staurosporine has been researched along with Carcinoma, Squamous Cell in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (50.00) | 18.2507 |
| 2000's | 11 (39.29) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hahlbrock, A; Maushagen, R; Pfannerstill, AC; Pries, R; Rades, D; Rahmanzadeh, R; Reers, S; Stauber, R; Wollenberg, B | 1 |
| Ames-Draycott, A; Benaich, N; Cai, W; Goldie, SJ; Hayes, TF; Sipilä, K; Watt, FM; Yin, G | 1 |
| Clynes, M; Henry, M; Keenan, J; Meleady, P; Murphy, L | 1 |
| Chang, YC; Ho, YC; Lee, SS; Tsai, CH; Yang, SF | 1 |
| Ensley, JF; Gutkind, JS; Igishi, T; Kremer, M; Lahusen, T; Leethanakul, C; Patel, V; Quintanilla-Martinez, L; Sausville, EA; Senderowicz, AM | 1 |
| Hui, ZG; Li, YX; Wu, JX; Yang, WZ; Yu, ZH | 1 |
| Chang, YC; Chou, MY; Hsieh, YS; Tsai, CH; Yang, SF | 1 |
| Amornphimoltham, P; Benavides, F; Conti, CJ; Gutkind, JS; Molinolo, AA; Patel, V; Sauk, J; Sausville, EA; Sriuranpong, V | 1 |
| Li, JR; Ou-Yang, JP; Wang, M; Xia, D; Yu, SB; Zhang, YX | 1 |
| Atarashi, Y; Sato, TA; Stanson, J; Whiteside, TL; Wieckowski, E | 1 |
| Bhawal, UK; Kuniyasu, H; Mitani, Y; Nomura, Y; Otsubo, A; Ozawa, K; Sugiyama, M | 1 |
| Chang, YC; Ho, YC; Lee, SS; Tsai, CH | 1 |
| Akinaga, S; Gomi, K; Nomura, K; Okabe, M | 1 |
| Asaoka, Y; Chang, WC; Liu, YW; Suzuki, H; Yamamoto, S; Yoshimoto, T | 1 |
| Geng, Y; Gross, V; Lotz, M; Villiger, PM; Zhang, B | 1 |
| Hosoi, K; Kurihara, K; Ueha, T | 1 |
| Dlugosz, AA; Hennings, H; Strickland, JE; Yuspa, SH | 1 |
| Ikegami, Y; Nakao, K; Yano, S | 1 |
| Akinaga, S; Akiyama, T; Mizukami, T; Okabe, M; Shimizu, M; Tsujita, T; Yoshida, T | 1 |
| Atsumi, T; Hosoi, K; Kurihara, K; Shioda, Y; Sugita, K; Ueha, T | 1 |
| Abiko, Y; Arai, J; Kaku, T; Mitamura, J | 1 |
| Devoe, G; Gear, R; Heffelfinger, SC; Miller, MA | 1 |
| Alfieri, AA; Sommers, GM | 1 |
| Akinaga, S; Akiyama, T; Okabe, M; Shimizu, M; Tamaoki, T | 1 |
| Hatori, M; Kamijo, R; Nagumo, M; Sumitani, K; Takizawa, K; Toyoshima, T | 1 |
| Bock, JM; Harari, PM; Pickart, MA; Pink, JJ | 1 |
| Akinaga, S; Akiyama, T; Eastman, A; Shimizu, M; Sugiyama, K; Takahashi, R; Tamaoki, T; Yamaguchi, K | 1 |
| Danenberg, KD; Danenberg, PV; Grem, JL; Kao, V; Nguyen, D | 1 |
28 other study(ies) available for staurosporine and Carcinoma, Squamous Cell
| Article | Year |
|---|---|
Effects of paclitaxel on permanent head and neck squamous cell carcinoma cell lines and identification of anti-apoptotic caspase 9b.
Topics: Alternative Splicing; Antineoplastic Agents, Phytogenic; Apoptotic Protease-Activating Factor 1; Carcinoma, Squamous Cell; Caspase 9; Cell Cycle; Cell Death; Cell Line, Tumor; DNA Methylation; Enzyme Activation; Head and Neck Neoplasms; Humans; Membrane Potential, Mitochondrial; Paclitaxel; Promoter Regions, Genetic; Squamous Cell Carcinoma of Head and Neck; Staurosporine | 2016 |
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Carcinoma, Squamous Cell; Caspase 8; Cell Adhesion; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Databases, Genetic; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Genome-Wide Association Study; Genomics; Head and Neck Neoplasms; Humans; Mouth Neoplasms; Mutation; Neoplasm Invasiveness; Phenotype; RNA Interference; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Staurosporine; Transfection | 2016 |
Proteomic analysis of multidrug-resistance mechanisms in adriamycin-resistant variants of DLKP, a squamous lung cancer cell line.
Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Electrophoresis, Gel, Two-Dimensional; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; Prohibitins; Proteomics; Reactive Oxygen Species; Reproducibility of Results; Staurosporine | 2009 |
Hypoxia inducible factor-1α expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Acetylcysteine; Areca; Arecoline; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Squamous Cell; Cell Line; Cholinergic Agonists; Curcumin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Free Radical Scavengers; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Mouth Mucosa; Mouth Neoplasms; Protein Kinase C; Staurosporine; Time Factors; Transcription Factor AP-1 | 2010 |
Antitumor activity of UCN-01 in carcinomas of the head and neck is associated with altered expression of cyclin D3 and p27(KIP1).
Topics: 3T3 Cells; Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cyclin D3; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Head and Neck Neoplasms; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Inhibitory Concentration 50; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Prognosis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; S Phase; Staurosporine; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
[Abrogation of radiation-induced G2 arrest and radiosensitization by 7-hydroxystaurosporine (UCN-01) in human nasopharyngeal carcinoma cell line].
Topics: Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Survival; G2 Phase; Genes, p53; Humans; Mutation; Nasopharyngeal Neoplasms; Protein Kinase C; Radiation-Sensitizing Agents; Staurosporine | 2003 |
Matrix metalloproteinase 2 and matrix metalloproteinase 9 expression in human oral squamous cell carcinoma and the effect of protein kinase C inhibitors: preliminary observations.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Carcinoma, Squamous Cell; Cell Culture Techniques; Down-Regulation; Enzyme Inhibitors; Humans; Keratinocytes; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mouth Mucosa; Mouth Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 2003 |
Persistent activation of the Akt pathway in head and neck squamous cell carcinoma: a potential target for UCN-01.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Disease Progression; Enzyme Activation; Head and Neck Neoplasms; Humans; Immunohistochemistry; Mice; Mouth Mucosa; Neoplasm Transplantation; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin; Staurosporine; Time Factors | 2004 |
Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine.
Topics: Apoptosis; Carcinoma, Squamous Cell; Caspase 3; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Protein Kinase C-alpha; Staurosporine; Survivin; Tongue Neoplasms | 2005 |
FAP-1-mediated activation of NF-kappaB induces resistance of head and neck cancer to Fas-induced apoptosis.
Topics: Antibodies; Apoptosis; Carcinoma, Squamous Cell; CASP8 and FADD-Like Apoptosis Regulating Protein; Cell Line, Tumor; Cell Survival; Cyclohexylamines; Etoposide; fas Receptor; Head and Neck Neoplasms; Humans; NF-kappa B; Protein Phosphatase 1; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Signal Transduction; Staurosporine; Up-Regulation; Vanadates | 2007 |
UCN-01 (7-hydroxystaurosporine) induces apoptosis and G1 arrest of both primary and metastatic oral cancer cell lines in vitro.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Flow Cytometry; G1 Phase; Humans; Mouth Neoplasms; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine | 2007 |
The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas.
Topics: Adult; Aged; Antineoplastic Agents; Areca; Arecoline; Blotting, Western; Carcinoma, Squamous Cell; Curcumin; Epithelium; Female; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Lymphatic Metastasis; Male; Mastication; Middle Aged; Mouth Mucosa; Mouth Neoplasms; Staurosporine; Up-Regulation | 2008 |
Effect of UCN-01, a selective inhibitor of protein kinase C, on the cell-cycle distribution of human epidermoid carcinoma, A431 cells.
Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Cycle; DNA, Neoplasm; Humans; Protein Kinase C; Staining and Labeling; Staurosporine; Time Factors; Tumor Cells, Cultured | 1994 |
Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells.
Topics: Alkaloids; Arachidonate 12-Lipoxygenase; Carcinoma, Squamous Cell; Diglycerides; Enzyme Induction; Epidermal Growth Factor; Humans; Naphthalenes; Phosphatidylinositol Phosphates; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Regulation of interleukin-6 (IL-6) expression: evidence for a tissue-specific role of protein kinase C.
Topics: Alkaloids; Base Sequence; Calcimycin; Carcinoma, Squamous Cell; DNA-Binding Proteins; Gene Expression Regulation; Interleukin-1; Interleukin-6; Laryngeal Neoplasms; Lipopolysaccharides; Molecular Sequence Data; Monocytes; NF-kappa B; Organ Specificity; Polymerase Chain Reaction; Protein Kinase C; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 1993 |
Bradykinin-stimulated transient modulation of epidermal growth factor receptors in A-431 human epidermoid carcinoma cells.
Topics: Alkaloids; Binding, Competitive; Bradykinin; Carcinoma, Squamous Cell; ErbB Receptors; Humans; Marine Toxins; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1993 |
Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Papilloma; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Antitumor effect of CGP41251, a new selective protein kinase C inhibitor, on human non-small cell lung cancer cells.
Topics: Adenocarcinoma; Analysis of Variance; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Cycle; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Transplantation; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1996 |
G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Squamous Cell; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Humans; Microtubule-Associated Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Retinoblastoma Protein; RNA, Messenger; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Proteins | 1997 |
ATP- and EGF-stimulated phosphatidulinositol synthesis by two different pathways, phospholipase D and diacylglycerol kinase, in A-431 epidermoid carcinoma cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Bradykinin; Calcimycin; Calcium; Carcinoma, Squamous Cell; Chelating Agents; Choline; Diacylglycerol Kinase; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Ionophores; Neoplasm Proteins; Pertussis Toxin; Phosphatidic Acids; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phospholipase D; Phosphotransferases (Alcohol Group Acceptor); Pyrimidinones; Receptors, Purinergic P2; Signal Transduction; Staurosporine; Sulfonamides; Thiazoles; Tumor Cells, Cultured; Type C Phospholipases; Virulence Factors, Bordetella | 1996 |
Alteration of proto-oncogenes during apoptosis in the oral squamous cell carcinoma cell line, SAS, induced by staurosporine.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Adhesion; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Fragmentation; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Microscopy, Electron; Mouth Neoplasms; Polymerase Chain Reaction; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; RNA, Messenger; Staurosporine; Transcription, Genetic; Tumor Cells, Cultured | 1997 |
Staurosporine-induced versus spontaneous squamous metaplasia in pre- and postmenopausal breast tissue.
Topics: Adult; Aged; Anticarcinogenic Agents; Breast; Breast Neoplasms; Carcinogens; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Immunophenotyping; Keratin-10; Keratinocytes; Keratins; Middle Aged; Naphthalenes; Postmenopause; Premenopause; Protein Kinase C; Staurosporine; Tamoxifen; Tetradecanoylphorbol Acetate; Thrombomodulin; Tumor Cells, Cultured; Up-Regulation | 1998 |
Multimodality therapy: radiation and continuous concomitant cis-platinum and PKC inhibition in a cervical carcinoma model.
Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Combined Modality Therapy; Enzyme Inhibitors; Female; HeLa Cells; Humans; Protein Kinase C; Radiotherapy Dosage; Spheroids, Cellular; Staurosporine; Tumor Stem Cell Assay; Uterine Cervical Neoplasms | 1998 |
Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole.
Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Squamous Cell; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell-Free System; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mitosis; Nocodazole; Phosphoprotein Phosphatases; Phosphorylation; Proteins; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured; Tyrosine | 1999 |
Nitric oxide up-regulates the expression of intercellular adhesion molecule-1 on cancer cells.
Topics: Benzoates; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Free Radical Scavengers; Genistein; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tongue Neoplasms; Transcription Factor AP-1; Tumor Cells, Cultured; Up-Regulation | 1999 |
Modulation of tumor cell proliferation and apoptosis by polyamine depletion in cells of head and neck squamous cell carcinomas.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Eflornithine; Head and Neck Neoplasms; Humans; Kinetics; Poly(ADP-ribose) Polymerases; Polyamines; Staurosporine; Time Factors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation.
Topics: Alkaloids; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Damage; Drug Synergism; Female; G2 Phase; Genes, p53; Humans; In Situ Nick-End Labeling; Mitomycin; Protein Kinases; S Phase; Staurosporine; Tumor Cells, Cultured | 2000 |
Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.
Topics: Alkaloids; Antimetabolites, Antineoplastic; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Deoxyribonucleotides; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Drug Combinations; Enzyme Inhibitors; Floxuridine; Genes, p53; Humans; Lung Neoplasms; Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |