spironolactone has been researched along with Sicca Syndrome in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acquired Gitelman syndrome is a very rare disorder reported in association with autoimmune disorders, mostly Sjögren syndrome." | 2.72 | Hypokalaemic paralysis and metabolic alkalosis in a patient with Sjögren syndrome: a case report and literature review. ( Gunapala, A; Perera, S; Ranaweerage, R, 2021) |
| "The complications to renal tubular acidosis such as hypokalemic muscle paralysis or chronic muscle weakness, nephrolithiasis, and osteomalacia can be avoided if the diagnosis of renal tubular acidosis is made and corrective alkali therapy is maintained." | 1.27 | Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis. ( Christensen, KS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ranaweerage, R | 1 |
| Perera, S | 1 |
| Gunapala, A | 1 |
| Christensen, KS | 1 |
1 review available for spironolactone and Sicca Syndrome
| Article | Year |
|---|---|
Hypokalaemic paralysis and metabolic alkalosis in a patient with Sjögren syndrome: a case report and literature review.
Topics: Diagnosis, Differential; Dietary Supplements; Gitelman Syndrome; Humans; Hypokalemia; Paralysis; Pot | 2021 |
1 other study available for spironolactone and Sicca Syndrome
| Article | Year |
|---|---|
Hypokalemic paralysis in Sjögren's syndrome secondary to renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Bicarbonates; Female; Humans; Hypokalemia; Middle Aged; Paralysis; Potassiu | 1985 |