spironolactone has been researched along with Rheumatic Heart Disease in 15 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Rheumatic Heart Disease: Cardiac manifestation of systemic rheumatological conditions, such as RHEUMATIC FEVER. Rheumatic heart disease can involve any part the heart, most often the HEART VALVES and the ENDOCARDIUM.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BARNETT, AJ | 1 |
| BAUMGARTEN, A | 1 |
| BRANDSTATER, M | 1 |
| SANDERS, LL | 1 |
| MELBY, JC | 1 |
| LOCKWOOD, CH | 1 |
| NICHOLLS, DM | 1 |
| LEWIS, JA | 1 |
| TROOP, VL | 1 |
| BELLISARIO, G | 1 |
| CORDOVA, C | 1 |
| LOCOCO, G | 1 |
| NATOLI, A | 1 |
| SANTUCCI, A | 1 |
| METCALF, MG | 1 |
| Vinogradov, AV | 5 |
| Sycheva, IM | 5 |
| Zhuravleva, IA | 1 |
| Zamotaev, IP | 1 |
| Kabakov, AI | 1 |
| Perchikova, GE | 1 |
| Tsibekmakher, TD | 1 |
| Speranskaia, NV | 2 |
| Kramer, AA | 2 |
| Ignatova, TA | 2 |
| Bezborod'ko, BN | 1 |
| Shekhunova, MI | 1 |
| Selivonenko, VG | 1 |
| Krater, AA | 1 |
| Kuz'mina, AE | 1 |
| Kiseleva, ZM | 1 |
| Matveev, LN | 1 |
| White, R | 1 |
| McAlister, J | 1 |
| Hamer, J | 1 |
| Antalóczy, Z | 1 |
| Ludvigh, G | 1 |
2 trials available for spironolactone and Rheumatic Heart Disease
| Article | Year |
|---|---|
[Fluid redistribution between the extracellular medium and the cells in the diuretic therapy of cardiac insufficiency].
Topics: Adult; Aged; Body Water; Cardiac Glycosides; Clinical Trials as Topic; Coronary Disease; Diuretics; | 1975 |
[Comparative evaluation of the effectiveness of diuretics].
Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Diuresis; Diur | 1976 |
13 other studies available for spironolactone and Rheumatic Heart Disease
| Article | Year |
|---|---|
OBSERVATIONS ON TRIAMTERENE--A NEW DIURETIC.
Topics: Chlorides; Chlorothiazide; Coronary Disease; Craniocerebral Trauma; Diuretics; Edema; Geriatrics; He | 1963 |
ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE.
Topics: Aldosterone; Chromatography; Diuretics; Edema; Geriatrics; Heart Diseases; Heart Failure; Hypertensi | 1964 |
THE DIURETIC EFFECT OF TRIAMTERENE.
Topics: Blood Chemical Analysis; Coronary Disease; Creatine; Creatinine; Diuretics; Heart Failure; Hypertens | 1964 |
[PRELIMINARY RESULTS OF THE USE OF SPIROLACTONE IN PATIENTS WITH CIRCULATORY INSUFFICIENCY].
Topics: Body Weight; Diuresis; Electrolytes; Heart Failure; Humans; Pericarditis; Pericarditis, Constrictive | 1963 |
SPIRONOLACTONE AND PLASMA CORTISOL.
Topics: Blood Chemical Analysis; Humans; Hydrocortisone; Kidney Diseases; Pharmacology; Rheumatic Heart Dise | 1964 |
[Treatment of refractory chronic circulatory insufficiency].
Topics: Adult; Aged; Benzothiadiazines; Cardiac Glycosides; Cardiomyopathies; Chronic Disease; Coronary Dise | 1976 |
[Alterations in water-salt metabolism under the influence of diuretics in cardiac insufficiency].
Topics: Adult; Aged; Arteriosclerosis; Coronary Disease; Ethacrynic Acid; Female; Heart Failure; Humans; Mal | 1973 |
[Use of aldactone and veroshpiron in complex therapy of patients with circulation disorders].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Calcium; Female; Heart Diseases; Humans; Hypertension; Ma | 1973 |
[Changes in water-salt metabolism in cardiac insufficiency under the influence of diuretic preparations].
Topics: Adult; Aged; Arteriosclerosis; Body Fluids; Chronic Disease; Coronary Disease; Diet Therapy; Ethacry | 1973 |
[Distribution of fluid between the cells and the extracellular media and mineralocorticoid function of the adrenal glands in cardiac insufficiency].
Topics: Adrenal Glands; Adult; Aldosterone; Antipyrine; Body Fluids; Chromatography, Paper; Coronary Disease | 1969 |
[Concentration of metabolizable sodium in patients with circulatory insufficiency].
Topics: Adult; Aged; Arteriosclerosis; Female; Heart Failure; Humans; Male; Middle Aged; Rheumatic Heart Dis | 1971 |
Effect of spironolactone on body potassium in heart failure and hypertension.
Topics: Body Composition; Cell Membrane; Heart Failure; Humans; Hypertension; Potassium; Rheumatic Heart Dis | 1969 |
[Secondary hyperaldosteronism as a secondary disease in intractable cardiac decompensation].
Topics: Adult; Cardiac Surgical Procedures; Digitalis Glycosides; Diuresis; Electrocardiography; Female; Hea | 1965 |