Page last updated: 2024-10-29

staurosporine aglycone and Adrenal Cancer

staurosporine aglycone has been researched along with Adrenal Cancer in 15 studies

staurosporine aglycone: metabolite from culture broth of Nocardiopsis sp.; a neurotrophin antag; inhibits BDNF TrkB receptor

Research Excerpts

ExcerptRelevanceReference
" A tyrosine kinase inhibitor, herbimycin, inhibited neurite outgrowth of rat pheochromocytoma PC12 cells induced by NGF but not that by dibutyryl-cAMP."3.68Specific inhibition of NGF receptor tyrosine kinase activity by K-252a. ( Hashimoto, Y; Hattori, S; Muroya, K; Nakamura, S, 1992)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's9 (60.00)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Macdonald, NJ1
Taglialatela, G1
Sugimoto, T1
Kuroda, H1
Horii, Y1
Moritake, H1
Tanaka, T1
Hattori, S2
Muroya, K1
Hashimoto, Y1
Nakamura, S1
Knüsel, B1
Kaplan, DR1
Winslow, JW1
Rosenthal, A1
Burton, LE1
Beck, KD1
Rabin, S1
Nikolics, K1
Hefti, F1
Loeb, DM1
Maragos, J1
Martin-Zanca, D1
Chao, MV1
Parada, LF1
Greene, LA2
Rukenstein, A1
Rydel, RE1
Nagashima, K1
Nakanishi, S1
Matsuda, Y3
Tischler, AS1
Ruzicka, LA1
Perlman, RL1
Nikodijevic, B1
Creveling, CR1
Koizumi, S4
Guroff, G4
Sano, M1
Nishiyama, K1
Kitajima, S1
Hashimoto, S1
Hagino, A1
Lazarovici, P2
Levi, BZ1
Lelkes, PI1
Fujita, K2
Ozato, K1
Smith, DS1
King, CS1
Pearson, E1
Gittinger, CK1
Landreth, GE1
Rausch, DM1
Dickens, G1
Doll, S1
Rudkin, BB1
Tocco, M1
Eiden, LE1
Contreras, ML1
Hama, T1

Other Studies

15 other studies available for staurosporine aglycone and Adrenal Cancer

ArticleYear
Tumor necrosis factor-alpha and nerve growth factor synergistically induce iNOS in pheochromocytoma cells.
    Neuroreport, 2000, Nov-09, Volume: 11, Issue:16

    Topics: Adrenal Gland Neoplasms; Animals; Carbazoles; Dose-Response Relationship, Drug; Drug Synergism; Enzy

2000
Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Carbazoles; Cell Differentiation; Cell Survival; Child, Preschool;

2001
Specific inhibition of NGF receptor tyrosine kinase activity by K-252a.
    Biochimica et biophysica acta, 1992, Jun-29, Volume: 1135, Issue:3

    Topics: Adrenal Gland Neoplasms; Amino Acid Sequence; Animals; Benzoquinones; Bucladesine; Carbazoles; Glyco

1992
K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3.
    Journal of neurochemistry, 1992, Volume: 59, Issue:2

    Topics: Adrenal Gland Neoplasms; Alkaloids; Animals; Brain-Derived Neurotrophic Factor; Carbazoles; Cells, C

1992
The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines.
    Cell, 1991, Sep-06, Volume: 66, Issue:5

    Topics: Adrenal Gland Neoplasms; Animals; Blotting, Northern; Carbazoles; Cell Differentiation; Cell Divisio

1991
Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:8

    Topics: Adrenal Gland Neoplasms; Animals; Blood; Carbazoles; Cell Survival; Culture Media; Indole Alkaloids;

1991
Inhibition of nerve growth factor-induced neurite outgrowth of PC12 cells by a protein kinase inhibitor which does not permeate the cell membrane.
    FEBS letters, 1991, Nov-18, Volume: 293, Issue:1-2

    Topics: Adrenal Gland Neoplasms; Animals; Carbazoles; Cell Division; Cell Line; Cell Membrane Permeability;

1991
Mimicry and inhibition of nerve growth factor effects: interactions of staurosporine, forskolin, and K252a in PC12 cells and normal rat chromaffin cells in vitro.
    Journal of neurochemistry, 1990, Volume: 55, Issue:4

    Topics: Adrenal Gland Neoplasms; Adrenal Medulla; Alkaloids; Animals; Animals, Newborn; Axons; Carbazoles; C

1990
Nerve growth factor and K-252a increase catecholamine release from PC12 cells.
    Journal of neuroscience research, 1990, Volume: 26, Issue:3

    Topics: Adrenal Gland Neoplasms; Animals; Carbazoles; Catecholamines; Chromatography, High Pressure Liquid;

1990
A nerve growth factor-dependent protein kinase that phosphorylates microtubule-associated proteins in vitro: possible involvement of its activity in the outgrowth of neurites from PC12 cells.
    Journal of neurochemistry, 1990, Volume: 55, Issue:2

    Topics: Adrenal Gland Neoplasms; Animals; Axons; Bucladesine; Carbazoles; Indole Alkaloids; Kinetics; Magnes

1990
Nerve growth factor-induced transient increase in the phosphorylation of ribosomal protein S6 mediated through a mechanism independent of cyclic AMP-dependent protein kinase and protein kinase C.
    Journal of neurochemistry, 1990, Volume: 55, Issue:3

    Topics: Adenosine Triphosphate; Adrenal Gland Neoplasms; Animals; Bucladesine; Carbazoles; Cell-Free System;

1990
K-252a inhibits the increase in c-fos transcription and the increase in intracellular calcium produced by nerve growth factor in PC12 cells.
    Journal of neuroscience research, 1989, Volume: 23, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Calcium; Carbazoles; Cell Line; DNA-Binding Proteins; Indole Alkal

1989
Selective inhibition of nerve growth factor-stimulated protein kinases by K-252a and 5'-S-methyladenosine in PC12 cells.
    Journal of neurochemistry, 1989, Volume: 53, Issue:3

    Topics: Adenosine; Adrenal Gland Neoplasms; Animals; Carbazoles; Cyclic AMP; Enzyme Activation; Epidermal Gr

1989
Differentiation of PC12 cells with v-src: comparison with nerve growth factor.
    Journal of neuroscience research, 1989, Volume: 24, Issue:1

    Topics: Adrenal Gland Neoplasms; Amphibian Proteins; Animals; Binding, Competitive; Carbazoles; Carrier Prot

1989
K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:2

    Topics: Adrenal Gland Neoplasms; Carbazoles; Indole Alkaloids; Nerve Growth Factors; Pheochromocytoma

1988