spironolactone has been researched along with Vibrio cholerae Infection in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study demonstrated that endogenous aldosterone, as determined by its transient competitive block by spironolactone, caused significant sodium and chloride retention during naturally acquired cholera." | 7.65 | Effect of spironolactone on stool electrolyte losses during human cholera. ( Chen, LC; Guerrant, RL; Rohde, JE, 1972) |
| "This study demonstrated that endogenous aldosterone, as determined by its transient competitive block by spironolactone, caused significant sodium and chloride retention during naturally acquired cholera." | 3.65 | Effect of spironolactone on stool electrolyte losses during human cholera. ( Chen, LC; Guerrant, RL; Rohde, JE, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guerrant, RL | 1 |
| Chen, LC | 1 |
| Rohde, JE | 1 |
1 other study available for spironolactone and Vibrio cholerae Infection
| Article | Year |
|---|---|
Effect of spironolactone on stool electrolyte losses during human cholera.
Topics: Adult; Aldosterone; Chlorides; Cholera; Diarrhea; Feces; Humans; Male; Potassium; Sodium; Spironolac | 1972 |