staurosporine has been researched along with Brain Neoplasms in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (42.42) | 18.2507 |
| 2000's | 12 (36.36) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, LC; Chen, CH; Chen, Y; Choi, J; Hilliard, TS; Kawakami, JK; Li, Y; Miklossy, G; Paladino, D; Sarkaria, JN; Sun, D; Turkson, J; Wongwiwatthananukit, S; Youn, UJ; Yue, P; Zhang, M | 1 |
| Hsu, HC; Li, L; Shcherbakova, DM; Verkhusha, VV; Wang, LV | 1 |
| Tseng, CL; Wei, JW | 1 |
| Biffoni, M; De Majo, M; De Maria, R; di Martino, S; Giannetti, S; Larocca, LM; Morgante, L; Pallini, R; Pelacchi, F; Petricoin, EF; Ricci-Vitiani, L; Runci, D; Signore, M; Stancato, L | 1 |
| Felbor, U; Fischer, A; Schleider, E; Stahl, S; Walter, U; Wüstehube, J | 1 |
| Chen, WJ; Chou, AK; Chou, CH; Hong, YR; Howng, SL; Hsu, CM; Lin, CC; Loh, JK; Lung, FW; Wei, CC; Yang, MC | 1 |
| Blaber, M; Blaber, SI; Decker, PA; Drucker, KL; Giannini, C; Jenkins, RB; O'Neill, BP; Paulsen, AR; Scarisbrick, IA; Uhm, JH | 1 |
| Bates, TE; Daley, E; Davies, D; Dewey, RA; Kos, J; Lah, TT; Levicar, N; Pilkington, GJ | 1 |
| Chen, TC; Fry, D; Liebes, L; Su, S | 1 |
| Arita, K; Hama, S; Heike, Y; Kajiwara, Y; Kurisu, K; Sugiyama, K; Yahara, K; Yamasaki, F; Yoshioka, H | 1 |
| Shaikh, SA; Shirsat, NV | 1 |
| Chen, GG; Leung, BC; Ng, HK; Poon, WS; Sin, FL | 2 |
| Dawson, G; Goswami, R; Kilkus, J; Phillips, G; Singh, D | 1 |
| Arita, K; Hama, S; Hidaka, T; Kajiwara, Y; Kurisu, K; Murakami, T; Saito, T; Sugiyama, K; Yamasaki, F; Yoshioka, H | 1 |
| Barna, BP; Barnett, GH; Estes, ML; Gupta, MK; Iwasaki, K; Toms, SA | 1 |
| Couldwell, WT; Hinton, DR; Law, RE; Weiss, MH | 1 |
| Baltuch, GH; Couldwell, WT; Villemure, JG; Yong, VW | 1 |
| Maruyama, K; Nishimura, E; Sasaki, K; Tsukada, T; Yamaguchi, K | 1 |
| Arbuckle, J; Boddeke, HW; Boeijinga, P; Docherty, RJ; Meigel, I | 1 |
| Kawecki, S; Lazo, JS; Pollack, IF | 1 |
| Akerman, KE; Courtney, MJ; Kukkonen, JP; Shariatmadari, R | 1 |
| Manzini, S; Palma, C | 1 |
| Bernhard, EJ; Janss, AJ; Levow, C; McKenna, WG; Muschel, RJ; Phillips, PC; Sutton, L | 1 |
| Chakravarthy, BR; Hill, IE; MacManus, JP; Rasquinha, I; Walker, T | 1 |
| Bredel, M; Freund, JM; Lazo, JS; Pollack, IF; Rusnak, J | 1 |
| Henderson, J; Kim, TW; Kovacs, DM; Mancini, R; Na, SJ; Schmidt, SD; Tanzi, RE | 1 |
| Asai, A; Kirino, T; Kuchino, Y; Narita, Y | 1 |
| Ceccatelli, S; Gorman, AM; Hirt, UA; Orrenius, S | 1 |
| Costa, S; Fages, C; Monville, C; Paillaud, E; Plassat, JL; Rochette-Egly, C; Tardy, M | 1 |
| Chambers, WH; Erff, ML; Okada, H; Pollack, IF; Witham, TF | 1 |
| Lee, CM; Tung, WL; Young, JD | 1 |
| Antel, JP; Couldwell, WT; Uhm, JH; Yong, VW | 1 |
33 other study(ies) available for staurosporine and Brain Neoplasms
| Article | Year |
|---|---|
Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma.
Topics: alpha Karyopherins; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Female; Glioma; Glucosephosphate Dehydrogenase; HSP110 Heat-Shock Proteins; Humans; Magnetic Resonance Spectroscopy; Mice, Nude; Microtubule-Associated Proteins; Molecular Docking Simulation; Molecular Structure; STAT3 Transcription Factor; Structure-Activity Relationship; Thioredoxin Reductase 1; Trans-Activators; Vimentin; Xenograft Model Antitumor Assays | 2015 |
Multiscale Photoacoustic Tomography of a Genetically Encoded Near-Infrared FRET Biosensor.
Topics: Animals; Apoptosis; Brain Neoplasms; Caspase 3; Ear Neoplasms; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; HeLa Cells; Humans; Luminescent Proteins; Mice; Photoacoustic Techniques; Staurosporine; Tomography, X-Ray Computed | 2021 |
Homologous desensitization of histamine-mediated signal transduction system in C6 glioma cells.
Topics: Animals; Arachidonic Acid; Brain Neoplasms; Calcium; Cell Line, Tumor; Glioma; Histamine; Inositol Phosphates; Pyrilamine; Rats; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate | 2013 |
Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Glioblastoma; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Neoplastic Stem Cells; Protein Array Analysis; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proteomics; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Signal Transduction; Small Molecule Libraries; Staurosporine; Temozolomide; Time Factors; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Evidence for anti-angiogenic and pro-survival functions of the cerebral cavernous malformation protein 3.
Topics: Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Endothelial Cells; Hemangioma, Cavernous, Central Nervous System; Humans; Membrane Proteins; Mutation; Neovascularization, Physiologic; Proto-Oncogene Proteins; Recombinant Proteins; Staurosporine; Transfection | 2011 |
GSK3β regulates Bcl2L12 and Bcl2L12A anti-apoptosis signaling in glioblastoma and is inhibited by LiCl.
Topics: Apoptosis; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; HEK293 Cells; Humans; Lithium Chloride; Muscle Proteins; Phosphorylation; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Staurosporine; tau Proteins; Two-Hybrid System Techniques | 2012 |
Clinical significance and novel mechanism of action of kallikrein 6 in glioblastoma.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Proliferation; Cisplatin; Enzyme Inhibitors; Glioblastoma; Humans; Kallikreins; Neoplasm Grading; Prognosis; Real-Time Polymerase Chain Reaction; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Survival Rate; Tumor Cells, Cultured | 2013 |
Selective suppression of cathepsin L by antisense cDNA impairs human brain tumor cell invasion in vitro and promotes apoptosis.
Topics: Apoptosis; Brain Neoplasms; Caspase 3; Caspases; Cathepsin L; Cathepsins; Cell Adhesion; Cell Division; Cell Movement; Cysteine Endopeptidases; DNA, Antisense; DNA, Complementary; Genetic Therapy; Glioblastoma; Humans; Neoplasm Invasiveness; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tumor Cells, Cultured | 2003 |
Combination therapy with irinotecan and protein kinase C inhibitors in malignant glioma.
Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Camptothecin; Cell Line; Glioblastoma; Humans; Irinotecan; Naphthalenes; Perylene; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Staurosporine; Tamoxifen; Tumor Cells, Cultured | 2003 |
Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line.
Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Brain Neoplasms; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; G1 Phase; G2 Phase; Gene Expression Regulation, Neoplastic; Genetic Vectors; Glioma; Humans; Retinoblastoma Protein; Staurosporine; Transfection; Tumor Cells, Cultured | 2003 |
Overexpression of the immediate early gene fra-1 inhibits proliferation, induces apoptosis, and reduces tumourigenicity of c6 glioma cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Apoptosis; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Differentiation; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Clone Cells; Enzyme Inhibitors; Feedback, Physiological; Gene Expression Regulation, Neoplastic; Glioma; Proto-Oncogene Proteins c-fos; Rats; Staurosporine; Transcription Factor AP-1 | 2003 |
Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death.
Topics: Annexin A5; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Brain Neoplasms; Cell Line, Tumor; DNA-Activated Protein Kinase; DNA-Binding Proteins; Drug Resistance, Neoplasm; Enzyme Inhibitors; fas Receptor; Glioblastoma; Humans; In Situ Nick-End Labeling; Indicators and Reagents; Membrane Proteins; Nuclear Proteins; Propidium; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Staurosporine | 2005 |
Differential role of hydrogen peroxide and staurosporine in induction of cell death in glioblastoma cells lacking DNA-dependent protein kinase.
Topics: Apoptosis; Brain Neoplasms; Cell Death; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Inhibitors; Glioblastoma; Humans; Hydrogen Peroxide; Necrosis; Nuclear Proteins; Oxidants; Protein Serine-Threonine Kinases; Staurosporine | 2005 |
Ceramide regulation of the tumor suppressor phosphatase PTEN in rafts isolated from neurotumor cell lines.
Topics: Androstadienes; Animals; Apoptosis; Brain Neoplasms; Caspase 3; Caspase 8; Caspases; Cell Division; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Humans; Membrane Microdomains; Oligodendroglioma; PC12 Cells; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Protein Kinase Inhibitors; PTEN Phosphohydrolase; Rats; Sphingosine; Staurosporine; Transfection; Tumor Suppressor Proteins; Wortmannin | 2005 |
Retinoblastoma protein prevents staurosporine-induced cell death in a retinoblastoma-defective human glioma cell line.
Topics: Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; Genes, p16; Glioma; Humans; Retinoblastoma Protein; Staurosporine; Transfection | 2007 |
Inhibitory effects of tamoxifen and tumor necrosis factor alpha on human glioblastoma cells.
Topics: Alkaloids; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Division; Drug Synergism; Glioma; Humans; Receptors, Estrogen; Receptors, Progesterone; Receptors, Tumor Necrosis Factor; Staurosporine; Tamoxifen; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1995 |
Paradoxical elevation of Ki-67 labeling with protein kinase inhibition in malignant gliomas.
Topics: Alkaloids; Brain Neoplasms; Cell Cycle; Flow Cytometry; Glioma; Humans; Immunohistochemistry; Ki-67 Antigen; Neoplasm Proteins; Nuclear Proteins; Protein Kinase C; Staurosporine; Tamoxifen; Tumor Cells, Cultured | 1995 |
Protein kinase C inhibitors suppress cell growth in established and low-passage glioma cell lines. A comparison between staurosporine and tamoxifen.
Topics: Alkaloids; Brain Neoplasms; Cell Count; Cell Division; Cell Line; Dose-Response Relationship, Drug; Glioblastoma; Glioma; Humans; Protein Kinase C; Staurosporine; Tamoxifen; Tumor Cells, Cultured | 1993 |
Decrease in neuron-restrictive silencer factor (NRSF) mRNA levels during differentiation of cultured neuroblastoma cells.
Topics: Actins; Brain Neoplasms; Carcinogens; Cell Differentiation; Colforsin; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Pheochromocytoma; Polymerase Chain Reaction; Repressor Proteins; RNA, Messenger; Staurosporine; Transcription Factors; Tumor Cells, Cultured | 1996 |
Modulation by calcineurin of 5-HT3 receptor function in NG108-15 neuroblastoma x glioma cells.
Topics: 1-Methyl-3-isobutylxanthine; Amino Acid Sequence; Animals; Brain Neoplasms; Calcineurin; Calmodulin-Binding Proteins; Chelating Agents; Egtazic Acid; Enzyme Inhibitors; Glioma; Half-Life; Molecular Sequence Data; Neuroblastoma; Okadaic Acid; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Rats; Receptors, Serotonin; Staurosporine; Tumor Cells, Cultured | 1996 |
Blocking of glioma proliferation in vitro and in vivo and potentiating the effects of BCNU and cisplatin: UCN-01, a selective protein kinase C inhibitor.
Topics: Alkaloids; Brain Neoplasms; Carmustine; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glioma; Humans; Protein Kinase C; Staurosporine; Tumor Cells, Cultured | 1996 |
Localization of voltage-sensitive Ca2+ fluxes and neuropeptide Y immunoreactivity to varicosities in SH-SY5Y human neuroblastoma cells differentiated by treatment with the protein kinase inhibitor staurosporine.
Topics: Brain Neoplasms; Calcium Channel Blockers; Calcium Channels; Cell Differentiation; Culture Media; Electrophysiology; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Humans; Immunohistochemistry; Ion Channel Gating; Neuroblastoma; Neuropeptide Y; Protein Kinase Inhibitors; Staurosporine | 1997 |
Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells.
Topics: Astrocytoma; Brain Neoplasms; Cytokines; Dipeptides; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Indoles; Interleukin-6; Interleukin-8; Leukemia Inhibitory Factor; Lymphokines; Neoplasm Proteins; Neurokinin-1 Receptor Antagonists; Protein Kinase C; Receptors, Neurokinin-1; RNA, Messenger; RNA, Neoplasm; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1998 |
Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines.
Topics: Apoptosis; Brain Neoplasms; Caffeine; Camptothecin; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; G2 Phase; Humans; Staurosporine; Tumor Cells, Cultured | 1998 |
Activation of DNA-dependent protein kinase may play a role in apoptosis of human neuroblastoma cells.
Topics: Apoptosis; Brain Neoplasms; Caspases; DNA Fragmentation; DNA-Activated Protein Kinase; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrazones; Immunoblotting; Neuroblastoma; Nuclear Proteins; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Pyridones; Staurosporine; Tumor Cells, Cultured; Ultraviolet Rays | 1999 |
Protein kinase C inhibition by UCN-01 induces apoptosis in human glioma cells in a time-dependent fashion.
Topics: Alkaloids; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Coloring Agents; Electrophoresis, Agar Gel; Enzyme Inhibitors; Glioma; Humans; In Situ Nick-End Labeling; Protein Kinase C; Staurosporine; Time Factors; Trypan Blue; Tumor Cells, Cultured | 1999 |
Staurosporine-induced activation of caspase-3 is potentiated by presenilin 1 familial Alzheimer's disease mutations in human neuroglioma cells.
Topics: Alzheimer Disease; Amino Acid Substitution; Apoptosis; Brain Neoplasms; Caspase 3; Caspases; Enzyme Activation; Enzyme Precursors; Glioma; Humans; Membrane Proteins; Point Mutation; Poly(ADP-ribose) Polymerases; Presenilin-1; Recombinant Fusion Proteins; Staurosporine; Transfection | 1999 |
Actinomycin D and staurosporine, potent apoptosis inducers in vitro, are potentially effective chemotherapeutic agents against glioblastoma multiforme.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cisplatin; Dactinomycin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Glioblastoma; Humans; Nimustine; Staurosporine; Tumor Cells, Cultured | 2000 |
Dexamethasone pre-treatment interferes with apoptotic death in glioma cells.
Topics: Animals; Antineoplastic Agents, Hormonal; Apoptosis; Astrocytoma; Brain Neoplasms; Dexamethasone; Enzyme Inhibitors; Humans; Metabolism; Rats; Staurosporine; Tumor Cells, Cultured | 2000 |
Retinoic acid increases proliferation rate of GL-15 glioma cells, involving activation of STAT-3 transcription factor.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Carcinogens; Cell Division; Cell Nucleus; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioma; Humans; Protein Transport; Receptors, Retinoic Acid; RNA, Messenger; STAT3 Transcription Factor; Staurosporine; Tetradecanoylphorbol Acetate; Trans-Activators; Tretinoin; Tumor Cells, Cultured | 2002 |
7-Hydroxystaurosporine-induced apoptosis in 9L glioma cells provides an effective antigen source for dendritic cells and yields a potent vaccine strategy in an intracranial glioma model.
Topics: Alkaloids; Animals; Antigens, Neoplasm; Apoptosis; Brain Neoplasms; Cancer Vaccines; Cell Communication; Dendritic Cells; Drug Administration Schedule; Enzyme Inhibitors; Glioma; Gliosarcoma; Rats; Staurosporine; Tumor Cells, Cultured; Vaccination | 2002 |
Tachykinin-stimulated inositol phospholipid hydrolysis and taurine release from human astrocytoma cells.
Topics: Alkaloids; Astrocytoma; Brain Neoplasms; Down-Regulation; Humans; Hydrolysis; Phosphatidylinositols; Protein Kinase C; Receptors, Neurotransmitter; Receptors, Tachykinin; Staurosporine; Substance P; Tachykinins; Taurine; Tetradecanoylphorbol Acetate; Tritium; Tumor Cells, Cultured | 1992 |
Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro.
Topics: Alkaloids; Animals; Brain Neoplasms; Cell Division; DNA, Neoplasm; Glioma; Humans; Protein Kinase C; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1991 |