staurosporine aglycone has been researched along with Glioma in 3 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant glioma is the most aggressive primary brain tumor and has a poor survival rate." | 1.51 | The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma. ( Ge, H; Jiang, Y; Yang, Z; Yin, H; Zhang, Y, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yin, H | 1 |
| Jiang, Y | 1 |
| Zhang, Y | 1 |
| Ge, H | 1 |
| Yang, Z | 1 |
| Chin, LS | 2 |
| Murray, SF | 2 |
| Zitnay, KM | 1 |
| Rami, B | 1 |
| Doherty, PF | 1 |
| Singh, SK | 1 |
3 other studies available for staurosporine aglycone and Glioma
| Article | Year |
|---|---|
The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Carba | 2019 |
K252a inhibits proliferation of glioma cells by blocking platelet-derived growth factor signal transduction.
Topics: Apoptosis; Brain-Derived Neurotrophic Factor; Carbazoles; Cell Division; DNA Primers; Enzyme Inhibit | 1997 |
K252a induces cell cycle arrest and apoptosis by inhibiting Cdc2 and Cdc25c.
Topics: Apoptosis; Blotting, Western; Carbazoles; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell | 1999 |