staurosporine aglycone has been researched along with Polyploid in 11 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we have extended these studies to the staurosporine analogs K252a, lestaurtinib, PKC412, stauprimide, and UCN-01 and analyzed their influence on process extension, cell cycle distribution, and induction of polyploidy in four SCLC cell lines." | 7.81 | Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells. ( Courts, C; Gallala, H; Janzen, V; Kraus, D; Nowak, M; Perner, S; Probstmeier, R; Veit, N; Winter, J, 2015) |
| "Mouse 2nH1 (ES) cells were examined for polyploidization using K-252a and staurosporine." | 7.74 | Polyploidization of 2nH1 (ES) cells by K-252a and staurosporine. ( Fujikawa-Yamamoto, K; Miyagoshi, M; Yamagishi, H, 2007) |
| "To examine whether or not cells polyploidized by different mechanisms behave in a different manner after drug removal, V79 Chinese hamster cells were assessed by flow cytometry (FCM) after their polyploidization by demecolcine and K-252a, inhibitors of spindle-fiber formation and protein kinase, respectively." | 7.70 | Different responses of polyploidized V79 cells after removal of two drugs, demecolcine and K-252a. ( Fujikawa-Yamamoto, K; Ohdoi, C; Wang, SY; Yamagishi, H; Zong, ZP, 2000) |
| " Here, we have extended these studies to the staurosporine analogs K252a, lestaurtinib, PKC412, stauprimide, and UCN-01 and analyzed their influence on process extension, cell cycle distribution, and induction of polyploidy in four SCLC cell lines." | 3.81 | Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells. ( Courts, C; Gallala, H; Janzen, V; Kraus, D; Nowak, M; Perner, S; Probstmeier, R; Veit, N; Winter, J, 2015) |
| "Mouse 2nH1 (ES) cells were examined for polyploidization using K-252a and staurosporine." | 3.74 | Polyploidization of 2nH1 (ES) cells by K-252a and staurosporine. ( Fujikawa-Yamamoto, K; Miyagoshi, M; Yamagishi, H, 2007) |
| "To examine whether or not cells polyploidized by different mechanisms behave in a different manner after drug removal, V79 Chinese hamster cells were assessed by flow cytometry (FCM) after their polyploidization by demecolcine and K-252a, inhibitors of spindle-fiber formation and protein kinase, respectively." | 3.70 | Different responses of polyploidized V79 cells after removal of two drugs, demecolcine and K-252a. ( Fujikawa-Yamamoto, K; Ohdoi, C; Wang, SY; Yamagishi, H; Zong, ZP, 2000) |
| "However, the biological significance of polyploid cells and the relation between polyploidy and prognosis is not well understood." | 1.30 | Apoptotic cell death of high polyploid cells in a cultured sarcoma cell line. ( Fujikawa-Yamamoto, K; Li, AL; Murakami, M; Odashima, S; Ota, T; Tanino, M; Yamaguchi, N; Zong, ZP, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (54.55) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gallala, H | 1 |
| Winter, J | 1 |
| Veit, N | 1 |
| Nowak, M | 1 |
| Perner, S | 1 |
| Courts, C | 1 |
| Kraus, D | 1 |
| Janzen, V | 1 |
| Probstmeier, R | 1 |
| Fujikawa-Yamamoto, K | 6 |
| Yamagishi, H | 4 |
| Miyagoshi, M | 2 |
| Zong, ZP | 3 |
| Teraoka, K | 1 |
| Tanino, M | 3 |
| Odashima, S | 3 |
| Yokoe, H | 1 |
| Masumi-Fukazawa, A | 1 |
| Sunohara, M | 1 |
| Tanzawa, H | 1 |
| Sato, K | 1 |
| Sato, T | 1 |
| Fuse, A | 1 |
| Kobayashi, S | 2 |
| Teramura, M | 2 |
| Ito, K | 1 |
| Iwabe, K | 2 |
| Inaba, T | 1 |
| Mizoguchi, H | 2 |
| Yoshinaga, K | 1 |
| Hoshikawa, Y | 1 |
| Maeda, T | 1 |
| Hatakeyama, M | 1 |
| Quentmeier, H | 1 |
| Zaborski, M | 1 |
| Drexler, HG | 1 |
| Ota, T | 1 |
| Murakami, M | 2 |
| Li, AL | 1 |
| Yamaguchi, N | 2 |
| Zong, Z | 1 |
| Li, A | 1 |
| Chang, YG | 1 |
| Ohdoi, C | 1 |
| Wang, SY | 1 |
11 other studies available for staurosporine aglycone and Polyploid
| Article | Year |
|---|---|
Staurosporine analogs promote distinct patterns of process outgrowth and polyploidy in small cell lung carcinoma cells.
Topics: Carbazoles; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Furans; Humans; Indole Alkaloids; Poly | 2015 |
Establishment of a triploid V79 cell line from tetraploid cells obtained through polyploidization using K-252a.
Topics: Animals; Carbazoles; Cell Cycle; Cell Division; Cell Line; Cell Size; Chromosomes; Cricetinae; Diplo | 2002 |
Polyploidization of 2nH1 (ES) cells by K-252a and staurosporine.
Topics: Alkaline Phosphatase; Animals; Carbazoles; Cell Cycle; Cells, Cultured; Culture Media; DNA; Embryona | 2007 |
Potentiation of K252a, a protein kinase inhibitor-induced polyploidization by cAMP in cultured fibrosarcoma cell line.
Topics: Adenosine Triphosphate; Animals; Bucladesine; Carbazoles; Cyclic AMP-Dependent Protein Kinases; Cycl | 1994 |
Induction of polyploidization in the human erythroleukemia cell line (HEL) by protein kinase inhibitor (K252a) and the phorbol-ester TPA.
Topics: Antigens, CD34; Carbazoles; Carcinogens; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle; Cell C | 1997 |
Transcription factor NF-E2 is essential for the polyploidization of a human megakaryoblastic cell line, Meg-J.
Topics: Basic Helix-Loop-Helix Transcription Factors; Carbazoles; DNA-Binding Proteins; Electrophoresis, Pol | 1998 |
K-252a-induced polyploidization and differentiation of a human megakaryocytic cell line, Meg-J: transient elevation and subsequent suppression of cyclin B1 and cdc2 expression in the process of polyploidization.
Topics: Carbazoles; CDC2 Protein Kinase; Cell Differentiation; Cyclin B; Enzyme Inhibitors; Humans; Indole A | 1998 |
Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e.
Topics: Carbazoles; Cell Cycle Proteins; Cell Division; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cy | 1998 |
Apoptotic cell death of high polyploid cells in a cultured sarcoma cell line.
Topics: Animals; Apoptosis; Carbazoles; Cell Division; Cell Survival; DNA, Neoplasm; Enzyme Inhibitors; Flow | 1998 |
Cell membrane changes of structure and function in protein kinase inhibitor-induced polyploid cells.
Topics: Animals; Bucladesine; Carbazoles; Cell Adhesion; Cell Division; Cell Line; Cell Membrane; Cyclic AMP | 2000 |
Different responses of polyploidized V79 cells after removal of two drugs, demecolcine and K-252a.
Topics: Animals; Carbazoles; Cell Count; Cell Cycle; CHO Cells; Cricetinae; Demecolcine; DNA; Enzyme Inhibit | 2000 |