spironolactone has been researched along with Pseudohypoaldosteronism in 3 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Pseudohypoaldosteronism: A heterogeneous group of disorders characterized by renal electrolyte transport dysfunctions. Congenital forms are rare autosomal disorders characterized by neonatal hypertension, HYPERKALEMIA, increased RENIN activity and ALDOSTERONE concentration. The Type I features HYPERKALEMIA with sodium wasting; Type II, HYPERKALEMIA without sodium wasting. Pseudohypoaldosteronism can be the result of a defective renal electrolyte transport protein or acquired after KIDNEY TRANSPLANTATION.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castañeda-Bueno, M | 1 |
| Arroyo, JP | 1 |
| Zhang, J | 1 |
| Puthumana, J | 1 |
| Yarborough, O | 1 |
| Shibata, S | 1 |
| Rojas-Vega, L | 1 |
| Gamba, G | 1 |
| Rinehart, J | 1 |
| Lifton, RP | 1 |
| Kinoshita, H | 1 |
| Okabayashi, M | 1 |
| Kaneko, M | 1 |
| Yasuda, M | 1 |
| Abe, K | 1 |
| Machida, A | 1 |
| Ohkubo, T | 1 |
| Kamata, T | 1 |
| Yakushiji, F | 1 |
| Funder, JW | 1 |
| Pearce, PT | 1 |
| Myles, K | 1 |
| Roy, LP | 1 |
3 other studies available for spironolactone and Pseudohypoaldosteronism
| Article | Year |
|---|---|
Phosphorylation by PKC and PKA regulate the kinase activity and downstream signaling of WNK4.
Topics: Angiotensin II; Animals; Blood Volume; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein | 2017 |
Shakuyaku-kanzo-to induces pseudoaldosteronism characterized by hypokalemia, rhabdomyolysis, metabolic alkalosis with respiratory compensation, and increased urinary cortisol levels.
Topics: Aged; Alkalosis; Drug Combinations; Drugs, Chinese Herbal; Electrocardiography; Female; Glycyrrhiza; | 2009 |
Apparent mineralocorticoid excess, pseudohypoaldosteronism, and urinary electrolyte excretion: toward a redefinition of mineralocorticoid action.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Adrenalectomy; Aldosterone; Androstanols; Animals; Bicarbonat | 1990 |