spironolactone has been researched along with Uterine Neoplasms in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment of aldosterone increased the levels of Ang II type-1 receptor mRNA." | 5.36 | Aldosterone stimulates the proliferation of uterine leiomyoma cells. ( Isobe, A; Kimura, T; Li, B; Sakata, M; Takeda, T; Tsuiji, K; Wakabayashi, A; Yaegashi, N, 2010) |
| "Treatment of aldosterone increased the levels of Ang II type-1 receptor mRNA." | 1.36 | Aldosterone stimulates the proliferation of uterine leiomyoma cells. ( Isobe, A; Kimura, T; Li, B; Sakata, M; Takeda, T; Tsuiji, K; Wakabayashi, A; Yaegashi, N, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Isobe, A | 1 |
| Takeda, T | 1 |
| Wakabayashi, A | 1 |
| Tsuiji, K | 1 |
| Li, B | 1 |
| Sakata, M | 1 |
| Yaegashi, N | 1 |
| Kimura, T | 1 |
| Biggar, RJ | 1 |
| ABBES, M | 1 |
| CAMBON, P | 1 |
| PAILLAUD, F | 1 |
| Tragl, KH | 1 |
1 review available for spironolactone and Uterine Neoplasms
| Article | Year |
|---|---|
Molecular pathways: digoxin use and estrogen-sensitive cancers--risks and possible therapeutic implications.
Topics: Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Digoxin; Estrogens; Female; | 2012 |
3 other studies available for spironolactone and Uterine Neoplasms
| Article | Year |
|---|---|
Aldosterone stimulates the proliferation of uterine leiomyoma cells.
Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cell Division; Cell L | 2010 |
[APPLICATION OF ANTI-ALDOSTERONE DIURETICS TO THE TREATMENT OF LOCALIZED EDEMA OF THE EXTREMITIES IN CANCER PATIENTS].
Topics: Aldosterone; Breast Neoplasms; Diuretics; Edema; Extremities; Female; Humans; Mastectomy; Mineraloco | 1965 |
[Iatrogenic and environmentally caused diseases of the endocrine system in the aged].
Topics: Aged; Cortisone; Cushing Syndrome; Digitalis Glycosides; Endocrine System Diseases; Environmental Ex | 1983 |