spironolactone has been researched along with Thiamine Deficiency in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Thiamine Deficiency: A nutritional condition produced by a deficiency of THIAMINE in the diet, characterized by anorexia, irritability, and weight loss. Later, patients experience weakness, peripheral neuropathy, headache, and tachycardia. In addition to being caused by a poor diet, thiamine deficiency in the United States most commonly occurs as a result of alcoholism, since ethanol interferes with thiamine absorption. In countries relying on polished rice as a dietary staple, BERIBERI prevalence is very high. (From Cecil Textbook of Medicine, 19th ed, p1171)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiamine levels were determined using the erythrocyte transketolase activity." | 6.73 | Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. ( Albanesi Filho, FM; de Albuquerque, DC; Rocha, RM; Silva, GV; Tura, BR, 2008) |
| "Thiamine levels were determined using the erythrocyte transketolase activity." | 2.73 | Influence of spironolactone therapy on thiamine blood levels in patients with heart failure. ( Albanesi Filho, FM; de Albuquerque, DC; Rocha, RM; Silva, GV; Tura, BR, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rocha, RM | 1 |
| Silva, GV | 1 |
| de Albuquerque, DC | 1 |
| Tura, BR | 1 |
| Albanesi Filho, FM | 1 |
1 trial available for spironolactone and Thiamine Deficiency
| Article | Year |
|---|---|
Influence of spironolactone therapy on thiamine blood levels in patients with heart failure.
Topics: Aged; Aged, 80 and over; Chi-Square Distribution; Chronic Disease; Cross-Sectional Studies; Diuretic | 2008 |