spironolactone has been researched along with Spondylitis, Ankylosing in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Spondylitis, Ankylosing: A chronic inflammatory condition affecting the axial joints, such as the SACROILIAC JOINT and other intervertebral or costovertebral joints. It occurs predominantly in young males and is characterized by pain and stiffness of joints (ANKYLOSIS) with inflammation at tendon insertions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic inflammation in ankylosing spondylitis (AS) is associated with vascular endothelial dysfunction which leads to accelerated atherosclerosis." | 1.39 | Spironolactone improves endothelial dysfunction in ankylosing spondylitis. ( Garg, N; Kaur, L; Khichi, D; Syngle, A; Verma, I; Vohra, K, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Syngle, A | 1 |
| Vohra, K | 1 |
| Khichi, D | 1 |
| Garg, N | 1 |
| Verma, I | 1 |
| Kaur, L | 1 |
| Suh, YS | 1 |
| Kim, HO | 1 |
| Cheon, YH | 1 |
| Jo, W | 1 |
| Hong, J | 1 |
| Lee, SI | 1 |
1 review available for spironolactone and Spondylitis, Ankylosing
| Article | Year |
|---|---|
Ankylosing spondylitis associated with primary aldosteronism in a middle-aged woman.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Biological Products; Biomarkers; Drug | 2017 |
1 other study available for spironolactone and Spondylitis, Ankylosing
| Article | Year |
|---|---|
Spironolactone improves endothelial dysfunction in ankylosing spondylitis.
Topics: Adolescent; Adult; Atherosclerosis; Blood Sedimentation; Brachial Artery; C-Reactive Protein; Diuret | 2013 |