staurosporine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aguilera-Montilla, N; Amigo-Jiménez, I; Bailón, E; García-Marco, JA; García-Pardo, A; Terol, MJ | 1 |
| Dunleavy, K; Figg, WD; Grant, ND; Jaffe, ES; Janik, JE; Marti, GE; Steinberg, SM; Stetler-Stevenson, M; Tohnya, T; White, T; Wilson, WH | 1 |
| Cheson, BD | 1 |
| Keating, MJ; Plunkett, W; Yamauchi, T | 1 |
| Anichini, A; Baldassarri, P; Bersani, I; Carlo-Stella, C; Di Nicola, M; Gianni, AM; Magni, M; Matteucci, P; Mortarini, R; Napoli, S; Romagnoli, L | 1 |
| Baou, M; Naresh, K; Wagner, SD; Willimott, S | 1 |
| Jamieson, GP; Snook, MB; Thurlow, PJ; Wiley, JS | 1 |
| Byrd, JC; Grever, MR; Rai, KR; Sausville, EA | 1 |
| Byrd, JC; Flinn, IW; Grever, MR; Lehman, T; Lucas, D; Sausville, E; Shinn, C; Willis, CR | 1 |
| Champain, K; Csermak, K; Ganeshaguru, K; Gordon, M; Hart, SM; Hoffbrand, AV; Jones, DT; Man, A; Mehta, AB; Prentice, HG; Virchis, AE; Wickremasinghe, RG | 1 |
2 review(s) available for staurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Hematologic malignancies: new developments and future treatments.
Topics: Adenine Nucleotides; Alemtuzumab; Alkaloids; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Cell Cycle; Cell Survival; Clofarabine; Cytosine; Dioxolanes; Flavonoids; Hematologic Neoplasms; Humans; Immunoconjugates; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Non-Hodgkin; Multiple Myeloma; NF-kappa B; Nitrogen Mustard Compounds; Oligonucleotides, Antisense; Peptide Hydrolases; Piperidines; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Remission Induction; Rituximab; Staurosporine; Thionucleotides | 2002 |
Old and new therapies in chronic lymphocytic leukemia: now is the time for a reassessment of therapeutic goals.
Topics: Alkaloids; Antineoplastic Agents, Alkylating; Bryostatins; Flavonoids; Humans; Lactones; Leukemia, Lymphocytic, Chronic, B-Cell; Macrolides; Piperidines; Staurosporine; Topoisomerase I Inhibitors | 1998 |
1 trial(s) available for staurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Phase I trial of 7-hydroxystaurosporine and fludararbine phosphate: in vivo evidence of 7-hydroxystaurosporine induced apoptosis in chronic lymphocytic leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Apoptosis; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytosis; Male; Middle Aged; Staurosporine; Treatment Outcome; Vidarabine Phosphate | 2011 |
7 other study(ies) available for staurosporine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Communication; Cell Line; Class I Phosphatidylinositol 3-Kinases; Coculture Techniques; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Mesenchymal Stem Cells; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Oxides; Phosphorylation; Protein Kinase C beta; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Purines; Quinazolinones; RNA Interference; Signal Transduction; STAT3 Transcription Factor; Staurosporine; Time Factors; Transfection; Tumor Cells, Cultured; Tumor Microenvironment; Up-Regulation | 2015 |
UCN-01 (7-hydroxystaurosporine) inhibits DNA repair and increases cytotoxicity in normal lymphocytes and chronic lymphocytic leukemia lymphocytes.
Topics: Alkaloids; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Cells, Cultured; Cyclophosphamide; DNA Damage; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Combinations; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Staurosporine; Ultraviolet Rays | 2002 |
Dendritic cell viability is decreased after phagocytosis of apoptotic tumor cells induced by staurosporine or vaccinia virus infection.
Topics: Antigen Presentation; Antigens, Neoplasm; Apoptosis; B-Lymphocytes; Cancer Vaccines; Coculture Techniques; Culture Media, Conditioned; Dendritic Cells; Humans; Interferon-gamma; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Monocytes; Phagocytosis; Staurosporine; T-Lymphocytes; Tumor Cells, Cultured; Ultraviolet Rays; Vaccination; Vaccinia virus | 2003 |
CD154 induces a switch in pro-survival Bcl-2 family members in chronic lymphocytic leukaemia.
Topics: Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; CD40 Ligand; Cell Proliferation; Cell Survival; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Interleukin-4; Leukemia, Lymphocytic, Chronic, B-Cell; Lymph Nodes; Mice; Minor Histocompatibility Antigens; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; Staurosporine; Tumor Cells, Cultured; Vidarabine | 2007 |
Extracellular ATP causes of loss of L-selectin from human lymphocytes via occupancy of P2Z purinocepters.
Topics: Adenosine Triphosphate; Alkaloids; Calcium; Cells, Cultured; Down-Regulation; Humans; L-Selectin; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Magnesium; Protein Kinase C; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
UCN-01 induces cytotoxicity toward human CLL cells through a p53-independent mechanism.
Topics: Alkaloids; Animals; Antineoplastic Agents; Apoptosis; Cell Survival; Cells, Cultured; Chlorambucil; Drug Resistance, Multiple; Genes, bcl-2; Humans; Interleukin-4; Kinetics; Leukemia, Lymphocytic, Chronic, B-Cell; Mice; Mice, Inbred C57BL; Mice, Knockout; Prednisone; Proto-Oncogene Proteins c-bcl-2; Spleen; Staurosporine; Thymus Gland; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vidarabine | 2001 |
Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.
Topics: 2-Chloroadenosine; Aged; Aged, 80 and over; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; B-Lymphocytes; Calcium Channel Blockers; Chlorambucil; Deoxyadenosines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; In Situ Nick-End Labeling; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Palatine Tonsil; Protein Kinase C; Staurosporine; Tumor Cells, Cultured; Verapamil; Vidarabine | 2002 |