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staurosporine aglycone and Glioma

staurosporine aglycone has been researched along with Glioma in 3 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Malignant glioma is the most aggressive primary brain tumor and has a poor survival rate."1.51The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma. ( Ge, H; Jiang, Y; Yang, Z; Yin, H; Zhang, Y, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yin, H1
Jiang, Y1
Zhang, Y1
Ge, H1
Yang, Z1
Chin, LS2
Murray, SF2
Zitnay, KM1
Rami, B1
Doherty, PF1
Singh, SK1

Other Studies

3 other studies available for staurosporine aglycone and Glioma

ArticleYear
The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Carba

2019
K252a inhibits proliferation of glioma cells by blocking platelet-derived growth factor signal transduction.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:5

    Topics: Apoptosis; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Division; DNA Primers; Enzyme Inhibit

1997
K252a induces cell cycle arrest and apoptosis by inhibiting Cdc2 and Cdc25c.
    Cancer investigation, 1999, Volume: 17, Issue:6

    Topics: Apoptosis; Blotting, Western; Carbazoles; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell

1999