sr141716 has been researched along with Muscle Contraction in 30 studies
*Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 17 (56.67) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, P; Fernando, SR; Lan, R; Lin, S; Liu, Q; Makriyannis, A; McCallion, D; Pertwee, R | 1 |
| Francisco, ME; Gilliam, AF; Mitchell, RA; Pertwee, RG; Rider, SL; Seltzman, HH; Stevenson, LA; Thomas, BF | 1 |
| Angus, JA; Mazeh, AC; Wright, CE | 1 |
| Donnerer, J; Liebmann, I | 1 |
| Andersson, KE; Campeau, L; Füllhase, C; Gratzke, C; Hedlund, P; Hennenberg, M; Sibaev, A; Stief, C; Storr, M | 1 |
| Kemmer, M; Kreis, ME; Li, Y; Müller, M; Qian, G; Sibaev, A; Storr, M; Yüce, B | 1 |
| Makwana, R; Molleman, A; Parsons, ME | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Kaya, T; Sarac, B; Sencan, M; Turan, M | 1 |
| Berkley, KJ; Dmitrieva, N | 1 |
| Adinolfi, B; Breschi, MC; Calderone, V; Martinotti, E; Nieri, P; Testai, L | 1 |
| Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Mascolo, N | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Yamada, Y; Yoshihara, S | 1 |
| Amico, MC; Morrone, LA; Palmery, M; Romanelli, L; Tucci, P; Valeri, P | 1 |
| Abe, T; Arisaka, O; Morimoto, H; Ohori, M; Yamada, Y; Yoshihara, S | 1 |
| Bianchetti, A; Croci, T; Di Marzo, V; Di Palo, S; Ferla, G; Guagnini, F; Matias, I; Mukenge, S; Valenti, M | 1 |
| Bueno, L; Fioramonti, J; Sanson, M | 1 |
| Baldassano, S; Mule', F; Serio, R | 1 |
| Griffin, G; Huffman, JW; Lainton, JA; Pertwee, RG | 1 |
| Coutts, AA; Fernando, SR; Nash, JE; Pertwee, RG | 1 |
| Aanonsen, L; Hargreaves, KM; Richardson, JD | 1 |
| Brockie, HC; Fernando, SR; Pertwee, RG; Razdan, RK; Ross, RA; Saha, B | 1 |
| Aureggi, G; Croci, T; Ferla, G; Guagnini, F; Le Fur, G; Maffrand, JP; Manara, L; Mukenge, S; Rinaldi-Carmona, M | 1 |
| Oriowo, MA; Yousif, MH | 1 |
| Capasso, F; Izzo, AA; Mascolo, N; Tonini, M | 1 |
| Eglen, RM; Luong, LA; MacLennan, SJ; Martin, GR; Martin, RS; Welsh, NJ | 1 |
| Chuang, H; Högestätt, ED; Julius, D; Movahed, P; Zygmunt, PM | 1 |
| Calignano, A; Désarnaud, F; Freund, TF; Giuffrida, A; Kátona, I; La Rana, G; Mackie, K; Piomelli, D | 1 |
| Brockie, HC; Craib, SJ; Di Marzo, V; Gibson, TM; Leslie, M; Pashmi, G; Pertwee, RG; Ross, RA | 1 |
| Craib, SJ; Ellington, HC; Pertwee, RG; Ross, RA | 1 |
| Erbelding, D; Kilbinger, H; Mang, CF | 1 |
30 other study(ies) available for sr141716 and Muscle Contraction
| Article | Year |
|---|---|
Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists.
Topics: Animals; Cannabinoids; Guinea Pigs; Humans; In Vitro Techniques; Intestine, Small; Male; Mice; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Piperidines; Prosencephalon; Pyrazoles; Rats; Receptors, Cannabinoid; Receptors, Drug; Spleen; Structure-Activity Relationship; Vas Deferens | 1999 |
Synthesis and structure-activity relationships of amide and hydrazide analogues of the cannabinoid CB(1) receptor antagonist N-(piperidinyl)- 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716).
Topics: Animals; Binding, Competitive; Cannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Mice; Models, Molecular; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrazoles; Quantitative Structure-Activity Relationship; Radioligand Assay; Rats; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vas Deferens | 2002 |
Pharmacological characterisation of the CB
Topics: Adenosine Triphosphate; Animals; Biological Assay; Cannabidiol; Cannabinoid Receptor Antagonists; Male; Muscle Contraction; Norepinephrine; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Vas Deferens | 2021 |
Effect of CB1 Ligands on Neurogenic and Myogenic Contractile Responses in the Guinea-Pig Ileum.
Topics: Animals; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Ileum; Ligands; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2018 |
Bladder function in a cannabinoid receptor type 1 knockout mouse.
Topics: Animals; Cannabinoid Receptor Antagonists; Carbachol; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Urinary Bladder; Urination; Urodynamics | 2014 |
Cannabinoid 1 receptors modulate intestinal sensory and motor function in rat.
Topics: Animals; Benzoxazines; Bradykinin; Dose-Response Relationship, Drug; Electrophysiology; Enteric Nervous System; Gastrointestinal Motility; Intestines; Male; Morpholines; Motor Neurons; Muscle Contraction; Myenteric Plexus; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Sensory Receptor Cells; Serotonin | 2010 |
Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Dronabinol; Drug Inverse Agonism; Guinea Pigs; Ileum; Muscle Contraction; Myenteric Plexus; Piperidines; Pyrans; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant | 2010 |
Effects of cannabinoid agonists on sheep sphincter of oddi in vitro.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoids; Carbachol; Cyclic GMP; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Piperidines; Pyrazoles; Rimonabant; Sheep; Sphincter of Oddi | 2011 |
Contrasting effects of WIN 55212-2 on motility of the rat bladder and uterus.
Topics: Administration, Intravesical; Analgesics; Animals; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Catheterization; Dose-Response Relationship, Drug; Female; Injections, Intra-Arterial; Injections, Intravenous; Metestrus; Morpholines; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Naphthalenes; Organ Specificity; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Rimonabant; Turpentine; Urinary Bladder; Urination; Uterus | 2002 |
R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Atropine; Benzoxazines; Cannabinoid Receptor Modulators; Capsaicin; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Trachea | 2003 |
Inhibitory effect of the antidepressant St. John's wort (hypericum perforatum) on rat bladder contractility in vitro.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Anthracenes; Antidepressive Agents; Atropine; Bridged Bicyclo Compounds; Capsaicin; Depression; Electric Stimulation; Female; Haloperidol; Hypericum; Kaempferols; Male; Methysergide; Muscle Contraction; Muscle, Smooth; Naloxone; Perylene; Phentolamine; Phloroglucinol; Piperidines; Plant Extracts; Propranolol; Pyrazoles; Quercetin; Rats; Rats, Wistar; Rimonabant; Rutin; Terpenes; Tetrodotoxin; Urinary Bladder; Urinary Incontinence; Verapamil | 2004 |
Cannabinoid receptor agonists inhibit sensory nerve activation in guinea pig airways.
Topics: Analysis of Variance; Animals; Benzoxazines; Camphanes; Cannabinoid Receptor Antagonists; Disease Models, Animal; Electric Stimulation; Guinea Pigs; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Neurokinin A; Piperidines; Probability; Pyrazoles; Respiratory Muscles; Rimonabant; Sensitivity and Specificity; Sensory Receptor Cells | 2004 |
Involvement of the cannabinoid CB1 receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response.
Topics: Acute Disease; Adenosine A1 Receptor Antagonists; Analgesics, Opioid; Animals; Benzoxazines; Cholecystokinin; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naloxone; Naphthalenes; Narcotic Antagonists; Neurons; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rimonabant; Substance Withdrawal Syndrome; Theophylline | 2005 |
Endogenous cannabinoid receptor agonists inhibit neurogenic inflammations in guinea pig airways.
Topics: Amides; Animals; Arachidonic Acids; Bronchi; Bronchoconstriction; Calcium Channel Blockers; Camphanes; Cannabinoid Receptor Agonists; Capsaicin; Electric Stimulation; Endocannabinoids; Ethanolamines; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nerve Fibers, Unmyelinated; Neurogenic Inflammation; Organ Culture Techniques; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Receptors, Cannabinoid; Rimonabant; Substance P | 2005 |
Neural contractions in colonic strips from patients with diverticular disease: role of endocannabinoids and substance P.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Modulators; Case-Control Studies; Colon; Diverticulum; Endocannabinoids; Female; Glycerides; Humans; Imidazoles; Isoproterenol; Male; Middle Aged; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Neurokinin-1 Receptor Antagonists; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyrazoles; Quinuclidines; Rimonabant; Substance P; Tetrodotoxin | 2006 |
Involvement of cannabinoid receptors in inflammatory hypersensitivity to colonic distension in rats.
Topics: Animals; Benzoxazines; Calcium Channel Blockers; Camphanes; Colitis; Colon; Dose-Response Relationship, Drug; Indoles; Inflammation; Male; Manometry; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Nociceptors; Pain; Piperidines; Pressure; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Rimonabant; Trinitrobenzenesulfonic Acid | 2006 |
Cannabinoid CB(1) receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle.
Topics: Animals; Apamin; Arachidonic Acids; Atropine; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Endocannabinoids; Hexamethonium; Ileum; In Vitro Techniques; Indoles; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Tetrodotoxin | 2008 |
Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens.
Topics: Animals; Benzoxazines; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vas Deferens | 1995 |
Further evidence for the presence of cannabinoid CB1 receptors in guinea-pig small intestine.
Topics: Acetylcholine; Analgesics; Animals; Cyclohexanols; Dose-Response Relationship, Drug; Guinea Pigs; Intestine, Small; Male; Muscle Contraction; Myenteric Plexus; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1996 |
SR 141716A, a cannabinoid receptor antagonist, produces hyperalgesia in untreated mice.
Topics: Animals; Cannabinoids; Hyperalgesia; Injections, Spinal; Male; Mice; Muscle Contraction; Pain Measurement; Pain Threshold; Piperidines; Pyrazoles; Reaction Time; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1997 |
Comparison of cannabinoid binding sites in guinea-pig forebrain and small intestine.
Topics: Analgesics; Animals; Benzoxazines; Binding Sites; Binding, Competitive; Camphanes; Cyclohexanols; Dronabinol; Guinea Pigs; Intestine, Small; Kinetics; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naphthalenes; Neuromuscular Junction; Piperidines; Prosencephalon; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tritium | 1998 |
In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum.
Topics: Adult; Aged; Aged, 80 and over; Benzoxazines; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; Ileum; In Vitro Techniques; Male; Middle Aged; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Neurons; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetrodotoxin | 1998 |
Inhibitory effects of cannabinoid receptor ligands on electrically-evoked responses in rat isolated tracheal ring segments.
Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoids; Electric Stimulation; Endocannabinoids; In Vitro Techniques; Ligands; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetrodotoxin; Trachea | 1999 |
Modulation of peristalsis by cannabinoid CB(1) ligands in the isolated guinea-pig ileum.
Topics: Animals; Benzoxazines; Camphanes; Cannabinoids; Compliance; Cyclohexanols; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Morpholines; Muscle Contraction; Naphthalenes; Peristalsis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Benzoxazines; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Humans; In Vitro Techniques; Macaca fascicularis; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Receptors, Muscarinic; Rimonabant; Species Specificity; Swine; Urinary Bladder | 2000 |
The anandamide transport inhibitor AM404 activates vanilloid receptors.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoids; Capsaicin; Endocannabinoids; Female; Hepatic Artery; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oocytes; Patch-Clamp Techniques; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Drug; Rimonabant; Vasodilation; Xenopus | 2000 |
Bidirectional control of airway responsiveness by endogenous cannabinoids.
Topics: Animals; Arachidonic Acids; Axons; Bronchi; Bronchial Spasm; Bronchoconstriction; Cannabinoids; Capsaicin; Cough; Endocannabinoids; Guinea Pigs; Lung; Muscle Contraction; Muscle, Smooth; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2000 |
Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens.
Topics: Animals; Arachidonic Acids; Benzoxazines; Binding, Competitive; Biological Transport; Calcium; Calcium Channel Blockers; Cannabinoids; Capsaicin; CHO Cells; Cricetinae; Drug Interactions; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Phenylmethylsulfonyl Fluoride; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Radioligand Assay; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Structure-Activity Relationship; Transfection; TRPV Cation Channels; Vas Deferens | 2001 |
A possible role of lipoxygenase in the activation of vanilloid receptors by anandamide in the guinea-pig bronchus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Bronchi; Calcium Channel Blockers; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Fatty Acids, Unsaturated; Guinea Pigs; Hydrazines; In Vitro Techniques; Indomethacin; Lipoxygenase; Muscle Contraction; Oxazepines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Drug; Rimonabant; Thiorphan | 2001 |
Differential effects of anandamide on acetylcholine release in the guinea-pig ileum mediated via vanilloid and non-CB1 cannabinoid receptors.
Topics: Acetylcholine; Animals; Arachidonic Acids; Camphanes; Capsaicin; Cyclohexanols; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Guinea Pigs; Ileum; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 2001 |