spironolactone has been researched along with Schistosoma mansoni Infection in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Portopulmonary hypertension is characterized by a chronic liver disease associated with a mean pulmonary artery pressure >25 mmHg at rest, an increased pulmonary vascular resistance and a capillary pulmonary pressure <15 mmHg with portal hypertension." | 1.34 | [Portopulmonary hypertension due to schistosomiasis in two Malagasy patients]. ( Rajaona, HR; Rajaonarivelo, P; Ramanampamonjy, RM; Razafimahefa, SH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abd El Hady, WE | 1 |
| El-Emam, GA | 1 |
| Saleh, NE | 1 |
| Hamouda, MM | 1 |
| Motawea, A | 1 |
| Ramanampamonjy, RM | 1 |
| Razafimahefa, SH | 1 |
| Rajaonarivelo, P | 1 |
| Rajaona, HR | 1 |
2 other studies available for spironolactone and Schistosoma mansoni Infection
| Article | Year |
|---|---|
The Idiosyncratic Efficacy of Spironolactone-Loaded PLGA Nanoparticles Against Murine Intestinal Schistosomiasis.
Topics: Animals; Liver; Mice; Nanoparticles; Schistosomiasis mansoni; Spectroscopy, Fourier Transform Infrar | 2023 |
[Portopulmonary hypertension due to schistosomiasis in two Malagasy patients].
Topics: Adolescent; Adult; Anthelmintics; Ascites; Combined Modality Therapy; Diet, Sodium-Restricted; Dyspn | 2007 |