spironolactone has been researched along with Peripheral Arterial Disease in 1 studies
Spironolactone: A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)
spironolactone : A steroid lactone that is 17alpha-pregn-4-ene-21,17-carbolactone substituted by an oxo group at position 3 and an alpha-acetylsulfanyl group at position 7.
Peripheral Arterial Disease: Lack of perfusion in the EXTREMITIES resulting from atherosclerosis. It is characterized by INTERMITTENT CLAUDICATION, and an ANKLE BRACHIAL INDEX of 0.9 or less.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sandesara, PB | 1 |
| Hammadah, M | 1 |
| Samman-Tahhan, A | 1 |
| Kelli, HM | 1 |
| O'Neal, WT | 1 |
1 trial available for spironolactone and Peripheral Arterial Disease
| Article | Year |
|---|---|
Peripheral artery disease and risk of adverse outcomes in heart failure with preserved ejection fraction.
Topics: Aged; Cause of Death; Female; Heart Failure; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Miner | 2017 |