staurosporine aglycone has been researched along with Allodynia in 14 studies
staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor
| Excerpt | Relevance | Reference |
|---|---|---|
| "ET-1 induced facial heat hyperalgesia that persisted up to 6h and was prevented by BQ-123, BQ-788 or by intraganglionar RTX injection." | 1.46 | Mechanisms involved in facial heat hyperalgesia induced by endothelin-1 in female rats. ( Araya, EI; Chichorro, JG; Dos Reis, RC; Kopruszinski, CM; Nones, CFM; Oliveira, LL; Rae, GA; Souza, RF, 2017) |
| "Heat hyperalgesia induced by peripheral injection of CFA was significantly reversed by roscovitine, TrkB-IgG, and the TrkB inhibitor K252a, respectively." | 1.40 | The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats. ( Huang, JL; Lu, H; Shao, HJ; Wang, WY; Xue, QS; Yu, BW; Zhang, HH; Zhang, S; Zhang, XQ, 2014) |
| "Mechanical hyperalgesia continued for 28 days at a lesion in the BLG, 21 days in PLG and 5 days in SLG after treatments, respectively." | 1.38 | Nerve growth factor and associated nerve sprouting contribute to local mechanical hyperalgesia in a rat model of bone injury. ( Hayashi, K; Hori, K; Ichiyanagi, M; Ozaki, N; Shiraishi, Y; Sugiura, Y; Yasui, M, 2012) |
| "Visceral hyperalgesia is a multifactorial gastrointestinal disorder which featured with alterations of abdominal motility and/or gut sensitivity, and is believed to be triggered by environmental stressor or psychological factors." | 1.38 | Nerve growth factor-mediated neuronal plasticity in spinal cord contributes to neonatal maternal separation-induced visceral hypersensitivity in rats. ( Bian, ZX; Sung, JJ; Tsang, SW; Wu, J; Zhao, M, 2012) |
| "CFA injection induced heat hyperalgesia of the ipsilateral whisker pad skin." | 1.37 | Nerve growth factor contribution via transient receptor potential vanilloid 1 to ectopic orofacial pain. ( Asano, M; Hitomi, S; Honda, K; Iwata, K; Katagiri, A; Omagari, D; Shinoda, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 9 (64.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Oga, S | 1 |
| Goto, K | 1 |
| Sakamoto, J | 1 |
| Honda, Y | 1 |
| Sasaki, R | 1 |
| Ishikawa, K | 1 |
| Kataoka, H | 1 |
| Nakano, J | 1 |
| Origuchi, T | 1 |
| Okita, M | 1 |
| Souza, RF | 1 |
| Oliveira, LL | 1 |
| Nones, CFM | 1 |
| Dos Reis, RC | 1 |
| Araya, EI | 1 |
| Kopruszinski, CM | 1 |
| Rae, GA | 1 |
| Chichorro, JG | 1 |
| Takeda, M | 1 |
| Takahashi, M | 1 |
| Matsumoto, S | 1 |
| Zhang, HH | 1 |
| Zhang, XQ | 1 |
| Xue, QS | 1 |
| Huang, JL | 1 |
| Zhang, S | 1 |
| Shao, HJ | 1 |
| Lu, H | 1 |
| Wang, WY | 1 |
| Yu, BW | 1 |
| Khodorova, A | 1 |
| Nicol, GD | 1 |
| Strichartz, G | 1 |
| Pelegrini-da-Silva, A | 1 |
| Oliveira, MC | 1 |
| Parada, CA | 1 |
| Tambeli, CH | 1 |
| Shinoda, M | 1 |
| Asano, M | 1 |
| Omagari, D | 1 |
| Honda, K | 1 |
| Hitomi, S | 1 |
| Katagiri, A | 1 |
| Iwata, K | 1 |
| Hayashi, K | 2 |
| Ozaki, N | 2 |
| Kawakita, K | 1 |
| Itoh, K | 1 |
| Mizumura, K | 1 |
| Furukawa, K | 1 |
| Yasui, M | 2 |
| Hori, K | 2 |
| Yi, SQ | 1 |
| Yamaguchi, T | 1 |
| Sugiura, Y | 2 |
| Shiraishi, Y | 1 |
| Ichiyanagi, M | 1 |
| Tsang, SW | 1 |
| Zhao, M | 1 |
| Wu, J | 1 |
| Sung, JJ | 1 |
| Bian, ZX | 1 |
| Li, Q | 1 |
| Zhang, X | 1 |
| Liu, K | 1 |
| Gong, L | 1 |
| Li, J | 1 |
| Yao, W | 1 |
| Liu, C | 1 |
| Yu, S | 1 |
| Li, Y | 1 |
| Yao, Z | 1 |
| Ma, X | 1 |
| Sung, B | 1 |
| Lim, G | 1 |
| Mao, J | 1 |
| Zhang, W | 1 |
| Liu, LY | 1 |
| Xu, TL | 1 |
| Guerios, SD | 1 |
| Wang, ZY | 1 |
| Boldon, K | 1 |
| Bushman, W | 1 |
| Bjorling, DE | 1 |
14 other studies available for staurosporine aglycone and Allodynia
| Article | Year |
|---|---|
Mechanisms underlying immobilization-induced muscle pain in rats.
Topics: Animals; Carbazoles; Casts, Surgical; Enzyme Inhibitors; Hindlimb; Hyperalgesia; Immobilization; Ind | 2020 |
Mechanisms involved in facial heat hyperalgesia induced by endothelin-1 in female rats.
Topics: Animals; Carbazoles; Diterpenes; Endothelin-1; Face; Female; Hot Temperature; Hyperalgesia; Indole A | 2017 |
Inflammation enhanced brain-derived neurotrophic factor-induced suppression of the voltage-gated potassium currents in small-diameter trigeminal ganglion neurons projecting to the trigeminal nucleus interpolaris/caudalis transition zone.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Enzyme Inhibitors; Freund's Adjuvant; Hypera | 2014 |
The BDNF/TrkB signaling pathway is involved in heat hyperalgesia mediated by Cdk5 in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cyclin-Dependent Kinase 5; Freund's Adjuvant | 2014 |
The TrkA receptor mediates experimental thermal hyperalgesia produced by nerve growth factor: Modulation by the p75 neurotrophin receptor.
Topics: Analgesics; Aniline Compounds; Animals; Antibodies; Benzylidene Compounds; Carbazoles; Disease Model | 2017 |
Nerve growth factor acts with the beta2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia.
Topics: Adrenergic beta-2 Receptor Antagonists; Animals; Behavior, Animal; Carbazoles; Enzyme Inhibitors; Ep | 2008 |
Nerve growth factor contribution via transient receptor potential vanilloid 1 to ectopic orofacial pain.
Topics: Analysis of Variance; Animals; Antibodies, Neutralizing; Behavior, Animal; Blotting, Western; Carbaz | 2011 |
Involvement of NGF in the rat model of persistent muscle pain associated with taut band.
Topics: Analysis of Variance; Animals; Carbazoles; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked | 2011 |
Nerve growth factor and associated nerve sprouting contribute to local mechanical hyperalgesia in a rat model of bone injury.
Topics: Animals; Antibodies, Neutralizing; Behavior, Animal; Bone and Bones; Carbazoles; Disease Models, Ani | 2012 |
Nerve growth factor-mediated neuronal plasticity in spinal cord contributes to neonatal maternal separation-induced visceral hypersensitivity in rats.
Topics: Animals; Animals, Newborn; Anxiety, Separation; Blotting, Western; Calcitonin Gene-Related Peptide; | 2012 |
Brain-derived neurotrophic factor exerts antinociceptive effects by reducing excitability of colon-projecting dorsal root ganglion neurons in the colorectal distention-evoked visceral pain model.
Topics: Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cells, Cultured; Dilatation, Pathologic; Gan | 2012 |
Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats.
Topics: Amino Acid Transport System X-AG; Animals; Behavior, Animal; Biological Transport; Carbazoles; Const | 2003 |
Reduced potassium-chloride co-transporter expression in spinal cord dorsal horn neurons contributes to inflammatory pain hypersensitivity in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Carbazoles; Enzyme Inhibitors; Freund's Adjuvant; F | 2008 |
Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats.
Topics: Acrolein; Animals; Carbazoles; Cystitis; Drug Administration Routes; Enzyme Inhibitors; Female; Gene | 2008 |