sr141716 has been researched along with Alcohol Abuse in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Douglas, JT; Fantegrossi, WE; Ford, BM; Franks, LN; Prather, PL; Prisinzano, TE; Vasiljevik, T | 1 |
| Adank, D; Butler, E; Johnson, K; Morgan, A; Patel, S | 1 |
| Cooper, TB; Hungund, BL; Thanos, PK; Vadasz, C; Vinod, KY; Volkow, ND; Yalamanchili, R | 1 |
| Soyka, M | 1 |
| Hyytiä, P; Malinen, H | 1 |
| Bishai, R; George, DT; Geyer, C; Heilig, M; Herion, DW; Hersh, J; Hill, D; Jones, CL; Kunos, G; O'Malley, SS; Phillips, MJ; Ramchandani, VA; Rawlings, RR; Singley, ED; Spero, DE | 1 |
| Carai, MA; Colombo, G; Maccioni, P | 1 |
| Delis, F; Gopez, V; Grandy, DK; Kunos, G; Michaelides, M; Thanos, PK; Volkow, ND; Wang, GJ | 1 |
| Dunaj, A; Piątkowska, K; Pietrzak, B | 1 |
| Gallate, JE; McGregor, IS | 1 |
| Doggrell, SA | 1 |
| Bermúdez-Silva, FJ; Bilbao, A; Ciccocioppo, R; Cippitelli, A; de Fonseca, FR; del Arco, I; Hansson, AC; Heilig, M; Massi, M; Navarro, M; Sommer, W | 1 |
| González-Cuevas, G; López-Moreno, JA; Navarro, M | 1 |
| De Witte, P; Lallemand, F | 1 |
| Cabras, C; Carai, MA; Colombo, G; Gessa, GL; Lai, P; Maccioni, P; Orrù, A; Rubio, M | 1 |
| Fehr, C; Gann, H; Koller, G; Lesch, OM; Leweke, M; Mann, KF; Schmidt, P; Soyka, M | 1 |
| Bilbao, A; Koob, GF; Navarro, M; Roberts, AJ; Rodríguez de Fonseca, F | 1 |
5 review(s) available for sr141716 and Alcohol Abuse
| Article | Year |
|---|---|
Rimonabant and depression.
Topics: Alcoholism; Animals; Depression; Humans; Piperidines; Pyrazoles; Rimonabant | 2008 |
Blockade of the cannabinoid CB1 receptor and alcohol dependence: preclinical evidence and preliminary clinical data.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Brain; Cannabinoid Receptor Modulators; Cannabinoids; Disease Models, Animal; Humans; Models, Animal; Narcotic Antagonists; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2010 |
[The role of the cannabinoid system in the pathogenesis and treatment of alcohol dependence].
Topics: Alcohol Drinking; Alcoholism; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Clinical Trials as Topic; Humans; Piperidines; Pyrazoles; Receptors, Cannabinoid; Rimonabant | 2011 |
Will the new CB1 cannabinoid receptor antagonist SR-147778 have advantages over rimonabant?
Topics: Alcoholism; Animals; Humans; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2005 |
The cannabinoid CB1 receptor antagonist, rimonabant, as a promising pharmacotherapy for alcohol dependence: preclinical evidence.
Topics: Alcohol Drinking; Alcoholism; Animals; Humans; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Opioid; Recurrence; Rimonabant | 2007 |
2 trial(s) available for sr141716 and Alcohol Abuse
| Article | Year |
|---|---|
Rimonabant (SR141716) has no effect on alcohol self-administration or endocrine measures in nontreatment-seeking heavy alcohol drinkers.
Topics: Adrenocorticotropic Hormone; Adult; Alcohol Drinking; Alcoholism; Double-Blind Method; Female; Humans; Hydrocortisone; Male; Motivation; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Reward; Rimonabant; Self Administration | 2010 |
Cannabinoid receptor 1 blocker rimonabant (SR 141716) for treatment of alcohol dependence: results from a placebo-controlled, double-blind trial.
Topics: Adult; Alcoholism; Body Mass Index; Body Weight; Double-Blind Method; Female; Humans; Male; Middle Aged; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Secondary Prevention; Treatment Outcome | 2008 |
10 other study(ies) available for sr141716 and Alcohol Abuse
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.
Topics: Alcoholism; Animals; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; CHO Cells; Conditioning, Classical; Cricetinae; Cricetulus; Drug Design; Drug Inverse Agonism; Ethanol; Humans; Indoles; Ligands; Mice; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Self Administration; Structure-Activity Relationship | 2013 |
2-Arachidonoylglycerol-mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice.
Topics: Alcoholism; Animals; Endocannabinoids; Female; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Substance Withdrawal Syndrome | 2022 |
Genetic and pharmacological manipulations of the CB(1) receptor alter ethanol preference and dependence in ethanol preferring and nonpreferring mice.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Analgesics; Animals; Binding, Competitive; Brain; Cyclohexanols; Disease Models, Animal; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Rimonabant; Species Specificity | 2008 |
Ethanol self-administration is regulated by CB1 receptors in the nucleus accumbens and ventral tegmental area in alcohol-preferring AA rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Benzoxazines; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Male; Microinjections; Morpholines; Naphthalenes; Nucleus Accumbens; Piperidines; Pyrazoles; Rats; Rats, Inbred Strains; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Signal Transduction; Ventral Tegmental Area | 2008 |
Upregulation of cannabinoid type 1 receptors in dopamine D2 receptor knockout mice is reversed by chronic forced ethanol consumption.
Topics: Alcohol Drinking; Alcoholism; Animals; Body Weight; Central Nervous System Depressants; Dopamine; Ethanol; Male; Mice; Mice, Knockout; Motor Activity; Neostriatum; Nucleus Accumbens; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Dopamine D2; Rimonabant; Synaptic Transmission; Time Factors; Up-Regulation | 2011 |
Rats on the grog: novel pharmacotherapies for alcohol craving.
Topics: Alcoholism; Animals; Baclofen; Beer; Behavior, Addictive; Cannabinoid Receptor Antagonists; Corticotropin-Releasing Hormone; Humans; Models, Animal; Naltrexone; Narcotic Antagonists; Neuropeptide Y; Piperidines; Pyrazoles; Rats; Receptors, Corticotropin-Releasing Hormone; Receptors, GABA-B; Research Design; Rimonabant | 2004 |
Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats.
Topics: Alcoholism; Animals; Behavior, Animal; Brain; Central Nervous System Depressants; Conditioning, Operant; Dose-Response Relationship, Drug; Ethanol; Food; In Situ Hybridization; Male; Motor Activity; Piperidines; Pyrazoles; Rats; Rats, Mutant Strains; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Self Administration | 2005 |
The CB1 cannabinoid receptor antagonist rimonabant chronically prevents the nicotine-induced relapse to alcohol.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Anxiety Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Synergism; Male; Maze Learning; Nicotine; Nicotinic Agonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reinforcement, Psychology; Rimonabant; Secondary Prevention; Substance Withdrawal Syndrome; Sucrose | 2007 |
SR147778, a CB1 cannabinoid receptor antagonist, suppresses ethanol preference in chronically alcoholized Wistar rats.
Topics: Alcoholism; Animals; Disease Models, Animal; Food Preferences; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Rimonabant; Sucrose | 2006 |
Cannabinoid receptor antagonist SR141716A decreases operant ethanol self administration in rats exposed to ethanol-vapor chambers.
Topics: Alcoholism; Animals; Cannabinoids; Conditioning, Operant; Ethanol; Male; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Self Administration; Substance-Related Disorders | 1999 |