Page last updated: 2024-11-07

spironolactone and Peritonitis

spironolactone has been researched along with Peritonitis in 15 studies

Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.

Peritonitis: INFLAMMATION of the PERITONEUM lining the ABDOMINAL CAVITY as the result of infectious, autoimmune, or chemical processes. Primary peritonitis is due to infection of the PERITONEAL CAVITY via hematogenous or lymphatic spread and without intra-abdominal source. Secondary peritonitis arises from the ABDOMINAL CAVITY itself through RUPTURE or ABSCESS of intra-abdominal organs.

Research Excerpts

ExcerptRelevanceReference
" Patients without hyperkalemia were administrated 100 mg of spironolactone/day."9.22High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis. ( Demir, M; Dogan, O; Ozer, B; Parlakgumus, A; Serin, E; Yakar, T, 2016)
" Patients without hyperkalemia were administrated 100 mg of spironolactone/day."5.22High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis. ( Demir, M; Dogan, O; Ozer, B; Parlakgumus, A; Serin, E; Yakar, T, 2016)
"Portal hypertension is one of the main consequences of cirrhosis."2.43Current management of the complications of portal hypertension: variceal bleeding and ascites. ( Calès, P; Dib, N; Oberti, F, 2006)
"Peritoneal fibrosis is a complication of patients with long-term continuous ambulatory peritoneal dialysis (CAPD)."1.40The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis. ( Ding, JL; Hao, JB; Hao, LR; Ren, LS; Zhang, L, 2014)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's2 (13.33)18.2507
2000's3 (20.00)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saffouri, GB1
Wittich, CM1
Zhang, L1
Hao, JB1
Ren, LS1
Ding, JL1
Hao, LR1
Moret, M1
Darbellay, P1
Lebowitz, D1
Alves, C1
Sabeh, N1
Carballo, S1
Yakar, T1
Demir, M1
Dogan, O1
Parlakgumus, A1
Ozer, B1
Serin, E1
Hou, W1
Sanyal, AJ1
Dib, N1
Oberti, F1
Calès, P1
Nishimura, H1
Ito, Y1
Mizuno, M1
Tanaka, A1
Morita, Y1
Maruyama, S1
Yuzawa, Y1
Matsuo, S1
de Luis, DA1
Aller, R1
Boixeda, D1
Ruiz Del Arbol, L1
De Argila, CM1
Runyon, BA1
Antillon, MR1
McHutchison, JG1
Panos, M1
Williams, R1
Bruckstein, AH1
Kandel, G1
Diamant, NE1
Selye, H3

Reviews

4 reviews available for spironolactone and Peritonitis

ArticleYear
Ascites: diagnosis and management.
    The Medical clinics of North America, 2009, Volume: 93, Issue:4

    Topics: Ascites; Ascitic Fluid; Cardiac Output; Diet, Sodium-Restricted; Disease Progression; Diuretics; Dru

2009
Current management of the complications of portal hypertension: variceal bleeding and ascites.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006, May-09, Volume: 174, Issue:10

    Topics: Algorithms; Anti-Bacterial Agents; Ascites; Collateral Circulation; Diuretics; Endoscopy, Gastrointe

2006
Management of the patient with ascites.
    Postgraduate medicine, 1987, Volume: 82, Issue:5

    Topics: Ascites; Bacterial Infections; Bed Rest; Diagnosis, Differential; Diuretics; Furosemide; Humans; Liv

1987
A clinical view of recent advances in ascites.
    Journal of clinical gastroenterology, 1986, Volume: 8, Issue:1

    Topics: Animals; Ascites; Ascitic Fluid; Bacterial Infections; Blood Volume; Body Water; Extracellular Space

1986

Trials

1 trial available for spironolactone and Peritonitis

ArticleYear
High Dose Oral Furosemide with Salt Ingestion in the Treatment of Refractory Ascites of Liver Cirrhosis.
    Clinical and investigative medicine. Medecine clinique et experimentale, 2016, Dec-01, Volume: 39, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Albumins; Ascites; Bilirubin; Creatinine; End

2016

Other Studies

10 other studies available for spironolactone and Peritonitis

ArticleYear
83-year-old man with abdominal swelling and lower extremity edema.
    Mayo Clinic proceedings, 2013, Volume: 88, Issue:10

    Topics: Abdominal Cavity; Aged, 80 and over; Anti-Infective Agents; Ascites; Cefotaxime; Diagnosis, Differen

2013
The aldosterone receptor antagonist spironolactone prevents peritoneal inflammation and fibrosis.
    Laboratory investigation; a journal of technical methods and pathology, 2014, Volume: 94, Issue:8

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Cilazapril

2014
[Internal medicine in the hospital setting].
    Revue medicale suisse, 2015, Jan-21, Volume: 11, Issue:458

    Topics: Adrenergic beta-Antagonists; Aminobutyrates; Angiotensin Receptor Antagonists; Asymptomatic Diseases

2015
Mineralocorticoid receptor blockade ameliorates peritoneal fibrosis in new rat peritonitis model.
    American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:5

    Topics: Animals; Blood Pressure; Blotting, Western; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Fi

2008
Spontaneous bacterial peritonitis caused by Citrobacter diversus: case report.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 24, Issue:1

    Topics: Aged; Alcohol Drinking; Ascites; Cefotaxime; Cephalosporins; Citrobacter; Diagnosis, Differential; D

1997
Diuresis increases ascitic fluid opsonic activity in patients who survive spontaneous bacterial peritonitis.
    Journal of hepatology, 1992, Volume: 14, Issue:2-3

    Topics: Amiloride; Ascites; Bacterial Infections; Complement C3; Complement C4; Diuresis; Humans; Liver Cirr

1992
Ascites in cirrhosis: pathophysiology and management.
    British journal of hospital medicine, 1988, Volume: 40, Issue:4

    Topics: Ascites; Diagnosis, Differential; Humans; Inhalation; Liver Cirrhosis; Peritonitis; Spironolactone;

1988
Prevention of indomethacin-induced intestinal ulcers by various catatoxic steroids.
    Experimental medicine and surgery, 1970, Volume: 28, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Antitoxins; Chemical Phenomena; Chemistry; Corticosterone; Ethyles

1970
Effect of catatoxic steroids upon established morbid changes.
    Experientia, 1971, Dec-15, Volume: 27, Issue:12

    Topics: Animals; Digitoxin; Female; Indomethacin; Intestine, Small; Nitriles; Peritonitis; Poisoning; Pregne

1971
Prevention of indomethacin-induced intestinal ulcers by spironolactone and norbolethone.
    Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:12

    Topics: Anabolic Agents; Animals; Digestive System; Female; Indomethacin; Peptic Ulcer; Peritonitis; Rats; S

1969