spironolactone has been researched along with Premenstrual Tension in 18 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Premenstrual Tension: A term used to describe the psychological aspects of PREMENSTRUAL SYNDROME, such as the indescribable tension, depression, hostility, and increased seizure activity in women with seizure disorder.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To reevaluate whether spironolactone, a steroid receptor antagonist, is effective in improving premenstrual syndrome (PMS) in a double-blind, placebo-controlled cross over study." | 9.08 | Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study. ( Bäckström, T; Hammarbäck, S; Lindhe, BA; Wang, M, 1995) |
| "A double blind placebo controlled randomized cross over study was conducted to assess the response to spironolactone by patients suffering from 'Premenstrual Syndrome'." | 9.07 | Premenstrual syndrome and spironolactone. ( Burnet, RB; Easterbrook, EG; McKinnon, RA; Radden, HS, 1991) |
| "The effect of spironolactone in the alleviation of the symptoms of the premenstrual syndrome was compared with placebo in a double-blind, parallel group controlled study." | 9.06 | A double-blind, placebo-controlled evaluation of spironolactone in the premenstrual syndrome. ( Akbar, FA; Pearce, MY; Shroff, NE; Stratford, ME; Vellacott, ID, 1987) |
| "To reevaluate whether spironolactone, a steroid receptor antagonist, is effective in improving premenstrual syndrome (PMS) in a double-blind, placebo-controlled cross over study." | 5.08 | Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study. ( Bäckström, T; Hammarbäck, S; Lindhe, BA; Wang, M, 1995) |
| "A double blind placebo controlled randomized cross over study was conducted to assess the response to spironolactone by patients suffering from 'Premenstrual Syndrome'." | 5.07 | Premenstrual syndrome and spironolactone. ( Burnet, RB; Easterbrook, EG; McKinnon, RA; Radden, HS, 1991) |
| "The effect of spironolactone in the alleviation of the symptoms of the premenstrual syndrome was compared with placebo in a double-blind, parallel group controlled study." | 5.06 | A double-blind, placebo-controlled evaluation of spironolactone in the premenstrual syndrome. ( Akbar, FA; Pearce, MY; Shroff, NE; Stratford, ME; Vellacott, ID, 1987) |
| "The premenstrual syndrome is diagnosed historically, with symptoms recorded meticulously on a menstrual calendar." | 2.36 | Drug therapy for the premenstrual syndrome. ( Shangold, MM, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wyatt, K | 1 |
| DEMARTINIS, C | 1 |
| FONZO, D | 1 |
| DELVAGLIO, B | 1 |
| Rapkin, AJ | 2 |
| Mikacich, JA | 1 |
| Kroll, R | 1 |
| Shangold, MM | 1 |
| Simmons, MK | 1 |
| Wang, M | 1 |
| Hammarbäck, S | 1 |
| Lindhe, BA | 1 |
| Bäckström, T | 1 |
| Johnson, SR | 1 |
| Gianetto-Berruti, A | 1 |
| Feyles, V | 1 |
| O'Brien, PM | 2 |
| Craven, D | 1 |
| Selby, C | 1 |
| Symonds, EM | 1 |
| Hendler, N | 1 |
| Hellberg, D | 1 |
| Claesson, B | 1 |
| Nilsson, S | 1 |
| Burnet, RB | 1 |
| Radden, HS | 1 |
| Easterbrook, EG | 1 |
| McKinnon, RA | 1 |
| McMurchie, M | 1 |
| Hindmarsh, E | 1 |
| Vellacott, ID | 2 |
| Shroff, NE | 1 |
| Pearce, MY | 1 |
| Stratford, ME | 1 |
| Akbar, FA | 1 |
8 reviews available for spironolactone and Premenstrual Tension
| Article | Year |
|---|---|
Premenstrual syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cognitive Behavioral Therapy; Estrogen Replacement Therapy; | 2002 |
[SECONDARY HYPERALDOSTERONISM. PHYSIOPATHOLOGIC, CLINICAL AND THERAPEUTIC CONSIDERATIONS].
Topics: Adrenal Cortex Hormones; Angiotensins; Blood Transfusion; Capillary Permeability; Diet; Diet Therapy | 1963 |
Premenstrual syndrome in adolescents: diagnosis and treatment.
Topics: Adolescent; Androstenes; Calcium; Female; Humans; Mood Disorders; Patient Education as Topic; Premen | 2006 |
Treatment of premenstrual disorders.
Topics: Alprazolam; Androstenes; Cognitive Behavioral Therapy; Contraceptives, Oral; Exercise; Female; Gonad | 2006 |
Drug therapy for the premenstrual syndrome.
Topics: Bromocriptine; Female; Humans; Premenstrual Syndrome; Progesterone; Pyridoxine; Spironolactone; Synd | 1983 |
Premenstrual syndrome therapy.
Topics: Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Bromocriptine; Contraceptives, Oral, C | 1998 |
Premenstrual syndrome.
Topics: Anti-Anxiety Agents; Clinical Trials as Topic; Contraceptives, Oral; Danazol; Diagnosis, Differentia | 2002 |
Effect of spironolactone on premenstrual syndrome symptoms.
Topics: Adult; Aldosterone; Body Water; Body Weight; Diuretics; Female; Humans; Premenstrual Syndrome; Renin | 1987 |
5 trials available for spironolactone and Premenstrual Tension
| Article | Year |
|---|---|
Treatment of premenstrual syndrome by spironolactone: a double-blind, placebo-controlled study.
Topics: Adult; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Humans; Menstrual Cycle | 1995 |
Treatment of premenstrual syndrome by spironolactone.
Topics: Aldosterone; Body Weight; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Menstruatio | 1979 |
Premenstrual tension: a placebo-controlled efficacy study with spironolactone and medroxyprogesterone acetate.
Topics: Adult; Drug Evaluation; Female; Humans; Medroxyprogesterone; Middle Aged; Placebos; Premenstrual Syn | 1991 |
Premenstrual syndrome and spironolactone.
Topics: Androgens; Depression; Double-Blind Method; Female; Humans; Premenstrual Syndrome; Spironolactone | 1991 |
A double-blind, placebo-controlled evaluation of spironolactone in the premenstrual syndrome.
Topics: Adult; Aldosterone; Double-Blind Method; Drug Evaluation; Female; Humans; Middle Aged; Patient Dropo | 1987 |
5 other studies available for spironolactone and Premenstrual Tension
| Article | Year |
|---|---|
[Studies on the actions of 17-spirolactones. I. Action on the premenstrual syndrome].
Topics: Female; Humans; Lactones; Premenstrual Syndrome; Spironolactone | 1960 |
[EDEMAS AND SPIRONOLACTONES].
Topics: Edema; Female; Glomerulonephritis; Humans; Nephritis; Pregnancy; Pregnancy Complications; Premenstru | 1964 |
Possible new relief for premenstrual syndrome.
Topics: Female; Humans; Premenstrual Syndrome; Spironolactone; Syndrome | 1983 |
Spironolactone for the treatment of PMS.
Topics: Buspirone; Female; Humans; Premenstrual Syndrome; Spironolactone | 1992 |
Premenstrual syndrome. A general practice view.
Topics: Contraceptives, Oral; Female; Humans; Life Style; Mefenamic Acid; Premenstrual Syndrome; Pyridoxine; | 1989 |