spironolactone has been researched along with Rhabdomyolysis in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia." | 5.35 | An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009) |
| " With the discontinuation of the licorice-containing medicines and administration of spironolactone together with intravenous and oral potassium supplement, her serum potassium level was normalized and her clinical symptoms and hypertension improved within 2 weeks." | 3.74 | Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice. ( Harada, E; Itoh, T; Mizuno, Y; Yasue, H, 2007) |
| "Primary hyperaldosteronism is characterised by hypertension, hypokalemia, suppressed plasma renin activity, and increased aldosterone excretion." | 2.45 | Rhabdomyolysis due to primary hyperaldosteronism. ( Corrales, PP; López, AH; Martínez, JJ; Meneses, AL; Oliveira, CL; Rodríguez, SA; Romero, FB, 2009) |
| "Rhabdomyolysis is a rare presentation of hypokalemia, although muscle weakness is a well known manifestation of marked hypokalemia." | 1.35 | An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis. ( Ahmetoğlu, A; Bahat, E; Imamoğlu, M; Karagüzel, G; Okten, A; Yildiz, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinoshita, H | 1 |
| Okabayashi, M | 1 |
| Kaneko, M | 1 |
| Yasuda, M | 1 |
| Abe, K | 1 |
| Machida, A | 1 |
| Ohkubo, T | 1 |
| Kamata, T | 1 |
| Yakushiji, F | 1 |
| Martínez, JJ | 1 |
| Oliveira, CL | 1 |
| Meneses, AL | 1 |
| Rodríguez, SA | 1 |
| Corrales, PP | 1 |
| López, AH | 1 |
| Romero, FB | 1 |
| Karagüzel, G | 1 |
| Bahat, E | 1 |
| Imamoğlu, M | 1 |
| Ahmetoğlu, A | 1 |
| Yildiz, K | 1 |
| Okten, A | 1 |
| Yasue, H | 1 |
| Itoh, T | 1 |
| Mizuno, Y | 1 |
| Harada, E | 1 |
| Carmona-Bayonas, A | 1 |
| Soler, IO | 1 |
| Gómez, FI | 1 |
| Billalabeitia, EG | 1 |
| Saura, HP | 1 |
| Tafalla, MS | 1 |
| Díaz, MP | 1 |
1 review available for spironolactone and Rhabdomyolysis
| Article | Year |
|---|---|
Rhabdomyolysis due to primary hyperaldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Female; Humans; Hyperaldosteronism; Hyperten | 2009 |
4 other studies available for spironolactone and Rhabdomyolysis
| Article | Year |
|---|---|
Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels.
Topics: Aged; Alkalosis; Drug Combinations; Drugs, Chinese Herbal; Electrocardiography; Female; Glycyrrhiza; | 2009 |
An unusual case of an aldosterone-producing adrenocortical adenoma presenting with rhabdomyolysis.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenalectomy; Adrenocortical Adenoma; Aldoste | 2009 |
Severe hypokalemia, rhabdomyolysis, muscle paralysis, and respiratory impairment in a hypertensive patient taking herbal medicines containing licorice.
Topics: Administration, Oral; Aged, 80 and over; Female; Glycyrrhiza; Humans; Hypertension; Hypokalemia; Inj | 2007 |
Tailored hormonal therapy in secretory adrenocortical cancer.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Aged; Aldosterone; Alkalosis; Ang | 2007 |