staurosporine aglycone has been researched along with Pain in 5 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Von Frey filament testing of somatic referral regions was evaluated as a method to measure referred pain in a rat model of acute necrotizing pancreatitis induced by L-arginine." | 3.72 | Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a. ( He, ZJ; Micci, MA; Pasricha, PJ; Shenoy, M; Toma, H; Winston, JH; Xiao, SY; Zou, L, 2003) |
| "Heat hyperalgesia induced by peripheral injection of CFA was significantly reversed by roscovitine, TrkB-IgG, and the TrkB inhibitor K252a, respectively." | 1.40 | The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats. ( Huang, JL; Lu, H; Shao, HJ; Wang, WY; Xue, QS; Yu, BW; Zhang, HH; Zhang, S; Zhang, XQ, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, HH | 1 |
| Zhang, XQ | 1 |
| Xue, QS | 1 |
| Huang, JL | 1 |
| Zhang, S | 1 |
| Shao, HJ | 1 |
| Lu, H | 1 |
| Wang, WY | 1 |
| Yu, BW | 1 |
| Tao, W | 1 |
| Chen, Q | 1 |
| Wang, L | 1 |
| Zhou, W | 1 |
| Wang, Y | 1 |
| Zhang, Z | 1 |
| Li, YQ | 1 |
| Li, H | 1 |
| Wei, J | 1 |
| Qu, L | 1 |
| Wu, LA | 1 |
| Winston, JH | 1 |
| Toma, H | 1 |
| Shenoy, M | 1 |
| He, ZJ | 1 |
| Zou, L | 1 |
| Xiao, SY | 1 |
| Micci, MA | 1 |
| Pasricha, PJ | 1 |
| Obata, K | 1 |
| Yamanaka, H | 1 |
| Dai, Y | 1 |
| Mizushima, T | 1 |
| Fukuoka, T | 1 |
| Tokunaga, A | 1 |
| Noguchi, K | 1 |
5 other studies available for staurosporine aglycone and Pain
| Article | Year |
|---|---|
The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cyclin-Dependent Kinase 5; Freund's Adjuvant | 2014 |
Brainstem brain-derived neurotrophic factor signaling is required for histone deacetylase inhibitor-induced pain relief.
Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; gamma-Aminobutyric Acid; Glutama | 2015 |
Expression changes of K+-Cl- co-transporter 2 and Na+-K+-Cl- co-transporter1 in mouse trigeminal subnucleus caudalis following pulpal inflammation.
Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Dental Pulp; Dental Pulp Disease | 2010 |
Acute pancreatitis results in referred mechanical hypersensitivity and neuropeptide up-regulation that can be suppressed by the protein kinase inhibitor k252a.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Carbazoles; Cyclic AMP-Dependent Protein Kinases | 2003 |
Activation of extracellular signal-regulated protein kinase in the dorsal root ganglion following inflammation near the nerve cell body.
Topics: Animals; Behavior, Animal; Blotting, Western; Brain-Derived Neurotrophic Factor; Butadienes; Carbazo | 2004 |