st-638 and Leukemia--Myeloid

st-638 has been researched along with Leukemia--Myeloid* in 1 studies

Other Studies

1 other study(ies) available for st-638 and Leukemia--Myeloid

ArticleYear
Induction of phagocytic activity of M1 cells by an inhibitor of vacuolar H+-ATPase, bafilomycin A1.
    FEBS letters, 1994, Jan-17, Volume: 337, Issue:3

    Bafilomycin A1, a selective inhibitor of vacuolar H+-ATPase, time- and dose-dependently induced the differentiation of M1 cells, a murine myeloid leukemic cell line, into macrophage-like cells as revealed by the phagocytosis of polystyrene latex particles. This differentiation was inhibited not only by actinomycin D and cycloheximide but also by ST-638 (an inhibitor of tyrosine kinase). However, it was affected neither by K-252a (an inhibitor of C-kinase) nor by H-89 (an inhibitor of A-kinase), in contrast to the M1 cell differentiation induced by leukemia inhibitory factor (LIF). Okadaic acid inhibited both the bafilomycin A1-induced and LIF-induced differentiation of M1 cells.

    Topics: Animals; Anti-Bacterial Agents; Carbazoles; Cinnamates; Ethers, Cyclic; Growth Inhibitors; Indole Alkaloids; Interleukin-6; Isoquinolines; Leukemia Inhibitory Factor; Leukemia, Myeloid; Lymphokines; Macrolides; Macrophages; Mice; Okadaic Acid; Phagocytosis; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Protein Kinase C; Protein Kinase Inhibitors; Proton-Translocating ATPases; RNA; Sulfides; Sulfonamides; Tumor Cells, Cultured; Vacuoles

1994