staurosporine aglycone has been researched along with Parkinson Disease in 2 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Real, CC | 1 |
| Ferreira, AF | 1 |
| Chaves-Kirsten, GP | 1 |
| Torrão, AS | 1 |
| Pires, RS | 1 |
| Britto, LR | 1 |
| Wang, LH | 1 |
| Besirli, CG | 1 |
| Johnson, EM | 1 |
1 review available for staurosporine aglycone and Parkinson Disease
| Article | Year |
|---|---|
Mixed-lineage kinases: a target for the prevention of neurodegeneration.
Topics: Alzheimer Disease; Animals; Carbazoles; Hearing Loss; Humans; Indole Alkaloids; Indoles; JNK Mitogen | 2004 |
1 other study available for staurosporine aglycone and Parkinson Disease
| Article | Year |
|---|---|
BDNF receptor blockade hinders the beneficial effects of exercise in a rat model of Parkinson's disease.
Topics: Analysis of Variance; Animals; Apomorphine; Carbazoles; Corpus Striatum; Disease Models, Animal; Enz | 2013 |