staurosporine has been researched along with Cancer of Skin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bentke, A; Laidler, P; Małecki, JM; Ostrowska, B | 1 |
| Agarwala, SS; Christensen, SD; Frankel, PH; Gandara, DR; Lara, PN; Li, T; Luu, T; Mack, PC; Margolin, KA | 1 |
| Fox, TE; Gowda, R; Hengst, J; Madhunapantula, SV; Robertson, GP; Yun, JK | 1 |
| Grabacka, M; Plonka, PM; Reiss, K; Urbanska, K | 1 |
| Barth, H; Fürstenberger, G; Gschwendt, M; Kittstein, W; Kleinschroth, J; Leibersperger, H; Lindner, D; Marmé, D; Rudolph, C; Schächtele, C | 1 |
| Dlugosz, AA; Hennings, H; Strickland, JE; Yuspa, SH | 1 |
| Dlugosz, AA; Stanwell, C; Yuspa, SH | 1 |
| Akinaga, S; Akiyama, T; Okabe, M; Shimizu, M; Tamaoki, T | 1 |
| Dong, H; Hirpara, JL; Kini, RM; Loh, KW; Pervaiz, S; Seyed, MA | 1 |
| Arbuck, SG; Bauer, KS; Figg, WD; Fuse, E; Headlee, D; Jaken, S; Jing , X; Kuwabara, T; Lahusen, T; Lush, RM; Messmann, R; Murgo, A; Roberge, M; Sausville, EA; Senderowicz, AM | 1 |
| Dlugosz, AA; Yuspa, SH | 1 |
| Fujiki, H; Matsushima, R; Nakayasu, M; Suganuma, M; Sugimura, T; Suguri, H; Yoshizawa, S | 1 |
| Aizu, E; Hosoda, Y; Kato, R; Kiyoto, I; Nakadate, T; Yamamoto, S | 1 |
| Chida, K; Hirota, K; Kuroki, T; Yamada, S | 1 |
2 trial(s) available for staurosporine and Cancer of Skin
| Article | Year |
|---|---|
A phase II study of cell cycle inhibitor UCN-01 in patients with metastatic melanoma: a California Cancer Consortium trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; California; Cell Cycle; Disease Progression; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Kaplan-Meier Estimate; Male; Melanoma; Middle Aged; Protein Kinase C; Protein Kinase Inhibitors; Skin Neoplasms; Staurosporine; Time Factors; Treatment Outcome | 2012 |
Phase I trial of 72-hour continuous infusion UCN-01 in patients with refractory neoplasms.
Topics: Adult; Aged; Alkaloids; Antineoplastic Agents; DNA Damage; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Neoplasm; Female; Humans; Hyperglycemia; Hypotension; Infusions, Intravenous; Lymphoma, Large B-Cell, Diffuse; Male; Melanoma; Middle Aged; Nausea; Neoplasms; Skin Neoplasms; Staurosporine; Vomiting | 2001 |
12 other study(ies) available for staurosporine and Cancer of Skin
| Article | Year |
|---|---|
Cytochalasin D, LY294002 and olomoucine synergize in promoting death of melanoma cells through activation of caspase-3 and apoptosis.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Chromones; Cytochalasin D; Drug Synergism; Enzyme Activation; Humans; In Situ Nick-End Labeling; Kinetin; Melanoma; Morpholines; Skin Neoplasms; Staurosporine; Up-Regulation | 2010 |
Targeting sphingosine kinase-1 to inhibit melanoma.
Topics: Animals; Apoptosis; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D1; Down-Regulation; Fibroblasts; G1 Phase Cell Cycle Checkpoints; Humans; Lysophospholipids; Melanocytes; Melanoma; Mice; Molecular Targeted Therapy; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Resting Phase, Cell Cycle; RNA, Small Interfering; Skin Neoplasms; Sphingosine; Staurosporine; Thiazoles; Up-Regulation; Xenograft Model Antitumor Assays | 2012 |
Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt.
Topics: Animals; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Fenofibrate; Humans; Hypolipidemic Agents; Melanoma; Mice; Neoplasm Metastasis; Phosphorylation; PPAR alpha; Proto-Oncogene Proteins c-akt; Signal Transduction; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured | 2006 |
Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo.
Topics: 3T3 Cells; Alkaloids; Animals; Anticarcinogenic Agents; Female; Isoenzymes; Mice; Mice, Inbred Strains; Protein Kinase C; Skin; Skin Neoplasms; Staurosporine; Substrate Specificity; Tetradecanoylphorbol Acetate | 1995 |
Inhibition of tumor formation from grafted murine papilloma cells by treatment of grafts with staurosporine, an inducer of squamous differentiation.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Differentiation; Disease Models, Animal; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Papilloma; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured | 1993 |
Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C.
Topics: Alkaloids; Animals; Base Sequence; Biomarkers, Tumor; Cell Differentiation; Cells, Cultured; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Keratinocytes; Mice; Mice, Inbred BALB C; Mice, Inbred SENCAR; Molecular Sequence Data; Neoplasm Proteins; Papilloma; Protein Kinase C; RNA, Messenger; Signal Transduction; Skin Neoplasms; Staurosporine | 1996 |
Differential effects of UCN-01, staurosporine and CGP 41 251 on cell cycle progression and CDC2/cyclin B1 regulation in A431 cells synchronized at M phase by nocodazole.
Topics: Alkaloids; Antineoplastic Agents; Carcinoma, Squamous Cell; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell Cycle Proteins; Cell-Free System; Cyclin B; Cyclin B1; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Mitosis; Nocodazole; Phosphoprotein Phosphatases; Phosphorylation; Proteins; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured; Tyrosine | 1999 |
Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Transport; Caspase Inhibitors; Caspases; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Activation; Enzyme Inhibitors; Etoposide; Fluorescence; HL-60 Cells; Humans; Intracellular Membranes; Melanoma; Mitochondria; Mitochondria, Liver; Neoplasm Proteins; Oligopeptides; Permeability; Photochemistry; Pyrimidinones; Radiation-Sensitizing Agents; Rats; Rats, Wistar; Signal Transduction; Skin Neoplasms; Staurosporine; Tumor Cells, Cultured | 2000 |
Staurosporine induces protein kinase C agonist effects and maturation of normal and neoplastic mouse keratinocytes in vitro.
Topics: Alkaloids; Animals; Carcinogenicity Tests; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Induction; Epidermal Growth Factor; Keratinocytes; Mice; Mice, Inbred BALB C; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; RNA, Messenger; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate; Transglutaminases; Tumor Cells, Cultured | 1991 |
Tumor-promoting activity of staurosporine, a protein kinase inhibitor on mouse skin.
Topics: Alkaloids; Animals; Cell Line; Cell Transformation, Viral; Enzyme Activation; Enzyme Induction; Female; Herpesvirus 4, Human; Histidine Decarboxylase; Humans; Lyngbya Toxins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Protein Kinase Inhibitors; Skin; Skin Neoplasms; Staurosporine | 1990 |
Differential inhibition by staurosporine, a potent protein kinase C inhibitor, of 12-O-tetradecanoylphorbol-13-acetate-caused skin tumor promotion, epidermal ornithine decarboxylase induction, hyperplasia and inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Alkaloids; Animals; Edema; Enzyme Induction; Female; Hyperplasia; Inflammation; Kinetics; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Protein Kinase C; Reference Values; Skin; Skin Neoplasms; Staurosporine; Superoxides; Tetradecanoylphorbol Acetate | 1989 |
Inhibition of phorbol ester-caused induction of ornithine decarboxylase and tumor promotion in mouse skin by staurosporine, a potent inhibitor of protein kinase C.
Topics: Alkaloids; Animals; Cocarcinogenesis; Enzyme Induction; Hyperplasia; Mice; Ornithine Decarboxylase; Protein Kinase C; Skin Neoplasms; Staurosporine; Tetradecanoylphorbol Acetate | 1988 |