spironolactone has been researched along with Reflex, Abnormal in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Reflex, Abnormal: An abnormal response to a stimulus applied to the sensory components of the nervous system. This may take the form of increased, decreased, or absent reflexes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is attributed to sodium retention in the distal nephron, but 11βHSD2 is also expressed in the brain." | 1.43 | Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension. ( Al-Dujaili, EA; Bailey, MA; Christensen, TH; Evans, LC; Holmes, MC; Ivy, JR; Kenyon, CJ; McNairn, JA; Menzies, RI; Mullins, JJ; Seckl, JR; Wyrwoll, C, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Evans, LC | 1 |
| Ivy, JR | 1 |
| Wyrwoll, C | 1 |
| McNairn, JA | 1 |
| Menzies, RI | 1 |
| Christensen, TH | 1 |
| Al-Dujaili, EA | 1 |
| Kenyon, CJ | 1 |
| Mullins, JJ | 1 |
| Seckl, JR | 1 |
| Holmes, MC | 1 |
| Bailey, MA | 1 |
1 other study available for spironolactone and Reflex, Abnormal
| Article | Year |
|---|---|
Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Animals; Baroreflex; Corticosterone; Craving; Dexametha | 2016 |