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staurosporine aglycone and Nerve Degeneration

staurosporine aglycone has been researched along with Nerve Degeneration in 5 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"Curcumin is a major active component isolated from Curcuma longa."1.35Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB. ( Li, XJ; Li, YB; Li, YH; Wang, R; Wu, HL; Xu, Y, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, SY1
Wang, TF1
Yu, L1
Jen, CJ1
Chuang, JI1
Wu, FS1
Wu, CW1
Kuo, YM1
Wang, R1
Li, YB1
Li, YH1
Xu, Y1
Wu, HL1
Li, XJ1
Takadera, T1
Maki, T1
Hibino, H1
Mohri, T1
Kaneko, M1
Saito, Y1
Saito, H1
Matsumoto, T1
Matsuda, Y1
Vaught, JL1
Dionne, CA1
Angeles, TS1
Glicksman, MA1
Neff, NT1
Rotella, DP1
Kauer, JC1
Mallamo, JP1
Hudkins, RL1
Murakata, C1
Rundén, E1
Seglen, PO1
Haug, FM1
Ottersen, OP1
Wieloch, T1
Shamloo, M1
Laake, JH1

Other Studies

5 other studies available for staurosporine aglycone and Nerve Degeneration

ArticleYear
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway.
    Brain, behavior, and immunity, 2011, Volume: 25, Issue:1

    Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Count; Cell Survival; Chemokines; Corpu

2011
Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB.
    Brain research, 2008, May-19, Volume: 1210

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Apoptosis; Brain-Derived Neurotrophic Factor; Carb

2008
A cyclic AMP analog and high potassium prevent the death of cultured septal cholinergic neurons after nerve growth factor withdrawal.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:1

    Topics: Acetylcholinesterase; Animals; Bucladesine; Calcium Channel Blockers; Carbazoles; Cells, Cultured; C

1996
Neurotrophic 3,9-bis[(alkylthio)methyl]-and-bis(alkoxymethyl)-K-252a derivatives.
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Animals; Apoptosis; Carbazoles; Chick Embryo; Choline O-Acetyltransferase; Enzyme Inhibitors; Female

1997
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calci

1998