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staurosporine aglycone and Asthma

staurosporine aglycone has been researched along with Asthma in 2 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"We conclude that substance P plays a role in the induction of AHR in our model for allergic asthma which is most likely mediated by NGF."7.73Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA. ( Braun, A; de Vries, A; Dessing, MC; Engels, F; Fischer, A; Groneberg, DA; Henricks, PA; Leusink-Muis, T; McGregor, GP; Nijkamp, FP, 2006)
"We conclude that substance P plays a role in the induction of AHR in our model for allergic asthma which is most likely mediated by NGF."3.73Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA. ( Braun, A; de Vries, A; Dessing, MC; Engels, F; Fischer, A; Groneberg, DA; Henricks, PA; Leusink-Muis, T; McGregor, GP; Nijkamp, FP, 2006)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wu, ZX1
Benders, KB1
Hunter, DD1
Dey, RD1
de Vries, A1
Engels, F1
Henricks, PA1
Leusink-Muis, T1
McGregor, GP1
Braun, A1
Groneberg, DA1
Dessing, MC1
Nijkamp, FP1
Fischer, A1

Other Studies

2 other studies available for staurosporine aglycone and Asthma

ArticleYear
Early postnatal exposure of mice to side-steam tobacco smoke increases neuropeptide Y in lung.
    American journal of physiology. Lung cellular and molecular physiology, 2012, Jan-01, Volume: 302, Issue:1

    Topics: Age Factors; Airway Resistance; Animals; Animals, Newborn; Asthma; Carbazoles; Indole Alkaloids; Met

2012
Airway hyper-responsiveness in allergic asthma in guinea-pigs is mediated by nerve growth factor via the induction of substance P: a potential role for trkA.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2006, Volume: 36, Issue:9

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbazoles; Disease Models

2006