Page last updated: 2024-08-26

sr141716 and Cannabis Abuse

sr141716 has been researched along with Cannabis Abuse in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (60.87)29.6817
2010's8 (34.78)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Crowe, MS; Gross, JD; Jones, MS; Kinsey, SG; McKitrick, AW; Nass, SR; Siderovski, DP; Trexler, KR1
Ahmad, U; Chen, X; Damaj, MI; Donvito, G; Jackson, KJ; Lichtman, AH; McIntosh, JM; Muldoon, PP; Zaveri, NT1
Bergman, J; Goldberg, SR; Justinova, Z; Le Foll, B; Makriyannis, A; Redhi, GH; Schindler, CW; Vemuri, K1
Abdullah, RA; Cravatt, BF; Falenski, KW; Lichtman, AH; Schlosburg, JE; Selley, DE; Sim-Selley, LJ; Smith, TH; Thorpe, AJ1
Diana, M; Lintas, A; Migliore, M; Spiga, S1
Lichtman, AH; Long, KA; Middleton, LS; Selley, DE; Sim-Selley, LJ; Varvel, SA; Wiebelhaus, JM; Wise, LE1
Baumann, MH; Bonnet, D; Darwin, WD; Goodwin, RS; Gorelick, DA; Huestis, MA; Kelly, DL; Ortemann-Renon, C; Schroeder, JR; Schwilke, E; Schwope, DM1
Bonnet, D; Darwin, WD; Goodwin, RS; Gorelick, DA; Huestis, MA; Kelly, DL; Liu, F; McMahon, RP; Ortemann-Renon, C; Schwilke, E; Schwope, DM1
Ginsburg, BC; Hruba, L; McMahon, LR; Schulze, DR1
Caulder, T; Hoffman, AF; Lupica, CR; Oz, M1
Deadwyler, SA; Hampson, RE; Kelly, EJ; Simeral, JD1
Nutt, D1
Lichtman, AH; Martin, BR1
Cannon, CP; Gelfand, EV1
Villares, J1
Bonnet, D; Boyd, SJ; Gorelick, DA; Heishman, SJ; Huestis, MA; Le Fur, G; Preston, KL1
Goldberg, SR; Justinova, Z; Munzar, P; Panlilio, LV; Redhi, GH; Tanda, G; Yasar, S1
Benyamina, A; Blecha, L; Lecacheux, M; Lukasiewcz, M; Reynaud, M1
Massi, P; Parolaro, D; Rubino, T; Viganò, D1
Frank, RA; Gorelick, DA; Heishman, SJ; Huestis, MA; Moolchan, ET; Nelson, RA; Preston, KL1
D'Souza, DC; Kosten, TR1
Filliol, D; Ghozland, S; Kieffer, BL; Maldonado, R; Matthes, HW; Simonin, F1
De Miguel, R; Fernández, B; Gomez, N; Guaza, C; Ramos, JA; Romero, EM; Sagredo, O; Urigüen, L; Viveros, MP1

Reviews

3 review(s) available for sr141716 and Cannabis Abuse

ArticleYear
Cannabinoid tolerance and dependence.
    Handbook of experimental pharmacology, 2005, Issue:168

    Topics: Animals; Cannabinoid Receptor Modulators; Cannabinoids; Drug Tolerance; Humans; Marijuana Abuse; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Substance Withdrawal Syndrome

2005
Rimonabant: a cannabinoid receptor type 1 blocker for management of multiple cardiometabolic risk factors.
    Journal of the American College of Cardiology, 2006, May-16, Volume: 47, Issue:10

    Topics: Animals; Atherosclerosis; Blood Glucose; Cannabinoid Receptor Modulators; Cardiovascular Diseases; Cardiovascular System; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Lipid Metabolism; Marijuana Abuse; Metabolic Syndrome; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Smoking Cessation

2006
Pharmacotherapy and psychotherapy in cannabis withdrawal and dependence.
    Expert review of neurotherapeutics, 2008, Volume: 8, Issue:3

    Topics: Behavior Therapy; Buspirone; Cannabinoids; Cognitive Behavioral Therapy; Combined Modality Therapy; Dronabinol; Humans; Marijuana Abuse; Mianserin; Mirtazapine; Motivation; Piperidines; Psychotherapy; Psychotropic Drugs; Pyrazoles; Randomized Controlled Trials as Topic; Rimonabant; Substance Withdrawal Syndrome

2008

Trials

4 trial(s) available for sr141716 and Cannabis Abuse

ArticleYear
CB1 - cannabinoid receptor antagonist effects on cortisol in cannabis-dependent men.
    The American journal of drug and alcohol abuse, 2012, Volume: 38, Issue:1

    Topics: Double-Blind Method; Dronabinol; Drug Administration Schedule; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Marijuana Abuse; Piperidines; Pituitary-Adrenal System; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant

2012
Antagonist-elicited cannabis withdrawal in humans.
    Journal of clinical psychopharmacology, 2011, Volume: 31, Issue:5

    Topics: Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Humans; Male; Marijuana Abuse; Mass Spectrometry; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance Withdrawal Syndrome; Young Adult

2011
Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis users.
    Psychopharmacology, 2007, Volume: 194, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Drug Administration Schedule; Electrocardiography; Heart Rate; Humans; Male; Marijuana Abuse; Marijuana Smoking; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Sex Factors; Tachycardia; Time Factors

2007
Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716.
    Archives of general psychiatry, 2001, Volume: 58, Issue:4

    Topics: Administration, Oral; Adult; Animals; Cannabinoids; Dose-Response Relationship, Drug; Double-Blind Method; Dronabinol; Euphoria; Heart Rate; Humans; Male; Marijuana Abuse; Piperidines; Placebos; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tachycardia

2001

Other Studies

16 other study(ies) available for sr141716 and Cannabis Abuse

ArticleYear
Novel behavioral assays of spontaneous and precipitated THC withdrawal in mice.
    Drug and alcohol dependence, 2018, Oct-01, Volume: 191

    Topics: Animals; Behavior, Animal; Benzodioxoles; Cannabinoid Receptor Agonists; Dronabinol; Indoles; Male; Marijuana Abuse; Mice; Mice, Inbred C57BL; Naphthalenes; Piperidines; Pyrazoles; Rimonabant; Substance Withdrawal Syndrome

2018
Neuronal nicotinic acetylcholine receptors mediate ∆
    Addiction biology, 2020, Volume: 25, Issue:1

    Topics: Animals; Cannabinoid Receptor Antagonists; Disease Models, Animal; Dronabinol; Humans; Marijuana Abuse; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Nicotinic; Rimonabant; Substance Withdrawal Syndrome

2020
Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:9

    Topics: Animals; Conditioning, Operant; Cues; Dronabinol; Drug-Seeking Behavior; Male; Marijuana Abuse; Nicotine; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Recurrence; Reinforcement, Psychology; Rimonabant; Saimiri; Self Administration; Tobacco Use Disorder

2016
FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:8

    Topics: Amidohydrolases; Animals; Arachidonic Acids; Behavior, Animal; Benzoxazines; Brain; Cannabinoid Receptor Modulators; Dose-Response Relationship, Drug; Dronabinol; Drug Tolerance; Endocannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); Male; Marijuana Abuse; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Protein Binding; Psychotropic Drugs; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Sulfur Isotopes; Tritium

2010
Altered architecture and functional consequences of the mesolimbic dopamine system in cannabis dependence.
    Addiction biology, 2010, Volume: 15, Issue:3

    Topics: Animals; Axons; Cannabinoids; Dopamine; Limbic System; Male; Marijuana Abuse; Mesencephalon; Neural Pathways; Neurogenesis; Neuronal Plasticity; Neurons; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Substance Withdrawal Syndrome; Substantia Nigra; Synapses; Tyrosine 3-Monooxygenase; Ventral Tegmental Area

2010
delta(9)-Tetrahydrocannabinol-dependent mice undergoing withdrawal display impaired spatial memory.
    Psychopharmacology, 2011, Volume: 217, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Dronabinol; Male; Marijuana Abuse; Maze Learning; Memory Disorders; Memory, Short-Term; Mice; Mice, Inbred C57BL; Piperidines; Pyrazoles; Rimonabant; Spatial Behavior; Substance Withdrawal Syndrome

2011
JWH-018 and JWH-073: Δ⁹-tetrahydrocannabinol-like discriminative stimulus effects in monkeys.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:1

    Topics: Animals; Behavior, Animal; Conditioning, Operant; Data Interpretation, Statistical; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Female; Hallucinogens; Illicit Drugs; Indoles; Macaca mulatta; Male; Marijuana Abuse; Naphthalenes; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Substance Withdrawal Syndrome

2012
Functional tolerance and blockade of long-term depression at synapses in the nucleus accumbens after chronic cannabinoid exposure.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Jun-15, Volume: 23, Issue:12

    Topics: Animals; Benzoxazines; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Dronabinol; Drug Resistance; Drug Tolerance; Electric Stimulation; In Vitro Techniques; Long-Term Synaptic Depression; Male; Marijuana Abuse; Morpholines; Naphthalenes; Nucleus Accumbens; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Opioid, mu; Rimonabant; Synapses; Time

2003
Tolerance to the memory disruptive effects of cannabinoids involves adaptation by hippocampal neurons.
    Hippocampus, 2003, Volume: 13, Issue:5

    Topics: Action Potentials; Adaptation, Physiological; Animals; Benzoxazines; Cannabinoids; Drug Administration Schedule; Drug Tolerance; Hippocampus; Male; Marijuana Abuse; Memory Disorders; Morpholines; Naphthalenes; Neurons; Piperidines; Pyrazoles; Rats; Rats, Long-Evans; Reaction Time; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Substance Withdrawal Syndrome; Synaptic Transmission

2003
Cannabis antagonists: a new era of social psychopharmacology?
    Journal of psychopharmacology (Oxford, England), 2005, Volume: 19, Issue:1

    Topics: Anti-Obesity Agents; Cannabinoids; Cannabis; Humans; Marijuana Abuse; Obesity; Piperidines; Psychopharmacology; Pyrazoles; Rimonabant

2005
Chronic use of marijuana decreases cannabinoid receptor binding and mRNA expression in the human brain.
    Neuroscience, 2007, Mar-02, Volume: 145, Issue:1

    Topics: Adolescent; Adult; Autoradiography; Brain; Cannabis; Case-Control Studies; Gene Expression Regulation; Humans; In Situ Hybridization; Male; Marijuana Abuse; Piperidines; Postmortem Changes; Pyrazoles; Receptors, Cannabinoid; Rimonabant; RNA, Messenger; Tritium

2007
Blockade of THC-seeking behavior and relapse in monkeys by the cannabinoid CB(1)-receptor antagonist rimonabant.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:12

    Topics: Analgesics, Opioid; Animals; Brain; Brain Chemistry; Cannabinoid Receptor Modulators; Cues; Disease Models, Animal; Dronabinol; Drug Administration Schedule; Male; Marijuana Abuse; Morphine; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Saimiri; Secondary Prevention; Self Administration

2008
Changes in the cannabinoid receptor binding, G protein coupling, and cyclic AMP cascade in the CNS of rats tolerant to and dependent on the synthetic cannabinoid compound CP55,940.
    Journal of neurochemistry, 2000, Volume: 75, Issue:5

    Topics: Animals; Behavior, Animal; Brain; Cannabinoids; Cerebellum; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclohexanols; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Drug Tolerance; GTP-Binding Proteins; Hippocampus; Injections, Intraperitoneal; Male; Marijuana Abuse; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Signal Transduction

2000
Cannabinoid antagonists: a treatment in search of an illness.
    Archives of general psychiatry, 2001, Volume: 58, Issue:4

    Topics: Adjuvants, Immunologic; Arachidonic Acids; Cannabinoids; Dronabinol; Endocannabinoids; Humans; Marijuana Abuse; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant

2001
Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Feb-01, Volume: 22, Issue:3

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cannabinoids; Crosses, Genetic; Dronabinol; Drug Tolerance; Hypothermia; Marijuana Abuse; Mice; Mice, Inbred Strains; Mice, Knockout; Motivation; Motor Activity; Piperidines; Psychotropic Drugs; Pyrazoles; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Rimonabant; Spatial Behavior; Substance Withdrawal Syndrome

2002
Antinociceptive, behavioural and neuroendocrine effects of CP 55,940 in young rats.
    Brain research. Developmental brain research, 2002, Jun-30, Volume: 136, Issue:2

    Topics: Analgesics; Animals; Behavior, Animal; Cannabinoids; Corticosterone; Cyclohexanols; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Female; Grooming; Male; Marijuana Abuse; Morphine; Motor Activity; Naloxone; Narcotic Antagonists; Neostriatum; Neurosecretory Systems; Nociceptors; Pain Measurement; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Sex Characteristics

2002