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staurosporine aglycone and Neoplasm Metastasis

staurosporine aglycone has been researched along with Neoplasm Metastasis in 4 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Chondrosarcoma is the primary malignancy of bone that is characterized by a potent capacity to invade locally and cause distant metastasis, and is therefore associated with poor prognoses."1.39Apoptosis signal-regulating kinase 1 is involved in brain-derived neurotrophic factor (BDNF)-enhanced cell motility and matrix metalloproteinase 1 expression in human chondrosarcoma cells. ( Chang, SL; Fong, YC; Hsu, CJ; Lin, CY; Tang, CH, 2013)
"The Y1235D mutation identified in metastases was shown to induce constitutive activation and a motile-invasive phenotype on transduced carcinoma cells."1.33Regulation of the wild-type and Y1235D mutant Met kinase activation. ( Cristiani, C; Isacchi, A; Kalisz, HM; Knapp, S; Perego, R; Rusconi, L; Schiering, N, 2005)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, CY1
Chang, SL1
Fong, YC1
Hsu, CJ1
Tang, CH1
Cristiani, C1
Rusconi, L1
Perego, R1
Schiering, N1
Kalisz, HM1
Knapp, S1
Isacchi, A1
Zolfaghari, A1
Djakiew, D1
Mohri, T1
Kameshita, I1
Suzuki, S1
Hioki, K1
Tokunaga, R1
Takatani, S1

Other Studies

4 other studies available for staurosporine aglycone and Neoplasm Metastasis

ArticleYear
Apoptosis signal-regulating kinase 1 is involved in brain-derived neurotrophic factor (BDNF)-enhanced cell motility and matrix metalloproteinase 1 expression in human chondrosarcoma cells.
    International journal of molecular sciences, 2013, Jul-25, Volume: 14, Issue:8

    Topics: Anthracenes; Bone Neoplasms; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Line, Tumor; Cell M

2013
Regulation of the wild-type and Y1235D mutant Met kinase activation.
    Biochemistry, 2005, Nov-01, Volume: 44, Issue:43

    Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Carbazoles; Enzyme Inhibitors; Gene Silencing;

2005
Inhibition of chemomigration of a human prostatic carcinoma cell (TSU-pr1) line by inhibition of epidermal growth factor receptor function.
    The Prostate, 1996, Volume: 28, Issue:4

    Topics: Alkaloids; Antibodies, Monoclonal; Carbazoles; Carcinogens; Carcinoma; Cell Movement; Dimethyl Sulfo

1996
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
    Cell structure and function, 1998, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine;

1998