X; Yokoyama, Y | 1 |
| Chinnadurai, G; Lomonosova, E; Theodorakis, P | 1 |
1 review(s) available for staurosporine and Carcinoma
| Article | Year |
|---|---|
Tumor suppressive maspin and epithelial homeostasis.
Topics: Animals; Apoptosis Regulatory Proteins; Carcinoma; Collagen Type XI; Epithelium; Genes, Tumor Suppressor; Homeostasis; Humans; Male; Membrane Glycoproteins; Mice; Prostatic Neoplasms; Serpins; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
25 other study(ies) available for staurosporine and Carcinoma
| Article | Year |
|---|---|
Spatiotemporal activation of caspase-dependent and -independent pathways in staurosporine-induced apoptosis of p53wt and p53mt human cervical carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma; Caspase Inhibitors; Caspases; Enzyme Activation; Female; Humans; Mutation; Signal Transduction; Staurosporine; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms | 2009 |
Targeting slow-proliferating ovarian cancer cells.
Topics: Antineoplastic Agents; Carcinoma; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Disease-Free Survival; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Ovarian Neoplasms; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine | 2010 |
Synergistic growth inhibition of cancer cells harboring the RET/PTC1 oncogene by staurosporine and rotenone involves enhanced cell death.
Topics: Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Carcinoma; Carcinoma, Papillary; Cell Cycle Checkpoints; Cell Death; Cell Division; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Flow Cytometry; Fluorescent Antibody Technique; Humans; Oncogene Proteins, Fusion; Patched Receptors; Proto-Oncogene Proteins c-ret; Receptors, Cell Surface; Rotenone; Staurosporine; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms | 2011 |
Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitors toward human carcinoma cells with different p53 status.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Camptothecin; Carcinoma; Cell Cycle; Colonic Neoplasms; Etoposide; Humans; Staurosporine; Topoisomerase Inhibitors; Tumor Suppressor Protein p53 | 2002 |
Tamoxifen-induced growth arrest and apoptosis in pituitary tumor cells in vitro via a protein kinase C-independent pathway.
Topics: Adenoma; Adult; Animals; Apoptosis; Carcinoma; Cell Division; DNA Fragmentation; Enzyme Inhibitors; Humans; Isoenzymes; Male; Mice; Middle Aged; Neoplasm Proteins; Pituitary Neoplasms; Protein Kinase C; Signal Transduction; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2002 |
Drug-resistant breast carcinoma (MCF-7) cells are paradoxically sensitive to apoptosis.
Topics: Antibiotics, Antineoplastic; Apoptosis; Blotting, Western; Breast Neoplasms; Calcimycin; Carcinoma; Caspase 3; Caspase 8; Caspases; Cell Line, Tumor; Cytochromes c; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Ionophores; Membrane Potentials; Mitochondria; Staurosporine | 2004 |
The broad-range cyclin-dependent kinase inhibitor UCN-01 induces apoptosis in colon carcinoma cells through transcriptional suppression of the Bcl-x(L) protein.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carcinoma; Colonic Neoplasms; Cyclin-Dependent Kinases; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; NF-kappa B; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; STAT3 Transcription Factor; Staurosporine; Trans-Activators; Tumor Cells, Cultured | 2005 |
Implications of p53 in growth arrest and apoptosis on combined treatment of human Mammary epithelial cells with topotecan and UCN-01.
Topics: Antineoplastic Agents; Apoptosis; Breast; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Proliferation; Epithelial Cells; Female; Genes, p53; Humans; Staurosporine; Topotecan; Tumor Cells, Cultured | 2004 |
Zonula occludens toxin modulates tight junctions through protein kinase C-dependent actin reorganization, in vitro.
Topics: Actins; Adenosine Triphosphatases; Alkaloids; Animals; Carcinoma; Cattle; Cell Line; Cholera Toxin; Colonic Neoplasms; Cytoskeleton; Endothelium, Vascular; Endotoxins; Humans; Ileum; Intercellular Junctions; Intestinal Mucosa; Isoenzymes; Kidney Cortex; Male; Organ Specificity; Permeability; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoric Diester Hydrolases; Protein Kinase C; Pulmonary Artery; Rabbits; Rats; Signal Transduction; Species Specificity; Staurosporine; Swine; Tumor Cells, Cultured; Vibrio cholerae | 1995 |
Cell cycle arrest and growth inhibition by the protein kinase antagonist UCN-01 in human breast carcinoma cells.
Topics: Alkaloids; Breast Neoplasms; Carcinoma; Cell Cycle; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Flow Cytometry; Growth Inhibitors; Humans; In Vitro Techniques; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Staurosporine; Time Factors; Tumor Cells, Cultured; Tyrosine | 1993 |
Phorbol ester-induced apoptosis is accompanied by NGFI-A and c-fos activation in androgen-sensitive prostate cancer cells.
Topics: Alkaloids; Androgens; Apoptosis; Carcinoma; DNA Damage; DNA-Binding Proteins; DNA, Neoplasm; Early Growth Response Protein 1; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-fos; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Control of HLA-DR antigen expression by gamma-interferon: separate signal transduction mechanisms in malignant and nonmalignant human thyroid cells.
Topics: Alkaloids; Calcimycin; Carcinoma; Cells, Cultured; Dose-Response Relationship, Drug; Drug Administration Schedule; Goiter; HLA-DR Antigens; Humans; Interferon-gamma; Isoquinolines; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thyroid Neoplasms; Tumor Cells, Cultured | 1993 |
Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation.
Topics: Alkaloids; Amino Acid Sequence; Androgens; Animals; Base Sequence; Binding Sites; Carcinoma; Cell Cycle; Consensus Sequence; DNA; Early Growth Response Transcription Factors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinase C; Rabbits; Rats; Regulatory Sequences, Nucleic Acid; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Staurosporine; Transcription Factors; Zinc Fingers | 1995 |
Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function.
Topics: Alkaloids; Antibodies, Monoclonal; Carbazoles; Carcinogens; Carcinoma; Cell Movement; Dimethyl Sulfoxide; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Indole Alkaloids; Male; Neoplasm Metastasis; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1996 |
Induction of apoptosis in prostatic tumor cell line DU145 by staurosporine, a potent inhibitor of protein kinases.
Topics: Alkaloids; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; bcl-2-Associated X Protein; bcl-X Protein; Caenorhabditis elegans Proteins; Carcinoma; Caspase 2; Caspases; Cell Division; Cell Survival; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Staurosporine; Time Factors; Tumor Cells, Cultured; Up-Regulation | 1996 |
Induction of fibroblast gelatinase B expression by direct contact with cell lines derived from primary tumor but not from metastases.
Topics: Animals; Antibodies, Monoclonal; Carcinoma; Cell Communication; Cells, Cultured; Coculture Techniques; Collagenases; Colonic Neoplasms; Connective Tissue; Connective Tissue Cells; Cytochalasin D; Cytoskeleton; Dexamethasone; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibroblasts; Genistein; Humans; Integrin beta1; Isoflavones; Keratinocytes; Liver Neoplasms; Lung Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Metastasis; Protein Kinase C; Staurosporine; Transcription Factor AP-1; Tumor Cells, Cultured | 1996 |
Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression.
Topics: Androgens; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Male; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Staurosporine | 1997 |
Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.
Topics: Antigens, Neoplasm; Apoptosis; Brefeldin A; Carcinoma; Cell Transformation, Neoplastic; Colonic Neoplasms; Cycloheximide; Cyclopentanes; Dactinomycin; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Humans; Immunologic Capping; Interferon-gamma; Intestinal Mucosa; Membrane Glycoproteins; Nucleic Acid Synthesis Inhibitors; Phorbol Esters; Protein Kinase C; Protein Synthesis Inhibitors; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Adrenomedullin gene expression and its different regulation in human adrenocortical and medullary tumors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenomedullin; Blotting, Northern; Carcinoma; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Gene Expression Regulation; Humans; Peptides; Pheochromocytoma; Protein Kinase C; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate | 1997 |
Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45.
Topics: Antibodies, Monoclonal; Carcinoma; CDC2 Protein Kinase; Cell Cycle Proteins; Colonic Neoplasms; Cyclin B; Cyclin B1; Cyclin E; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epitopes; GADD45 Proteins; Genes, myc; Histones; Humans; Intracellular Signaling Peptides and Proteins; Nuclear Proteins; Nucleosome Assembly Protein 1; Precipitin Tests; Proteins; Recombinant Proteins; RNA, Antisense; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Ultraviolet Rays | 1999 |
Epidermal growth factor (EGF) suppresses staurosporine-induced apoptosis by inducing mcl-1 via the mitogen-activated protein kinase pathway.
Topics: Androstadienes; Apoptosis; Carcinoma; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA, Antisense; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Recombinant Fusion Proteins; Staurosporine; Transfection; Tumor Cells, Cultured; Wortmannin | 2000 |
UCN-01 (7-hydroxystaurosporine) enhances 5-fluorouracil cytotoxicity through down-regulation of thymidylate synthetase messenger RNA.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Enzyme Inhibitors; Fluorouracil; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Staurosporine; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |
The CEACAM1-L Ser503 residue is crucial for inhibition of colon cancer cell tumorigenicity.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Animals; Antigens, CD; Antigens, Differentiation; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoembryonic Antigen; Carcinogenicity Tests; Carcinoma; Cell Adhesion Molecules; Colonic Neoplasms; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Naphthalenes; Point Mutation; Protein Kinase C; Serine; Staurosporine; Tetradecanoylphorbol Acetate; Thionucleotides; Tumor Cells, Cultured | 2001 |
PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cells, Cultured; Clone Cells; Down-Regulation; Endometrial Neoplasms; Female; Mutation; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Staurosporine; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Critical requirement of BAX for manifestation of apoptosis induced by multiple stimuli in human epithelial cancer cells.
Topics: Antibodies; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Carcinoma; Colonic Neoplasms; Epithelial Cells; fas Receptor; Humans; Membrane Glycoproteins; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Thapsigargin; TNF-Related Apoptosis-Inducing Ligand; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |