staurosporine has been researched along with Cancer of Prostate in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (31.58) | 18.2507 |
| 2000's | 18 (47.37) | 29.6817 |
| 2010's | 7 (18.42) | 24.3611 |
| 2020's | 1 (2.63) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, Y; Guo, H; Li, K; Li, Y; Liu, D; Ma, T; Wen, J; Zhao, L; Zhou, D | 1 |
| Chen, C; Chen, G; Chen, QH; Sarabia, C; Wang, G; Wang, R; Zhang, Q; Zhang, X; Zheng, S | 1 |
| Addo, EM; Anaya-Eugenio, GD; Carcache de Blanco, EJ; Ezzone, N; Henkin, JM; Kinghorn, AD; Ninh, TN; Ren, Y; Soejarto, DD | 1 |
| Arafa, RK; Castanet, AS; Nafie, MS; Said, SA | 1 |
| Huh, YJ; Park, JW; Yang, ES | 1 |
| Hiemstra, S; Khanal, G; Pappas, D | 1 |
| Deeg, M; Echner, H; Ernemann, U; Heckl, S; Horger, M; Nägele, T; Schwentner, C; Sheikh, S; Sturzu, A; Weidenmaier, C | 1 |
| Gao, L; Pan, TJ; Peng, YY; Yang, JR | 1 |
| Shimizu, T; Tachibana, K; Takeda, K; Tonami, K | 1 |
| Do, TN; Douglas, GP; Drew, L; Fine, RL; Petrylak, DP | 1 |
| Garcia, FU; Hu, Y; Stearns, ME; Wang, M | 1 |
| Alley, MC; Dasmahapatra, GP; Didolkar, P; Ghosh, S; Roy, KK; Sausville, EA | 1 |
| Ferbeyre, G; Mukhopadhyay, UK; Senderowicz, AM | 1 |
| Daida, H; Kashiwakura, Y; Kumon, H; Kusumi, N; Nagai, A; Nasu, Y; Sasano, T; Shimada, T; Tamayose, K; Watanabe, M | 1 |
| Inoue, T; Okayama, A; Shimizu, T; Takeda, K | 1 |
| Li, X; Lockett, J; Meng, Y; Sheng, S; Yin, S | 1 |
| Brown, E; Gronda, M; Gurfinkel, D; Hurren, R; Konopleva, M; Mawji, IA; Pellecchia, M; Pond, GR; Reed, JC; Schimmer, AD; Thomas, MP | 1 |
| Barnes, JM; Cohen, MB; Henry, MD; Rokhlin, OW; Svensson, RU | 1 |
| Blok, LJ; Gong, Y; Lindzey, JK; Perry, JE; Tindall, DJ | 1 |
| Day, ML; Humphrey, PA; Swanson, PE; Wu, S; Zhao, X | 1 |
| Cohen, MB; Rokhlin, OW | 1 |
| Blok, LJ; Grossmann, ME; Perry, JE; Tindall, DJ | 1 |
| Djakiew, D; Zolfaghari, A | 1 |
| Hoang, T; Ng, SC; Saeed, B; Zhang, H | 1 |
| Igarashi, Y; Nishiyama, K; Ohi, Y; Ozawa, M; Sakakura, C; Shirahama, T; Sweeney, EA; Takemoto, M | 1 |
| Lavelle, F | 1 |
| Cohen, MB; Glover, RA; Rokhlin, OW | 1 |
| Cunningham, GR; Denner, L; He, Z; Kagan, C; Mannucci, R; Marcelli, M; Nicoletti, I; Sturgis, L; Teng, B; Walkup, M | 1 |
| Ben-Josef, E; Joshi, B; Li, L; Porter, AT; Taffe, BG; Tang, DG; Taylor, JD; Tian, H; Wahl, S; Zhu, Z | 1 |
| Denner, L; Haidacher, SJ; Li, X; Mannucci, R; Marani, M; Marcelli, M; Nicoletti, I; Sturgis, L; Trial, JA | 1 |
| Shimizu, T; Takahashi, N; Takeda, K | 1 |
| Andriani, F; Denner, L; Kinsey, B; Li, X; Mannucci, R; Marani, M; Marcelli, M; Nicoletti, I | 1 |
| Blagosklonny, MV; Dixon, SC; Figg, WD; Robey, R | 1 |
| Day, ML; Zhao, X | 1 |
| Cheville, JC; Huang, H; Pan, Y; Roche, PC; Schmidt, LJ; Tindall, DJ | 1 |
| Basu, A; Brown, AM; Haldar, S; Kuryshev, YA; Wang, L; Wible, BA | 1 |
| Fischer, K; Hescheler, J; Sauer, H; Wartenberg, M | 1 |
| Andrews, PE; Montgomery, BT; Tindall, DJ; Young, CY | 1 |
1 review(s) available for staurosporine and Cancer of Prostate
| Article | Year |
|---|---|
Tumor suppressive maspin and epithelial homeostasis.
Topics: Animals; Apoptosis Regulatory Proteins; Carcinoma; Collagen Type XI; Epithelium; Genes, Tumor Suppressor; Homeostasis; Humans; Male; Membrane Glycoproteins; Mice; Prostatic Neoplasms; Serpins; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
37 other study(ies) available for staurosporine and Cancer of Prostate
| Article | Year |
|---|---|
Synthesis and biological evaluation of quinoline derivatives as potential anti-prostate cancer agents and Pim-1 kinase inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Molecular Structure; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Quinolines; Structure-Activity Relationship | 2016 |
Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Hydrocarbons, Aromatic; Male; Prostate; Prostatic Neoplasms; Structure-Activity Relationship; Trientine | 2017 |
Caspase-Dependent Apoptosis in Prostate Cancer Cells and Zebrafish by Corchorusoside C from Streptocaulon juventas.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apocynaceae; Apoptosis; Caspases; Cell Line, Tumor; Humans; I-kappa B Kinase; Male; Molecular Structure; Poly (ADP-Ribose) Polymerase-1; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrans; Vietnam; Zebrafish | 2019 |
Discovery of PIM-1 kinase inhibitors based on the 2,5-disubstituted 1,3,4-oxadiazole scaffold against prostate cancer: Design, synthesis, in vitro and in vivo cytotoxicity investigation.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Male; Mice; Oxadiazoles; Prostatic Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-pim-1; Staurosporine; Structure-Activity Relationship | 2023 |
RNA interference targeting sensitive-to-apoptosis gene potentiates doxorubicin- and staurosporine-induced apoptosis of PC3 cells.
Topics: Acetylcysteine; Apoptosis; Cell Line, Tumor; Doxorubicin; Humans; Male; Prostatic Neoplasms; Reactive Oxygen Species; RNA Interference; RNA, Small Interfering; Staurosporine; Ubiquitin-Protein Ligases | 2013 |
Probing hypoxia-induced staurosporine resistance in prostate cancer cells with a microfluidic culture system.
Topics: Antineoplastic Agents; Apoptosis; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Equipment Design; Humans; Hypoxia; Male; Microfluidic Analytical Techniques; Prostate; Prostatic Neoplasms; Staurosporine | 2014 |
Chemosensitization of Prostate Carcinoma Cells with a Receptor-directed Smac Conjugate.
Topics: Adjuvants, Pharmaceutic; Aldehydes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drug Screening Assays, Antitumor; Fluorescent Dyes; Humans; Male; Oligopeptides; Prostatic Neoplasms; Receptors, Odorant; Rhodamines; Staurosporine; Ultraviolet Rays | 2016 |
[Effects of staurosporine on the proliferation and apoptosis of prostate cancer PC-3 cells].
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Humans; Male; Prostatic Neoplasms; Staurosporine | 2011 |
Staurosporine enhances the expression of tissue inhibitor of metalloproteinase-1 in human prostate cancer cells.
Topics: Base Sequence; DNA Primers; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Recombinant Proteins; RNA, Messenger; Staurosporine; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured | 2002 |
The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.
Topics: Androgens; Antineoplastic Agents; Apoptosis; bcl-X Protein; Blotting, Western; Caspases; Cell Division; Cytochrome c Group; Depsipeptides; Enzyme Activation; Enzyme Inhibitors; Humans; JNK Mitogen-Activated Protein Kinases; Lactams; Lactones; Male; Microtubules; Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines.
Topics: Antibodies; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Interleukin-10; Leupeptins; Male; Phosphorylation; Phosphotyrosine; Prostatic Neoplasms; Protease Inhibitors; Proto-Oncogene Proteins c-rel; Signal Transduction; Staurosporine; Tissue Inhibitor of Metalloproteinase-1 | 2003 |
In vitro combination treatment with perifosine and UCN-01 demonstrates synergism against prostate (PC-3) and lung (A549) epithelial adenocarcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Cycle; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Humans; Immunoblotting; Lung Neoplasms; Male; Phosphorylcholine; Prostatic Neoplasms; Signal Transduction; Staurosporine; Time Factors | 2004 |
RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells.
Topics: Antibiotics, Antineoplastic; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Cycle Proteins; Diploidy; DNA Damage; DNA-Binding Proteins; Doxorubicin; Fibroblasts; G2 Phase; Gene Expression; Gene Silencing; Genes, cdc; Genes, p53; Humans; Male; Mutation; Proliferating Cell Nuclear Antigen; Prostatic Neoplasms; Protein Serine-Threonine Kinases; RNA Interference; RNA, Catalytic; RNA, Neoplasm; RNA, Small Interfering; Staurosporine; Transfection; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 2005 |
Adeno-associated virus 2-mediated intratumoral prostate cancer gene therapy: long-term maspin expression efficiently suppresses tumor growth.
Topics: Animals; Apoptosis; Cell Proliferation; Dependovirus; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Genetic Therapy; Genetic Vectors; Humans; Injections, Intralesional; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Prostate; Prostatic Neoplasms; Serpins; Staurosporine; Survival Rate; Transduction, Genetic; Tumor Cells, Cultured | 2005 |
Analysis of gene expression during staurosporine-induced neuronal differentiation of human prostate cancer cells.
Topics: Blotting, Northern; Cell Differentiation; Cell Line, Tumor; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Oligonucleotide Array Sequence Analysis; Prostatic Neoplasms; RNA, Messenger; Staurosporine | 2005 |
Identification of small molecules that sensitize resistant tumor cells to tumor necrosis factor-family death receptors.
Topics: Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; fas Receptor; Humans; Ligands; Male; Membrane Glycoproteins; Prostatic Neoplasms; Receptors, Tumor Necrosis Factor; Staurosporine; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha | 2006 |
Chemotherapeutic agents up-regulate the cytomegalovirus promoter: implications for bioluminescence imaging of tumor response to therapy.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line; Cytomegalovirus; Doxorubicin; Humans; Luminescence; Male; Mice; Neoplasms; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Biosynthesis; Staurosporine; Up-Regulation | 2007 |
Calcium regulation of androgen receptor expression in the human prostate cancer cell line LNCaP.
Topics: Alkaloids; Apoptosis; Blotting, Northern; Blotting, Western; Calcimycin; Calcium; Calcium-Transporting ATPases; Cell Line; Cell Nucleus; Dactinomycin; Dose-Response Relationship, Drug; Gene Expression; Humans; Kinetics; Male; Prostatic Neoplasms; Protein Kinase C; Receptors, Androgen; RNA, Messenger; RNA, Neoplasm; Staurosporine; Terpenes; Thapsigargin; Tumor Cells, Cultured | 1995 |
Phorbol ester-induced apoptosis is accompanied by NGFI-A and c-fos activation in androgen-sensitive prostate cancer cells.
Topics: Alkaloids; Androgens; Apoptosis; Carcinoma; DNA Damage; DNA-Binding Proteins; DNA, Neoplasm; Early Growth Response Protein 1; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Protein Kinases; Proto-Oncogene Proteins c-fos; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 1994 |
Differential sensitivity of human prostatic cancer cell lines to the effects of protein kinase and phosphatase inhibitors.
Topics: Alkaloids; Antigens, CD; Antigens, Neoplasm; Cell Adhesion Molecules; Cell Division; Endoglin; Enzyme Inhibitors; Ethers, Cyclic; Genistein; Humans; Hyaluronan Receptors; Intercellular Adhesion Molecule-1; Isoflavones; Male; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Prostatic Neoplasms; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Cell Surface; Staurosporine; Tumor Cells, Cultured; Vanadates; Vascular Cell Adhesion Molecule-1 | 1995 |
Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation.
Topics: Alkaloids; Amino Acid Sequence; Androgens; Animals; Base Sequence; Binding Sites; Carcinoma; Cell Cycle; Consensus Sequence; DNA; Early Growth Response Transcription Factors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Kruppel-Like Transcription Factors; Male; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinase C; Rabbits; Rats; Regulatory Sequences, Nucleic Acid; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Staurosporine; Transcription Factors; Zinc Fingers | 1995 |
Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function.
Topics: Alkaloids; Antibodies, Monoclonal; Carbazoles; Carcinogens; Carcinoma; Cell Movement; Dimethyl Sulfoxide; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Immunoblotting; Indole Alkaloids; Male; Neoplasm Metastasis; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1996 |
Induction of apoptosis in prostatic tumor cell line DU145 by staurosporine, a potent inhibitor of protein kinases.
Topics: Alkaloids; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; bcl-2-Associated X Protein; bcl-X Protein; Caenorhabditis elegans Proteins; Carcinoma; Caspase 2; Caspases; Cell Division; Cell Survival; DNA, Neoplasm; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Male; Molecular Sequence Data; Oligonucleotides; Polymerase Chain Reaction; Prostatic Neoplasms; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Staurosporine; Time Factors; Tumor Cells, Cultured; Up-Regulation | 1996 |
Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression.
Topics: Androgens; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinoma; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Lysophospholipids; Male; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Sphingosine; Staurosporine | 1997 |
[Tyrosine protein kinase inhibitors in cancerology: the end of the beginning?].
Topics: Animals; ErbB Receptors; Humans; In Vitro Techniques; Male; Mice; Neoplasms; Prostatic Neoplasms; Protein-Tyrosine Kinases; Quinazolines; Rats; Staurosporine; Structure-Activity Relationship | 1997 |
Fas-mediated apoptosis in human prostatic carcinoma cell lines occurs via activation of caspase-8 and caspase-7.
Topics: Apoptosis; Blotting, Western; Caspase 7; Caspase 8; Caspase 9; Caspases; Enzyme Activation; fas Receptor; Humans; Male; Prostatic Neoplasms; Retinoblastoma Protein; Staurosporine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer.
Topics: Apoptosis; Butyrates; Caspase 2; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Cytochrome c Group; Enzyme Activation; Genetic Therapy; Humans; Male; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured | 1999 |
Apoptosis induction by a novel anti-prostate cancer compound, BMD188 (a fatty acid-containing hydroxamic acid), requires the mitochondrial respiratory chain.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Electron Transport; Humans; Hydroxamic Acids; Male; Membrane Potentials; Mitochondria; Piperidones; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Reactive Oxygen Species; Staurosporine; Tumor Cells, Cultured | 1999 |
Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Biological Transport; Caspase 3; Caspase 7; Caspases; Catalysis; Cell Survival; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Humans; In Situ Nick-End Labeling; Intracellular Membranes; Male; Mitochondria; Necrosis; Poly(ADP-ribose) Polymerases; Prostatic Neoplasms; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2000 |
Low-dose staurosporine suppresses proliferation and induces neurites in human prostatic cancer TSU-Pr1 cells.
Topics: Acetylcholinesterase; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Growth Inhibitors; Humans; Kinetics; Male; Neurites; Prostatic Neoplasms; Staurosporine; tau Proteins; Tumor Cells, Cultured | 2000 |
Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells.
Topics: Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; bcl-X Protein; Carrier Proteins; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Genistein; Humans; Male; Mitochondria; Prostatic Neoplasms; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Staurosporine; Subcellular Fractions; Tumor Cells, Cultured | 2001 |
Resistance to growth inhibitory and apoptotic effects of phorbol ester and UCN-01 in aggressive cancer cell lines.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA, Neoplasm; Down-Regulation; Drug Resistance, Neoplasm; Formazans; Humans; Immunoblotting; Male; Prostatic Neoplasms; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tetrazolium Salts; Transfection; Tumor Cells, Cultured | 2001 |
RB activation and repression of C-MYC transcription precede apoptosis of human prostate epithelial cells.
Topics: Apoptosis; Blotting, Northern; Blotting, Western; Cell Division; Cell Line; Enzyme Activation; Epithelial Cells; Genes, myc; Genes, Retinoblastoma; Humans; Male; Phosphorylation; Prostate; Prostatic Neoplasms; Protein Kinase C; Proto-Oncogene Proteins c-myc; Staurosporine; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured | 2001 |
PTEN induces chemosensitivity in PTEN-mutated prostate cancer cells by suppression of Bcl-2 expression.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Cell Separation; Cyclic AMP Response Element-Binding Protein; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoblotting; Immunohistochemistry; Male; Microscopy, Confocal; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Binding; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; RNA, Messenger; Signal Transduction; Staurosporine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Proteins; Up-Regulation; Vincristine | 2001 |
Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells.
Topics: Adenoviridae; Animals; Apoptosis; Flow Cytometry; Humans; Jurkat Cells; Male; Mice; Mice, Nude; Molecular Chaperones; Phosphorylation; Potassium; Prostatic Neoplasms; Protein Inhibitors of Activated STAT; Staurosporine; Transplantation, Heterologous; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cyclins; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Male; Mimosine; Mitomycin; Prostatic Neoplasms; Purines; Roscovitine; Staurosporine; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Tumor-promoting phorbol ester down-regulates the androgen induction of prostate-specific antigen in a human prostatic adenocarcinoma cell line.
Topics: Alkaloids; Antigens, Neoplasm; Biomarkers, Tumor; Calcimycin; Colforsin; Dose-Response Relationship, Drug; Down-Regulation; Humans; Male; Nandrolone; Phorbols; Prostate-Specific Antigen; Prostatic Neoplasms; RNA, Messenger; Staurosporine; Testosterone Congeners; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1992 |