Page last updated: 2024-10-29

staurosporine aglycone and Neuralgia

staurosporine aglycone has been researched along with Neuralgia in 3 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.

Research Excerpts

ExcerptRelevanceReference
"Many drugs approved for neuropathic pain engage spinal noradrenergic and cholinergic systems for analgesia."1.37A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury. ( Eisenach, JC; Hayashida, K, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayashida, K1
Eisenach, JC1
Sung, B1
Lim, G1
Mao, J1
Miletic, G1
Hanson, EN1
Miletic, V1

Other Studies

3 other studies available for staurosporine aglycone and Neuralgia

ArticleYear
A tropomyosine receptor kinase inhibitor blocks spinal neuroplasticity essential for the anti-hypersensitivity effects of gabapentin and clonidine in rats with peripheral nerve injury.
    The journal of pain, 2011, Volume: 12, Issue:1

    Topics: Acetylcholine; Amines; Analgesics; Animals; Carbazoles; Choline O-Acetyltransferase; Clonidine; Cycl

2011
Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Apr-01, Volume: 23, Issue:7

    Topics: Amino Acid Transport System X-AG; Animals; Behavior, Animal; Biological Transport; Carbazoles; Const

2003
Brain-derived neurotrophic factor-elicited or sciatic ligation-associated phosphorylation of cyclic AMP response element binding protein in the rat spinal dorsal horn is reduced by block of tyrosine kinase receptors.
    Neuroscience letters, 2004, May-06, Volume: 361, Issue:1-3

    Topics: Afferent Pathways; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Chronic Disease; Cyclic A

2004