spironolactone has been researched along with Retinal Detachment in 2 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
| Excerpt | Relevance | Reference |
|---|---|---|
| "After treatment with spironolactone, both patients showed a visual acuity improvement and structural changes (reduced neurosensory retinal detachment and cystoid degeneration)." | 3.83 | Spironolactone, a therapeutic alternative in the treatment of diffuse retinal pigment epitheliopathy. ( Abreu Reyes, JA; Ángel-Pereira, D; Blasco Alberto, A; Cordovés-Dorta, L; Losada Castillo, MJ; Rocha-Cabrera, P, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ángel-Pereira, D | 1 |
| Rocha-Cabrera, P | 1 |
| Cordovés-Dorta, L | 1 |
| Losada Castillo, MJ | 1 |
| Blasco Alberto, A | 1 |
| Abreu Reyes, JA | 1 |
| Paris, GL | 1 |
| Macoul, KL | 1 |
2 other studies available for spironolactone and Retinal Detachment
| Article | Year |
|---|---|
Spironolactone, a therapeutic alternative in the treatment of diffuse retinal pigment epitheliopathy.
Topics: Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; Retinal Detachment; Spironolacton | 2016 |
Reversible bullous retinal detachment in chronic renal disease.
Topics: Adult; Angiography; Diet; Female; Fluorescence; Humans; Hydrochlorothiazide; Hypertension, Renal; Hy | 1969 |