spironolactone has been researched along with Pheochromocytoma in 5 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The recent introduction of a novel, long-acting testosterone formulation (testosterone undecanoate) which only requires one intramuscular injection every 3 months, together with the already available hydroalcoholic testosterone gels, appear to be promising alternatives to the previous standard substitution therapy for male hypogonadism." | 4.83 | [The latest developments in endocrinology 2004/2005]. ( Fottner, C; Weber, MM, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fottner, C | 1 |
| Weber, MM | 1 |
| Maebashi, M | 1 |
| Yoshinaga, K | 1 |
| Hofmockel, G | 1 |
| Heimbach, D | 1 |
| Bussen, D | 1 |
| Reincke, M | 1 |
| Frohmüller, HG | 1 |
| Kaplan, NN | 1 |
| Brest, AN | 1 |
| Ruggiero, N | 1 |
3 reviews available for spironolactone and Pheochromocytoma
| Article | Year |
|---|---|
[The latest developments in endocrinology 2004/2005].
Topics: Adrenal Gland Neoplasms; Adult; Bone Density Conservation Agents; Chronic Kidney Disease-Mineral and | 2006 |
Adrenal causes of hypertension.
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Carci | 1974 |
Therapeutic alternatives in hypertension.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Carotid Sinus; Drug Resistance; Electric Stimulation; Human | 1973 |
2 other studies available for spironolactone and Pheochromocytoma
| Article | Year |
|---|---|
Changes in plasma renin activity after administration of spironolactone.
Topics: Adolescent; Adult; Aortic Coarctation; Blood Pressure; Cushing Syndrome; Female; Glomerulonephritis; | 1967 |
[Surgical interventions of the adrenal gland. Diagnosis and results of treatment].
Topics: Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Adenoma; | 1994 |