spironolactone has been researched along with Thyroid Diseases in 6 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Thyroid Diseases: Pathological processes involving the THYROID GLAND.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female." | 2.61 | Hirsutism in Women. ( Bain, J; Matheson, E, 2019) |
| " Dose-related increases in thyroid-stimulating hormone (TSH) levels were observed in treated animals of both sexes during the dosing period and the changes were statistically significant and correlated with an increased thyroid weight in females at 13 weeks." | 1.27 | The pathologic response of the liver and thyroid of the rat to potassium prorenoate (SC-23992). ( Lumb, GD; Rust, JH, 1985) |
| " The following experiments were performed: I) A relationship was observed between the amount of insulin dosage and the levels of serum potassium, blood sugar, and plasma cyclic AMP or plasma cyclic GMP in normal controls and rats." | 1.26 | [The mechanism of the decrease in serum potassium during insulin-induced hypoglycemia (author's transl)]. ( Aikawa, T, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matheson, E | 1 |
| Bain, J | 1 |
| Aikawa, T | 1 |
| Tragl, KH | 1 |
| Feuillan, PP | 1 |
| Kurata, Y | 1 |
| Wako, Y | 1 |
| Tanaka, K | 1 |
| Inoue, Y | 1 |
| Makinodan, F | 1 |
| Lumb, GD | 1 |
| Rust, JH | 1 |
1 review available for spironolactone and Thyroid Diseases
| Article | Year |
|---|---|
Hirsutism in Women.
Topics: Adrenal Hyperplasia, Congenital; Androgen Antagonists; Antineoplastic Agents, Hormonal; Contraceptiv | 2019 |
5 other studies available for spironolactone and Thyroid Diseases
| Article | Year |
|---|---|
[The mechanism of the decrease in serum potassium during insulin-induced hypoglycemia (author's transl)].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Blood Glucose; Cyclic AMP; Dose-Respo | 1982 |
[Iatrogenic and environmentally caused diseases of the endocrine system in the aged].
Topics: Aged; Cortisone; Cushing Syndrome; Digitalis Glycosides; Endocrine System Diseases; Environmental Ex | 1983 |
McCune-Albright syndrome.
Topics: Adolescent; Calcitriol; Diagnosis, Differential; Female; Fibrous Dysplasia, Polyostotic; Humans; Ket | 1994 |
Thyroid hyperactivity induced by methimazole, spironolactone and phenobarbital in marmosets (Callithrix jacchus): histopathology, plasma thyroid hormone levels and hepatic T4 metabolism.
Topics: Animals; Anticonvulsants; Antithyroid Agents; Biopsy; Callithrix; Cytochrome P-450 Enzyme System; Im | 2000 |
The pathologic response of the liver and thyroid of the rat to potassium prorenoate (SC-23992).
Topics: Animals; Chemical and Drug Induced Liver Injury; Dogs; Female; Lethal Dose 50; Liver; Male; Microsom | 1985 |