sr141716 has been researched along with Liver Steatosis in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 12 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amato, GS; Cortes, R; Harris, DL; Lefever, TW; Maitra, R; Manke, A; Runyon, SP; Snyder, RW; Vasukuttan, V; Wang, S; Wiethe, RW; Zhang, Y | 1 |
| Bae, SH; Chang, E; Kim, DH; Lee, DH; Park, CY; Yang, H | 1 |
| Chen, W; Chen, Z; Li, S; Wang, L; Xue, N; Zheng, Z | 1 |
| Bhanot, S; Chakravarty, K; Manchem, VP; McCaleb, ML; Monia, BP; Watts, LM; Yu, XX | 1 |
| Cinar, R; Earley, BJ; Godlewski, G; Jourdan, T; Kunos, G; Szanda, G; Tam, J; Zhou, L | 1 |
| Chang, CP; Chao, YS; Chen, PH; Hsiao, WC; Hung, MS; Lin, Y; Shia, KS; Wang, YT; Wu, CH; Yeh, YN | 1 |
| Atkinson, RD; DeLeve, LD; Kanel, GC; McCuskey, RS; Wang, X | 1 |
| Harrison, SA; Kashi, MR; Torres, DM | 1 |
| Bedogni, G; Chavez-Tapia, NC; Crocè, LS; Masutti, F; Tellez-Avila, FI; Tiribelli, C | 1 |
| Degrace, P; Demizieux, L; Djaouti, L; Gresti, J; Jourdan, T; Vergès, B | 1 |
| Lotersztajn, S; Mallat, A | 1 |
| Aouad, L; Bell-Anderson, KS; Caterson, ID; Farrell, GC; Larter, CZ; Phuyal, J; Sanz, FR; Williams, H | 1 |
| Botha, AJ; Crook, MA; Dar, A; McMahon, Z; Oben, J; Pendleton, S; Wierzbicki, AS | 1 |
| Degrace, P; Demizieux, L; Djaouti, L; Gaba, L; Gresti, J; Jourdan, T; Vergès, B | 1 |
| Bergholm, R; Hakkarainen, A; Kotronen, A; Lundbom, J; Lundbom, N; Rissanen, A; Santos, A; Sevastianova, K; Tiikkainen, M; Urjansson, M; Yki-Järvinen, H | 1 |
| Deveaux, V; Hezode, C; Lotersztajn, S; Mallat, A; Teixeira-Clerc, F; Tran van Nhieu, J | 1 |
| Arnone, M; Bensaid, M; Chabbert, M; Croci, T; Cruccioli, N; Elachouri, G; Gallas, JF; Gary-Bobo, M; Herbert, JM; Janiak, P; Lacheretz, F; Le Fur, G; Maffrand, JP; Marini, P; Oury-Donat, F; Pfersdorff, C; Ravinet-Trillou, C; Roque, C; Scatton, B; Soubrié, P | 1 |
| Banasch, M; Goetze, O; Meier, JJ; Schmidt, WE | 1 |
3 review(s) available for sr141716 and Liver Steatosis
| Article | Year |
|---|---|
Current and emerging therapies in nonalcoholic fatty liver disease.
Topics: Animals; Antioxidants; Bariatric Surgery; Body Mass Index; Cannabinoids; Cholagogues and Choleretics; Comorbidity; Fatty Liver; Glucagon-Like Peptide 1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Insulin Resistance; Lactones; Life Style; Metformin; Obesity; Orlistat; Piperidines; Pyrazoles; Rimonabant; Thiazolidinediones; Treatment Outcome; Ursodeoxycholic Acid; Weight Loss | 2008 |
Systematic review and meta-analysis on the adverse events of rimonabant treatment: considerations for its potential use in hepatology.
Topics: Cannabinoid Receptor Antagonists; Fatty Liver; Humans; Mental Disorders; Nervous System Diseases; Piperidines; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Treatment Outcome | 2009 |
Endocannabinoids and their role in fatty liver disease.
Topics: Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Endocannabinoids; Fatty Liver; Humans; Hypertension, Portal; Inflammation; Insulin Resistance; Liver Cirrhosis; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant | 2010 |
1 trial(s) available for sr141716 and Liver Steatosis
| Article | Year |
|---|---|
CB(1) blockade-induced weight loss over 48 weeks decreases liver fat in proportion to weight loss in humans.
Topics: Adult; Aged; Cannabinoid Receptor Antagonists; Double-Blind Method; Fatty Liver; Female; Finland; Humans; Liver; Male; Metabolic Syndrome; Middle Aged; Obesity; Piperidines; Pyrazoles; Retrospective Studies; Rimonabant; Treatment Outcome; Weight Loss | 2013 |
14 other study(ies) available for sr141716 and Liver Steatosis
| Article | Year |
|---|---|
Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.
Topics: Alcohols; Animals; Cannabinoid Receptor Antagonists; Fatty Liver; Female; Humans; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Protein Conformation; Receptor, Cannabinoid, CB1; Structure-Activity Relationship; Tissue Distribution | 2018 |
CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes.
Topics: Adenylate Kinase; Animals; Diabetes Mellitus, Experimental; Fatty Liver; Inflammation; Liver; NF-E2-Related Factor 2; Obesity; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Rimonabant; Severity of Illness Index; Signal Transduction | 2018 |
Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats.
Topics: Adipose Tissue; Animals; Animals, Newborn; Cannabinoid Receptor Antagonists; Fatty Liver; Female; Glucose Intolerance; Hyperlipidemias; Insulin Resistance; Liver; Male; Obesity; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Insulin; Rimonabant; Sodium Glutamate | 2013 |
Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice.
Topics: Adiposity; Animals; Basal Metabolism; Bile Acids and Salts; Body Weight; Caloric Restriction; Diet; Drug Therapy, Combination; Fatty Acids; Fatty Liver; Feeding Behavior; Fibroblast Growth Factors; Gene Expression Regulation; Hepatocytes; Insulin; Liver; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Oligonucleotides, Antisense; Oxidation-Reduction; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Fibroblast Growth Factor, Type 4; Rimonabant | 2013 |
Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity.
Topics: Adiponectin; Adiposity; Animals; Body Weight; Cannabinoid Receptor Antagonists; Diet, High-Fat; Energy Intake; Fatty Liver; Leptin; Lipid Metabolism; Lipids; Liver; Mice; Mice, Knockout; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2014 |
A novel peripheral cannabinoid receptor 1 antagonist, BPR0912, reduces weight independently of food intake and modulates thermogenesis.
Topics: Adipose Tissue, Brown; Adipose Tissue, White; Animals; Anti-Obesity Agents; Cannabinoid Receptor Antagonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eating; Energy Metabolism; Fatty Liver; Ion Channels; Lipolysis; Male; Mice; Mice, Inbred C57BL; Mitochondrial Proteins; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Thermogenesis; Thiophenes; Uncoupling Protein 1; Weight Loss | 2015 |
Prevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis.
Topics: Actins; Animals; Apolipoprotein A-I; Body Weight; Cells, Cultured; Diet; Disease Models, Animal; Fatty Liver; Hepatocytes; Inflammation; Liver; Liver Cirrhosis; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Organ Size; Piperidines; Pyrazoles; Rimonabant | 2008 |
CB1 antagonism exerts specific molecular effects on visceral and subcutaneous fat and reverses liver steatosis in diet-induced obese mice.
Topics: Adiponectin; Adipose Tissue; Animal Feed; Animals; Apolipoproteins A; Apolipoproteins B; Body Weight; Cannabinoid Receptor Antagonists; Diet; Fatty Liver; Gene Expression Regulation; Liver; Mice; Mice, Obese; Obesity; Organ Size; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Sucrose | 2010 |
Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice.
Topics: Adipose Tissue; Animals; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Glucose Intolerance; Glucose Tolerance Test; Inflammation; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice; Obesity, Morbid; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2011 |
Rimonabant improves cholesterol, insulin resistance and markers of non-alcoholic fatty liver in morbidly obese patients: a retrospective cohort study.
Topics: Adult; Biomarkers; Cannabinoid Receptor Modulators; Cholesterol; Fatty Liver; Female; Humans; Hypercholesterolemia; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity, Morbid; Piperidines; Pyrazoles; Retrospective Studies; Rimonabant; Safety-Based Drug Withdrawals; Triglycerides; Weight Loss | 2011 |
Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: evidence from cultured explants.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Carbohydrate Metabolism; Cholesterol; Disease Models, Animal; Dyslipidemias; Fatty Liver; Gene Expression Regulation; Lipid Metabolism; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; Oxygen Consumption; Piperidines; Protein Kinases; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; RNA, Messenger; Tissue Culture Techniques | 2012 |
[Endocannabinoids: therapeutic perspectives in chronic liver diseases].
Topics: Animals; Appetite Depressants; Cannabinoid Receptor Modulators; Cannabinoids; Chronic Disease; Disease Models, Animal; Disease Progression; Endocannabinoids; Fatty Liver; Glycolysis; Hepatitis C, Chronic; Hepatocytes; Humans; Hypertension, Portal; Lipogenesis; Liver; Liver Cirrhosis; Liver Diseases; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2007 |
Rimonabant reduces obesity-associated hepatic steatosis and features of metabolic syndrome in obese Zucker fa/fa rats.
Topics: Animals; Cannabinoid Receptor Antagonists; Fatty Liver; Inflammation; Liver; Male; Metabolic Syndrome; Obesity; Piperidines; Pyrazoles; Rats; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction; Rimonabant; RNA; Tumor Necrosis Factor-alpha | 2007 |
Rimonabant as a novel therapeutic option for nonalcoholic steatohepatitis.
Topics: Adiponectin; Adult; Blood Glucose; Fatty Liver; Female; Humans; Insulin; Lipids; Liver; Mitochondria, Liver; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Severity of Illness Index; Treatment Outcome | 2007 |