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staurosporine aglycone and Retinoblastoma

staurosporine aglycone has been researched along with Retinoblastoma in 1 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wagner, N1
Wagner, KD1
Sefton, M1
Rodríguez-Tébar, A1
Grantyn, R1

Other Studies

1 other study available for staurosporine aglycone and Retinoblastoma

ArticleYear
An abnormal response of retinoblastoma cells (Y-79) to neurotrophins.
    Investigative ophthalmology & visual science, 2000, Volume: 41, Issue:7

    Topics: Carbazoles; Cell Differentiation; Cell Division; DNA Primers; DNA, Neoplasm; Down-Regulation; Enzyme

2000