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staurosporine and Cancer of Ovary

staurosporine has been researched along with Cancer of Ovary in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (25.00)18.2507
2000's10 (50.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmad, I; Chhikara, BS; Kumar, A; Mandal, D; Parang, K; Tiwari, R1
Csuk, R; Siewert, B1
Hu, S; Jin, Y; Li, S; Ma, W; Ren, D; Wu, N; Xiao, S1
Alsamman, K; El-Masry, OS1
Li, X; Liao, QP1
Baba, T; Berchuck, A; Cory Barnett, J; Fujii, S; Kondoh, E; Konishi, I; Matsumura, N; Mori, S; Murphy, SK; Whitaker, RS; Yamaguchi, K1
Auersperg, N; Choi, KC; Leung, PC; Tai, CJ; Tzeng, CR1
De Geyter, C; De Geyter, M; Dürrenberger, M; Vollmer, M; Zhang, H1
Brown, S; Chen, EX; Dancey, JE; Hirte, HW; Hotte, SJ; Moore, M; Oza, A; Pond, GR; Winquist, EW1
Altevogt, P; Gast, D; Gutwein, P; Issa, Y; Sanderson, MP; Stoeck, A1
Chung, WH; Han, K; Han, KT; Kim, M; Kim, Y; Lim, J; Park, IY1
Brown, S; Carey, MS; Dancey, JE; Hirte, HW; Hotte, SJ; Oza, AM; Pond, GR; Tsao, MS; Welch, S1
Gregory-Bass, RC; Liu, D; Matthews, R; Olatinwo, M; Stiles, JK; Thomas, K; Thompson, WE; Tsang, B; Xu, W1
Chorvath, B; Duraj, J; Hunakova, L; Novotny, L; Sedlak, J1
Chorváth, B; Novotný, L; Sedlák, J1
Collins, JL; Manning, K; Powell, CB1
Aghajanian, C; Husain, A; Rosales, N; Schwartz, GK; Spriggs, DR; Yan, XJ1
Idei, T; Igarashi, N; Kikuchi, A; Matukawa, T; Nakayama, Y; Ohtani, K; Sakamoto, H; Satoh, K1
Novotny, L; Rauko, P; Szekeres, T; Yalowitz, JA1
Andrews, PA; Howell, SB; Isonishi, S1

Reviews

1 review(s) available for staurosporine and Cancer of Ovary

ArticleYear
Antitumor activity of benzamide riboside in vitro and in vivo.
    Current medicinal chemistry, 2002, Volume: 9, Issue:7

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; DNA Replication; Female; Humans; IMP Dehydrogenase; In Vitro Techniques; Leukemia L1210; Nucleosides; Ovarian Neoplasms; Staurosporine; Survival Rate

2002

Trials

2 trial(s) available for staurosporine and Cancer of Ovary

ArticleYear
Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Infusions, Intravenous; Leukopenia; Male; Middle Aged; Neutropenia; Ovarian Neoplasms; Salivary Gland Neoplasms; Staurosporine; Survival Analysis; Topotecan

2006
UCN-01 in combination with topotecan in patients with advanced recurrent ovarian cancer: a study of the Princess Margaret Hospital Phase II consortium.
    Gynecologic oncology, 2007, Volume: 106, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Staurosporine; Topotecan

2007

Other Studies

17 other study(ies) available for staurosporine and Cancer of Ovary

ArticleYear
Synthesis of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates and evaluation of their Src kinase inhibitory and anticancer activities.
    Bioorganic & medicinal chemistry letters, 2011, Mar-01, Volume: 21, Issue:5

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Ovarian Neoplasms; Pyrans; Pyrimidines; src-Family Kinases; Triazoles

2011
Membrane damaging activity of a maslinic acid analog.
    European journal of medicinal chemistry, 2014, Mar-03, Volume: 74

    Topics: Cell Line, Tumor; Cell Membrane; Female; Humans; Molecular Structure; Ovarian Neoplasms; Triterpenes

2014
RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation.
    BMC cancer, 2018, 01-10, Volume: 18, Issue:1

    Topics: Apoptosis; Biomarkers, Pharmacological; Chromosomal Proteins, Non-Histone; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Lung Neoplasms; Ovarian Neoplasms; rac1 GTP-Binding Protein; Staurosporine

2018
Staurosporine alleviates cisplatin chemoresistance in human cancer cell models by suppressing the induction of SQSTM1/p62.
    Oncology reports, 2018, Volume: 40, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Autophagy; Biomarkers, Tumor; Breast Neoplasms; Cell Proliferation; Cisplatin; Colonic Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Sequestosome-1 Protein; Staurosporine; Tumor Cells, Cultured

2018
[Expression of connexin 43 in ovarian cancer and its relationship with chemoresistance].
    Zhonghua fu chan ke za zhi, 2009, Volume: 44, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Connexin 43; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Gap Junctions; Humans; Immunohistochemistry; Middle Aged; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase C; Staurosporine; Transfection

2009
Targeting slow-proliferating ovarian cancer cells.
    International journal of cancer, 2010, May-15, Volume: 126, Issue:10

    Topics: Antineoplastic Agents; Carcinoma; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytostatic Agents; Disease-Free Survival; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Ki-67 Antigen; Ovarian Neoplasms; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine

2010
Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells.
    Biology of reproduction, 2003, Volume: 68, Issue:1

    Topics: Adenosine Triphosphate; Cell Division; DNA-Binding Proteins; Epithelium; ets-Domain Protein Elk-1; Female; Flavonoids; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; Precancerous Conditions; Proto-Oncogene Proteins; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; RNA, Messenger; RNA, Neoplasm; Staurosporine; Transcription Factors; Tumor Cells, Cultured

2003
Apoptosis and differentiation induced by staurosporine in granulosa tumor cells is coupled with activation of JNK and suppression of p38 MAPK.
    International journal of oncology, 2005, Volume: 26, Issue:6

    Topics: Apoptosis; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Female; Granulosa Cell Tumor; Humans; JNK Mitogen-Activated Protein Kinases; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Progesterone; Prostaglandin-Endoperoxide Synthases; Signal Transduction; Staurosporine

2005
L1-CAM in a membrane-bound or soluble form augments protection from apoptosis in ovarian carcinoma cells.
    Gynecologic oncology, 2007, Volume: 104, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Cell Line, Tumor; CHO Cells; Cisplatin; Cricetinae; Cricetulus; Female; Humans; Neural Cell Adhesion Molecule L1; Ovarian Neoplasms; Sphingosine; Staurosporine; Transfection

2007
Antitumor and normal cell protective effect of PKC412 in the athymic mouse model of ovarian cancer.
    Annals of clinical and laboratory science, 2006,Autumn, Volume: 36, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Body Weight; Cell Line, Tumor; Cytokines; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Protein Kinase C; Spleen; Staurosporine; Xenograft Model Antitumor Assays

2006
Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis.
    International journal of cancer, 2008, May-01, Volume: 122, Issue:9

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Endometrioid; Carcinoma, Papillary; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; G1 Phase; Gene Expression Regulation, Neoplastic; Gene Silencing; Genetic Vectors; Humans; Ki-67 Antigen; Microscopy, Fluorescence; Mitochondria; Ovarian Neoplasms; Ovary; Prohibitins; Recombinant Proteins; Repressor Proteins; Resting Phase, Cell Cycle; RNA, Small Interfering; Staurosporine; Up-Regulation

2008
Effects of protein kinase C inhibitor, staurosporine derivative CGP 41 251, on cell cycle, DNA synthesis and drug uptake in neoplastic cell lines.
    Anti-cancer drugs, 1995, Volume: 6, Issue:1

    Topics: Alkaloids; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Cycle; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Resistance, Multiple; Drug Synergism; Female; Humans; Leukemia L1210; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mice; Mice, Inbred DBA; Neoplasm Proteins; Ovarian Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1995
The protein kinase C inhibitor, CGP 41 251, reverses decreased daunomycin uptake in a human drug-resistant ovarian carcinoma cell line.
    International journal of cancer, 1994, Dec-15, Volume: 59, Issue:6

    Topics: Alkaloids; Daunorubicin; Drug Resistance; Female; Flow Cytometry; Humans; Ovarian Neoplasms; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1994
Interferon-alpha (IFN alpha) induces a cytolytic mechanism in ovarian carcinoma cells through a protein kinase C-dependent pathway.
    Gynecologic oncology, 1993, Volume: 50, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Analysis of Variance; Cell Survival; Dactinomycin; Dose-Response Relationship, Drug; Emetine; Female; Humans; Interferon alpha-2; Interferon-alpha; Isoquinolines; Ovarian Neoplasms; Piperazines; Protein Biosynthesis; Protein Kinase C; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
UCN-01 in ovary cancer cells: effective as a single agent and in combination with cis-diamminedichloroplatinum(II)independent of p53 status.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:11

    Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Survival; Cisplatin; Drug Synergism; Female; Genes, p53; Humans; Mutagenesis; Ovarian Neoplasms; Recombinant Proteins; Staurosporine; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1997
Follicle-stimulating hormone promotes the growth of human epithelial ovarian cancer cells through the protein kinase C-mediated system.
    Cancer letters, 2001, May-26, Volume: 166, Issue:2

    Topics: Cell Division; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Female; Follicle Stimulating Hormone; Humans; Isoenzymes; Ovarian Neoplasms; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Thymidine

2001
Increased sensitivity to cis-diamminedichloroplatinum(II) in human ovarian carcinoma cells in response to treatment with 12-O-tetradecanoylphorbol 13-acetate.
    The Journal of biological chemistry, 1990, Mar-05, Volume: 265, Issue:7

    Topics: Alkaloids; Cell Line; Cell Survival; Cisplatin; Female; Humans; Kinetics; Ovarian Neoplasms; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1990