spironolactone has been researched along with Sarcoidosis in 4 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Sarcoidosis: An idiopathic systemic inflammatory granulomatous disorder comprised of epithelioid and multinucleated giant cells with little necrosis. It usually invades the lungs with fibrosis and may also involve lymph nodes, skin, liver, spleen, eyes, phalangeal bones, and parotid glands.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Under this point of view and in connection with it the conception to apply cortisone in a combination as low as possible or even to avoid it al all, aldactone has been applied by way of trial in the therapy of the sarcoidosis of the lungs." | 3.65 | [Aldactone in the treatment of sarcoidosis of the lungs (author's transl)]. ( Wandelt-Freerksen, E, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ETIENNE-MARTIN, P | 1 |
| KLEPPING, C | 1 |
| BARTHES, J | 1 |
| GUERRIN, A | 1 |
| Wandelt-Freerksen, E | 1 |
| Prati, RC | 1 |
| Alfrey, AC | 1 |
| Hull, AR | 1 |
1 trial available for spironolactone and Sarcoidosis
| Article | Year |
|---|---|
Spironolactone-induced hypercalciuria.
Topics: Administration, Oral; Autoanalysis; Calcium; Clinical Trials as Topic; Diuretics; Humans; Placebos; | 1972 |
3 other studies available for spironolactone and Sarcoidosis
| Article | Year |
|---|---|
[Pure nephrotic syndrome treated with spirolactone in the course of a Besnier-Boeck-Schaumann disease with pulmonary, hepatic and osseous involvement].
Topics: Aldosterone; Bone and Bones; Diuretics; Liver; Mineralocorticoid Receptor Antagonists; Nephrotic Syn | 1961 |
Taste and smell in disease.
Topics: Aged; Dengue; Female; Humans; Male; Sarcoidosis; Smell; Spironolactone; Taste | 1983 |
[Aldactone in the treatment of sarcoidosis of the lungs (author's transl)].
Topics: Biopsy; Cortisone; Drug Synergism; Humans; Lung Diseases; Sarcoidosis; Spironolactone | 1977 |