staurosporine aglycone has been researched along with Depressive Disorder in 6 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
Depressive Disorder: An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Curcumin is a major active component isolated from Curcuma longa." | 1.35 | Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB. ( Li, XJ; Li, YB; Li, YH; Wang, R; Wu, HL; Xu, Y, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gudasheva, TA | 1 |
| Tallerova, AV | 1 |
| Mezhlumyan, AG | 1 |
| Antipova, TA | 1 |
| Logvinov, IO | 1 |
| Firsova, YN | 1 |
| Povarnina, PY | 1 |
| Seredenin, SB | 1 |
| Wang, M | 1 |
| Zhou, W | 1 |
| Zhou, X | 1 |
| Zhuang, F | 1 |
| Chen, Q | 1 |
| Li, M | 1 |
| Ma, T | 1 |
| Gu, S | 1 |
| Luo, L | 1 |
| Liu, XL | 1 |
| Mu, RH | 1 |
| Wu, YJ | 1 |
| Liu, BB | 1 |
| Geng, D | 1 |
| Liu, Q | 1 |
| Yi, LT | 1 |
| Liu, WX | 1 |
| Wang, J | 1 |
| Xie, ZM | 1 |
| Xu, N | 1 |
| Zhang, GF | 1 |
| Jia, M | 1 |
| Zhou, ZQ | 1 |
| Hashimoto, K | 1 |
| Yang, JJ | 1 |
| Shah, AP | 1 |
| Carreno, FR | 1 |
| Wu, H | 1 |
| Chung, YA | 1 |
| Frazer, A | 1 |
| Wang, R | 1 |
| Li, YB | 1 |
| Li, YH | 1 |
| Xu, Y | 1 |
| Wu, HL | 1 |
| Li, XJ | 1 |
6 other studies available for staurosporine aglycone and Depressive Disorder
| Article | Year |
|---|---|
Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress.
Topics: Administration, Oral; Animals; Antidepressive Agents; Behavior, Animal; Biomimetic Materials; Brain- | 2021 |
Antidepressant-like effects of alarin produced by activation of TrkB receptor signaling pathways in chronic stress mice.
Topics: Animals; Antidepressive Agents; Brain; Carbazoles; Cyclic AMP Response Element-Binding Protein; Depr | 2015 |
Hippocampal BDNF signaling restored with chronic asiaticoside treatment in depression-like mice.
Topics: Animals; Antidepressive Agents; Carbazoles; Central Nervous System Agents; Chronic Disease; Depressi | 2015 |
Regulation of glutamate transporter 1 via BDNF-TrkB signaling plays a role in the anti-apoptotic and antidepressant effects of ketamine in chronic unpredictable stress model of depression.
Topics: Animals; Antidepressive Agents; Apoptosis; Astrocytes; Behavior, Animal; Brain-Derived Neurotrophic | 2016 |
Role of TrkB in the anxiolytic-like and antidepressant-like effects of vagal nerve stimulation: Comparison with desipramine.
Topics: Adrenergic Uptake Inhibitors; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiet | 2016 |
Curcumin protects against glutamate excitotoxicity in rat cerebral cortical neurons by increasing brain-derived neurotrophic factor level and activating TrkB.
Topics: Animals; Animals, Newborn; Antidepressive Agents; Apoptosis; Brain-Derived Neurotrophic Factor; Carb | 2008 |